Publications by authors named "Christopher D Fjell"

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Increased Plasma PCSK9 Levels Are Associated with Reduced Endotoxin Clearance and the Development of Acute Organ Failures during Sepsis.
John H Boyd, Christopher D Fjell, James A Russell, Demetrios Sirounis, Mihai S Cirstea

J Innate Immun· December 2016

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TNFAIP2 Inhibits Early TNFα-Induced NF-x03BA;B Signaling and Decreases Survival in Septic Shock Patients.
Simone A Thair, Elena Topchiy, John H Boyd, Mihai Cirstea, Catherine Wang, Christopher D Fjell

J Innate Immun· October 2016

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In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents.
Ann M Czyzewski, Håvard Jenssen, Christopher D Fjell, Matt Waldbrook, Nathaniel P Chongsiriwatana

PLoS One· July 2016

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VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock.
Taka-aki Nakada, John H Boyd, James A Russell, Rosalía Aguirre-Hernández, Mark D Wilkinson, Christopher D Fjell

J Innate Immun· June 2016

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An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation.
Olga M Pena, David G Hancock, Ngan H Lyle, Adam Linder, James A Russell, Christopher D Fjell

EBioMedicine· November 2014

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Cytokines and signaling molecules predict clinical outcomes in sepsis.
Christopher D Fjell, Simone Thair, Joseph L Hsu, Keith R Walley, James A Russell

PLoS One· August 2014

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Knockout of extracytoplasmic function sigma factor ECF-10 affects stress resistance and biofilm formation in Pseudomonas putida KT2440.
Beatrix Tettmann, Andreas Dötsch, Olivier Armant, Christopher D Fjell, Joerg Overhage

Appl Environ Microbiol· August 2014

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Prolonged QTc affects short-term and long-term outcomes in patients with normal left ventricular function undergoing cardiac surgery.
Nattachai Anantasit, John H Boyd, James A Russell, Christopher D Fjell, Samuel V Lichtenstein

J Thorac Cardiovasc Surg· May 2014

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A multibiomarker-based outcome risk stratification model for adult septic shock*.
Hector R Wong, Christopher J Lindsell, Ville Pettilä, Nuala J Meyer, Simone A Thair, Christopher D Fjell

Crit Care Med· April 2014

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Innate defense regulator peptide 1018 protects against perinatal brain injury.
Hayde Bolouri, Karin Sävman, Wei Wang, Anitha Thomas, Norbert Maurer, Christopher D Fjell

Ann Neurol· March 2014

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Synthetic cationic peptide IDR-1018 modulates human macrophage differentiation.
Olga M Pena, Nicole Afacan, Jelena Pistolic, Carol Chen, Laurence Madera, Christopher D Fjell

PLoS One· July 2013

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INMEX--a web-based tool for integrative meta-analysis of expression data.
Jianguo Xia, Christopher D Fjell, Matthew L Mayer, Olga M Pena, David S Wishart

Nucleic Acids Res· July 2013

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Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia.
Salman Ali, Aaron F Hirschfeld, Matthew L Mayer, Edgardo S Fortuno, Nathan Corbett, Christopher D Fjell

J Immunol· April 2013

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Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses.
Christoph J Blohmke, Matthew L Mayer, Anthony C Tang, Aaron F Hirschfeld, Christopher D Fjell

J Immunol· December 2012

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A systems biology approach to nutritional immunology - focus on innate immunity.
Nicole J Afacan, Christopher D Fjell, Robert E W Hancock

Mol Aspects Med· February 2012

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Designing antimicrobial peptides: form follows function.
Christopher D Fjell, Jan A Hiss, Robert E W Hancock, Gisbert Schneider

Nat Rev Drug Discov· December 2011

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Endotoxin tolerance represents a distinctive state of alternative polarization (M2) in human mononuclear cells.
Olga M Pena, Jelena Pistolic, Disha Raj, Christopher D Fjell, Robert E W Hancock

J Immunol· June 2011

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Optimization of antibacterial peptides by genetic algorithms and cheminformatics.
Christopher D Fjell, Håvard Jenssen, Warren A Cheung, Robert E W Hancock, Artem Cherkasov

Chem Biol Drug Des· January 2011

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Identification of novel antibacterial peptides by chemoinformatics and machine learning.
Christopher D Fjell, Håvard Jenssen, Kai Hilpert, Warren A Cheung, Nelly Panté

J Med Chem· April 2009

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Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs.
Artem Cherkasov, Kai Hilpert, Håvard Jenssen, Christopher D Fjell, Matt Waldbrook

ACS Chem Biol· January 2009

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Screening and characterization of surface-tethered cationic peptides for antimicrobial activity.
Kai Hilpert, Melissa Elliott, Håvard Jenssen, Jason Kindrachuk, Christopher D Fjell

Chem Biol· January 2009

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Identification of novel host defense peptides and the absence of alpha-defensins in the bovine genome.
Christopher D Fjell, Håvard Jenssen, Patrick Fries, Palok Aich, Philip Griebel

Proteins· November 2008

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Short linear cationic antimicrobial peptides: screening, optimizing, and prediction.
Kai Hilpert, Christopher D Fjell, Artem Cherkasov

Methods Mol Biol· November 2008

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QSAR modeling and computer-aided design of antimicrobial peptides.
Håvard Jenssen, Christopher D Fjell, Artem Cherkasov, Robert E W Hancock

J Pept Sci· January 2008

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Evaluating different descriptors for model design of antimicrobial peptides with enhanced activity toward P. aeruginosa.
Håvard Jenssen, Tore Lejon, Kai Hilpert, Christopher D Fjell, Artem Cherkasov

Chem Biol Drug Des· August 2007

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