Publications by authors named "Stefaan Wera"

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Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
Katrien Princen, Tom Van Dooren, Marit van Gorsel, Nikolaos Louros, Xiaojuan Yang, Stefaan Wera

Science· May 2024

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Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.
Michael Dumbacher, Tom Van Dooren, Katrien Princen, Koen De Witte, Mélissa Farinelli, Stefaan Wera

Mol Neurodegener· September 2018

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Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast.
Dries Castermans, Ils Somers, Johan Kriel, Wendy Louwet, Stefaan Wera

Cell Res· June 2012

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Substituted 2-aminothiazoles are exceptional inhibitors of neuronal degeneration in tau-driven models of Alzheimer's disease.
Irene Lagoja, Christophe Pannecouque, Gerard Griffioen, Stefaan Wera, Veronica Maria Rojasdelaparra

Eur J Pharm Sci· August 2011

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A yeast-based model of alpha-synucleinopathy identifies compounds with therapeutic potential.
Gerard Griffioen, Hein Duhamel, Nele Van Damme, Klaartje Pellens, Piotr Zabrocki, Stefaan Wera

Biochim Biophys Acta· March 2006

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Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice.
Tom Van Dooren, David Muyllaert, Peter Borghgraef, Annelies Cresens, Herman Devijver, Ingrid Van der Auwera, Stefaan Wera

Am J Pathol· January 2006

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Virosome-based active immunization targets soluble amyloid species rather than plaques in a transgenic mouse model of Alzheimer's disease.
Rinaldo Zurbriggen, Mario Amacker, Andreas R Kammer, Nicole Westerfeld, Peter Borghgraef, Ingrid Van der Auwera, Stefaan Wera

J Mol Neurosci· December 2005

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Preparation of cyclo-phen-type ligands: chelators of metal ions as potential therapeutic agents in the treatment of neurodegenerative diseases.
Christophe Boldron, Ingrid Van der Auwera, Céline Deraeve, Heinz Gornitzka, Stefaan Wera

Chembiochem· November 2005

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A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease.
Ingrid Van der Auwera, Stefaan Wera, Fred Van Leuven, Samuel T Henderson

Nutr Metab (Lond)· October 2005

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Identification and isolation of a hyperphosphorylated, conformationally changed intermediate of human protein tau expressed in yeast.
Tom Vandebroek, Thomas Vanhelmont, Dick Terwel, Peter Borghgraef, Katleen Lemaire, Stefaan Wera

Biochemistry· August 2005

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Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast.
Piotr Zabrocki, Klaartje Pellens, Thomas Vanhelmont, Tom Vandebroek, Gerard Griffioen, Stefaan Wera

FEBS J· March 2005

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Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice.
René Etcheberrigaray, Mathew Tan, Ilse Dewachter, Cuno Kuipéri, Ingrid Van der Auwera, Stefaan Wera

Proc Natl Acad Sci U S A· July 2004

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Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast.
Renata Tisi, Fiorella Belotti, Stefaan Wera, Joris Winderickx, Johan M Thevelein

Curr Genet· February 2004

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The Saccharomyces cerevisiae type 2A protein phosphatase Pph22p is biochemically different from mammalian PP2A.
Piotr Zabrocki, Wojciech Swiatek, Ewa Sugajska, Johan M Thevelein, Stefaan Wera

Eur J Biochem· July 2002

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Protein phosphatase 2A on track for nutrient-induced signalling in yeast.
Piotr Zabrocki, Christine Van Hoof, Jozef Goris, Johan M Thevelein, Joris Winderickx, Stefaan Wera

Mol Microbiol· February 2002

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