Publications by authors named "Christopher C Williams"

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A tethering mechanism underlies Pin1-catalyzed proline isomerization at a noncanonical site.
Christopher C Williams, Jonathan Chuck, Paola Munoz-Tello, Douglas J Kojetin

Proc Natl Acad Sci U S A· May 2025

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A tethering mechanism underlies Pin1-catalyzed proline isomerization at a noncanonical site.
Christopher C Williams, Jonathan Chuck, Paola Munoz-Tello, Douglas J Kojetin

bioRxiv· March 2025

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Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers.
Christopher L Carroll, Michael G Johnson, Yanbing Ding, Zhijun Kang, R S K Vijayan, Christopher C Williams

J Med Chem· December 2024

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A Case of Infective Endocarditis in a Middle-Aged Patient With Trisomy 21 and an Incidentally Discovered Patent Foramen Ovale (PFO).
Sinead N Bhagwandeen, Girma M Ayele, Amoafo D Boampong, Victoria J Bhagwandeen, Niyati Grewal, Christopher C Williams

Cureus· May 2024

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Glyceollins Trigger Anti-Proliferative Effects in Hormone-Dependent Aromatase-Inhibitor-Resistant Breast Cancer Cells through the Induction of Apoptosis.
Rashidra R Walker, Jankiben R Patel, Akash Gupta, A Michael Davidson, Christopher C Williams

Int J Mol Sci· March 2022

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Discovery of 6-[(3,4)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor.
Barbara Czako, Yuting Sun, Timothy McAfoos, Jason B Cross, Paul G Leonard, Christopher C Williams

J Med Chem· October 2021

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Synthesis of Bench-Stable Quaternized Ketene ,-Acetals and Preliminary Evaluation as Reagents in Organic Synthesis.
Danielle L McConnell, Alisha M Blades, Danielle Gomes Rodrigues, Phoebe V Keyes, Justin C Sonberg, Christopher C Williams

J Org Chem· September 2021

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Systematically Studying the Effect of Small Molecules Interacting with RNA in Cellular and Preclinical Models.
Jessica A Bush, Christopher C Williams, Samantha M Meyer, Yuquan Tong, Hafeez S Haniff

ACS Chem Biol· July 2021

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Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib.
Yuting Sun, Brooke A Meyers, Barbara Czako, Paul Leonard, Faika Mseeh, Christopher C Williams

Cancer Res· November 2020

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Small molecule recognition of disease-relevant RNA structures.
Samantha M Meyer, Christopher C Williams, Yoshihiro Akahori, Toru Tanaka, Haruo Aikawa

Chem Soc Rev· October 2020

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Consideration of Aggressive and Strategic Approaches to Address Declining Enrollment in US Pharmacy Schools.
Nina Pavuluri, Rajender R Aparasu, Kathleen M K Boje, Jennifer Danielson, Shareen Y El-Ibiary, Christopher C Williams

Am J Pharm Educ· August 2019

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Factors Affecting Combination Trial Success (FACTS): Investigator Survey Results on Early-Phase Combination Trials.
Channing J Paller, Erich P Huang, Thomas Luechtefeld, Holly A Massett, Christopher C Williams

Front Med (Lausanne)· June 2019

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Synthesis, Characterization, and Computational Modeling of N-(1-Ethoxyvinyl)pyridinium Triflates, an Unusual Class of Pyridinium Salts.
Jonathan D Shapiro, Justin C Sonberg, Benjamin C Schafer, Christopher C Williams, Hannah R Ferris

Molecules· February 2018

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Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1.
Patrick P Carriere, Shawn D Llopis, Anna C Naiki, Gina Nguyen, Tina Phan, Christopher C Williams

Int J Environ Res Public Health· December 2015

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LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling".
Calvin H Jan, Christopher C Williams, Jonathan S Weissman

Science· June 2015

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Pilot study of methods and equipment for in-home noise level measurements.
Richard L Neitzel, Maire S A Heikkinen, Christopher C Williams, Susan Marie Viet, Michael Dellarco

Appl Acoust· January 2015

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Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling.
Christopher C Williams, Calvin H Jan, Jonathan S Weissman

Science· November 2014

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Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling.
Calvin H Jan, Christopher C Williams, Jonathan S Weissman

Science· November 2014

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Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness.
Syreeta L Tilghman, Ian Townley, Qiu Zhong, Patrick P Carriere, Jin Zou, Christopher C Williams

Mol Cell Proteomics· September 2013

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Metformin induces a senescence-associated gene signature in breast cancer cells.
Christopher C Williams, Brittany A Singleton, Shawn D Llopis, Elena V Skripnikova

J Health Care Poor Underserved· February 2013

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A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress.
Onn Brandman, Jacob Stewart-Ornstein, Daisy Wong, Adam Larson, Christopher C Williams

Cell· November 2012

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The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis.
Philipp Kimmig, Marcy Diaz, Jiashun Zheng, Christopher C Williams, Alexander Lang

Elife· October 2012

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Phosphorylation of Estrogen Receptor α at serine 118 directs recruitment of promoter complexes and gene-specific transcription.
Tamika T Duplessis, Christopher C Williams, Steven M Hill, Brian G Rowan

Endocrinology· June 2011

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A functional NR4A nuclear receptor DNA-binding domain is required for organ development in Caenorhabditis elegans.
Melissa Heard, Claude V Maina, Benjamin E Morehead, Marius C Hoener, Tri Q Nguyen, Christopher C Williams

Genesis· August 2010

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Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.
Christopher C Williams, Aninda Basu, Abeer El-Gharbawy, Latonya M Carrier, Carolyn L Smith

BMC Biochem· December 2009

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