Publications by authors named "Christopher D Kane"

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The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections.
Mark R Hickman, David L Saunders, Catherine A Bigger, Christopher D Kane, Patrick L Iversen

PLoS Negl Trop Dis· March 2022

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Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus.
Travis K Warren, Christopher D Kane, Jay Wells, Kelly S Stuthman, Sean A Van Tongeren

Sci Rep· September 2021

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and Characterization of Tebipenem (TBP), an Orally Active Carbapenem, against Biothreat Pathogens.
Nicholas P Clayton, Akash Jain, Stephanie A Halasohoris, Lisa M Pysz, Sanae Lembirik, Christopher D Kane

Antimicrob Agents Chemother· May 2021

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Vinyl Sulfone-Based Inhibitors of Nonstructural Protein 2 Block the Replication of Venezuelan Equine Encephalitis Virus.
Huaisheng Zhang, Moeshia Harmon, Sheli R Radoshitzky, Veronica Soloveva, Christopher D Kane

ACS Med Chem Lett· November 2020

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Recent successes in therapeutics for Ebola virus disease: no time for complacency.
Patrick L Iversen, Christopher D Kane, Xiankun Zeng, Rekha G Panchal, Travis K Warren

Lancet Infect Dis· September 2020

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Early detection of Ebola virus proteins in peripheral blood mononuclear cells from infected mice.
Michael D Ward, Tara Kenny, Ernie Bruggeman, Christopher D Kane, Courtney L Morrell, Molly M Kane

Clin Proteomics· March 2020

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Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo.
Antonello Pessi, Sandra L Bixler, Veronica Soloveva, Sheli Radoshitzky, Cary Retterer, Christopher D Kane

Antiviral Res· November 2019

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Countering Zika Virus: The USAMRIID Response.
Robert G Lowen, Thomas M Bocan, Christopher D Kane, Lisa H Cazares, Krishna P Kota

Adv Exp Med Biol· November 2018

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African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo.
Darci R Smith, Thomas R Sprague, Bradley S Hollidge, Stephanie M Valdez, Susana L Padilla, Christopher D Kane

Am J Trop Med Hyg· February 2018

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Clinical Laboratory Values as Early Indicators of Ebola Virus Infection in Nonhuman Primates.
Ronald B Reisler, Chenggang Yu, Michael J Donofrio, Travis K Warren, Jay B Wells, Christopher D Kane

Emerg Infect Dis· August 2017

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Searching for Therapeutics Against Botulinum Neurotoxins: A True Challenge for Drug Discovery.
Allen J Duplantier, Christopher D Kane, Sina Bavari

Curr Top Med Chem· February 2017

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Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays.
Erkan Kiris, Jonathan E Nuss, Stephanie M Stanford, Laura M Wanner, Lisa Cazares, Christopher D Kane

PLoS One· April 2016

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Recent advances in botulinum neurotoxin inhibitor development.
Erkan Kiris, James C Burnett, Christopher D Kane, Sina Bavari

Curr Top Med Chem· July 2015

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Novel therapeutic uses and formulations of botulinum neurotoxins: a patent review (2012 - 2014).
Christopher D Kane, Jonathan E Nuss, Sina Bavari

Expert Opin Ther Pat· June 2015

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SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neurons.
Erkan Kiris, James C Burnett, Jonathan E Nuss, Laura M Wanner, Brian D Peyser, Christopher D Kane

Neurotox Res· May 2015

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A high content imaging assay for identification of Botulinum neurotoxin inhibitors.
Krishna P Kota, Veronica Soloveva, Laura M Wanner, Glenn Gomba, Erkan Kiris, Christopher D Kane

J Vis Exp· November 2014

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Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery.
Erkan Kiris, Krishna P Kota, James C Burnett, Veronica Soloveva, Christopher D Kane

Expert Rev Mol Diagn· March 2014

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Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis.
Gerd R Burmester, Michael E Weinblatt, Iain B McInnes, Duncan Porter, Olga Barbarash, Christopher D Kane

Ann Rheum Dis· September 2013

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Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists.
Agustin Casimiro-Garcia, Christopher F Bigge, Jo Ann Davis, Teresa Padalino, James Pulaski, Christopher D Kane

Bioorg Med Chem· October 2009

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The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding.
Omar L Francone, Meihua Tu, Lori J Royer, Jian Zhu, Kimberly Stevens, Christopher D Kane

J Lipid Res· March 2009

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Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivo.
Christopher D Kane, Kimberly A Stevens, James E Fischer, Mehrdad Haghpassand, Lori J Royer

Mol Pharmacol· February 2009

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Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.
Agustin Casimiro-Garcia, Christopher F Bigge, Jo Ann Davis, Teresa Padalino, James Pulaski, Christopher D Kane

Bioorg Med Chem· May 2008

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Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha.
Christopher D Kane, Omar L Francone, Kimberly A Stevens

Gene· October 2006

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Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences.
Ethan E Corcoran, James D Joseph, Justin A MacDonald, Christopher D Kane, Timothy A J Haystead

J Biol Chem· March 2003

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