Publications by authors named "Christopher Beadle"

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The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents.
Tim Keuler, Carina Lemke, Paul W Elsinghorst, Isabel Iriepa, Mourad Chioua, Christopher D Beadle

ACS Pharmacol Transl Sci· November 2022

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Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
Óscar M Bautista-Aguilera, Lhassane Ismaili, Mourad Chioua, Rudolf Andrys, Monika Schmidt, Christopher D Beadle

Int J Mol Sci· May 2020

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Chromenones as Multineurotargeting Inhibitors of Human Enzymes.
Carina Lemke, Joscha Christmann, Jiafei Yin, José M Alonso, Estefanía Serrano, Christopher D Beadle

ACS Omega· December 2019

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Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1,3)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor.
Junliang Hao, James P Beck, John M Schaus, Joseph H Krushinski, Qi Chen, Christopher D Beadle

J Med Chem· October 2019

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Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist.
James A Monn, Lourdes Prieto, Lorena Taboada, Junliang Hao, Matthew R Reinhard, Christopher D Beadle

J Med Chem· September 2015

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Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures.
James A Monn, Lourdes Prieto, Lorena Taboada, Concepcion Pedregal, Junliang Hao, Christopher D Beadle

J Med Chem· February 2015

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Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens.
Sanja Ivkovic, Christopher Beadle, Sonal Noticewala, Susan C Massey, Kristin R Swanson

Mol Biol Cell· February 2012

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The ATPase cycle of the mitotic motor CENP-E.
Steven S Rosenfeld, Marilyn van Duffelen, William M Behnke-Parks, Christopher Beadle, John Corrreia

J Biol Chem· November 2009

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The role of myosin II in glioma invasion of the brain.
Christopher Beadle, Marcela C Assanah, Pascale Monzo, Richard Vallee, Steven S Rosenfeld

Mol Biol Cell· August 2008

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Investigation of a flexible enantiospecific approach to aziridines.
Clare E Jamookeeah, Christopher D Beadle, Richard F W Jackson, Joseph P A Harrity

J Org Chem· February 2008

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Leaf angle responds to nitrogen supply in eucalypt seedlings. Is it a photoprotective mechanism?
Dugald C Close, Christopher L Beadle

Tree Physiol· June 2006

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1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors.
Christopher D Beadle, John Boot, Nicholas P Camp, Nancy Dezutter, Jeremy Findlay

Bioorg Med Chem Lett· October 2005

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Photosynthetic capacity and foliar nitrogen distribution in Eucalyptus nitens is altered by high-intensity thinning.
Jane L Medhurst, Christopher L Beadle

Tree Physiol· August 2005

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Chilling-dependent photoinhibition, nutrition and growth analysis of Eucalyptus nitens seedlings during establishment.
Dugald C Close, Christopher L Beadle

Tree Physiol· March 2003

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Measured and predicted changes in tree and stand water use following high-intensity thinning of an 8-year-old Eucalyptus nitens plantation.
Jane L Medhurst, Michael Battaglia, Christopher L Beadle

Tree Physiol· August 2002

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Whole-tree transpiration and water-use partitioning between Eucalyptus nitens and Acacia dealbata weeds in a short-rotation plantation in northeastern Tasmania.
Mark A. Hunt, Christopher L. Beadle

Tree Physiol· January 1998

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