Publications by authors named "Christopher Crean"

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Correction: Comparison of Pharmacokinetics of Long-Acting Local Analgesics: CPL-01, a Novel Extended-Release Ropivacaine, Demonstrates Consistent and Predictable Exposure Compared with Liposomal Bupivacaine.
Stevie Pope, Christopher Crean, Sarah Thrasher, Hanghang Xu, P J Chen

Clin Drug Investig· April 2025

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Comparison of Pharmacokinetics of Long-Acting Local Analgesics: CPL-01, a Novel Extended-Release Ropivacaine, Demonstrates Consistent and Predictable Exposure Compared with Liposomal Bupivacaine.
Stevie Pope, Christopher Crean, Sarah Thrasher, Hanghang Xu, P J Chen

Clin Drug Investig· February 2025

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Ocular and Systemic Pharmacokinetics of Lotilaner Ophthalmic Solution, 0.25%, Following a Single Dose or Repeated Doses in Dutch-Belted Rabbits.
Christopher S Crean, Elizabeth Yeu, Sathi Maiti, Sesha Neervannan

J Ocul Pharmacol Ther· November 2024

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A Phase I, Open-label, Randomized, 2-Way Crossover Study to Evaluate the Relative Bioavailability of Intranasal and Oral Varenicline.
Jeffrey Nau, David J Wyatt, Hans Rollema, Christopher S Crean

Clin Ther· September 2021

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Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery.
Kyle Battiston, Ian Parrag, Matthew Statham, Dimitra Louka, Hans Fischer, Christopher Crean

Nat Commun· May 2021

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Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities.
Karen D Davis, Nima Aghaeepour, Andrew H Ahn, Martin S Angst, David Borsook, Christopher Crean

Nat Rev Neurol· July 2020

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Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles.
Hiroki Tsujinaka, Jie Fu, Jikui Shen, Yun Yu, Zibran Hafiz, Christopher S Crean

Nat Commun· February 2020

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Single-dose pharmacokinetics of bupropion hydrobromide and metabolites in healthy adolescent and adult subjects.
D Alexander Oh, Christopher S Crean

Clin Pharmacol Drug Dev· September 2015

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Effect of hemodialysis on pharmacokinetics of ezogabine/retigabine and its N-acetyl metabolite in patients with end stage renal disease.
Debra J Tompson, Mauro Buraglio, Jonathan Bullman, Christopher S Crean, Kirsty Rayner

Curr Clin Pharmacol· July 2015

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Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug-drug interaction study.
Debra J Tompson, Christopher S Crean, Mauro Buraglio, Thangam Arumugham

Clin Pharmacol· October 2014

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The interaction potential of retigabine (ezogabine) with other antiepileptic drugs.
Debra J Tompson, Christopher S Crean

Curr Clin Pharmacol· May 2014

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Clinical pharmacokinetics of retigabine/ezogabine.
Debra J Tompson, Christopher S Crean

Curr Clin Pharmacol· November 2013

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The effect of ezogabine on the pharmacokinetics of an oral contraceptive agent.
Christopher S Crean, Debra J Tompson, Mauro Buraglio

Int J Clin Pharmacol Ther· November 2013

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Efficacy and tolerability exposure-response relationship of retigabine (ezogabine) immediate-release tablets in patients with partial-onset seizures.
Debra J Tompson, Christopher S Crean, Russell Reeve, N Seth Berry

Clin Ther· August 2013

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The effects of ethanol on the pharmacokinetics, pharmacodynamics, safety, and tolerability of ezogabine (retigabine).
Christopher S Crean, Debra J Tompson

Clin Ther· January 2013

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The spectrum of anticonvulsant efficacy of retigabine (ezogabine) in animal models: implications for clinical use.
Charles H Large, David M Sokal, Astrid Nehlig, Martin J Gunthorpe, Raman Sankar, Christopher S Crean

Epilepsia· March 2012

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Pharmacokinetics of azithromycin and moxifloxacin in human conjunctiva and aqueous humor during and after the approved dosing regimens.
William C Stewart, Christopher S Crean, Richard C Zink, Kurt Brubaker, Reza M Haque

Am J Ophthalmol· November 2010

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Systemic peripheral artery relaxation by KCNQ channel openers and hydrogen sulfide.
Johanna Schleifenbaum, Carolin Köhn, Nadezda Voblova, Galyna Dubrovska, Olga Zavarirskaya, Christopher S Crean

J Hypertens· September 2010

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Ocular surface distribution and pharmacokinetics of a novel ophthalmic 1% azithromycin formulation.
Esen Karamursel Akpek, Jason Vittitow, Rozemarijn S Verhoeven, Kurt Brubaker, Thierry Amar, Christopher Crean

J Ocul Pharmacol Ther· October 2009

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In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models.
Rosemarie Roeloffs, Alan D Wickenden, Christopher Crean, Stephen Werness, Grant McNaughton-Smith

J Pharmacol Exp Ther· September 2008

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Prospective comparative trial of endovaginal sonographic bimanual examination versus traditional digital bimanual examination in nonpregnant women with lower abdominal pain with regard to body mass index classification.
Vivek S Tayal, Christopher A Crean, H James Norton, Christian J Schulz, Katrina N Bacalis

J Ultrasound Med· August 2008

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Rapid and reversible modulation of platelet function in man by a novel P2Y(12) ADP-receptor antagonist, INS50589.
Fred L Johnson, José L Boyer, Philip T Leese, Christopher Crean, Ramesh Krishnamoorthy

Platelets· August 2007

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