Publications by authors named "Christopher D Spilling"

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The polyamino-isoprenyl enhancer NV716 enables the antibacterial activity of two families of multi-target inhibitors against the ESKAPEE bacterium .
Emma Forest, Jordan Lehoux, Alexandre Guy, Thierry Durand, Stéphane Audebert, Christopher D Spilling

mLife· June 2025

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Cyclophostin and Cyclipostins analogues counteract macrolide-induced resistance mediated by erm(41) in Mycobacterium abscessus.
Morgane Sarrazin, Isabelle Poncin, Patrick Fourquet, Stéphane Audebert, Luc Camoin, Christopher D Spilling

J Biomed Sci· December 2024

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Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis.
Sarah Barelier, Romain Avellan, Giri Raj Gnawali, Patrick Fourquet, Véronique Roig-Zamboni, Christopher D Spilling

FEBS J· March 2023

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Synthesis and Biological Characterization of Fluorescent Cyclipostins and Cyclophostin Analogues: New Insights for the Diagnosis of Mycobacterial-Related Diseases.
Morgane Sarrazin, Benjamin P Martin, Romain Avellan, Giri Raj Gnawali, Isabelle Poncin, Christopher D Spilling

ACS Infect Dis· December 2022

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Lipolytic enzymes inhibitors: A new way for antibacterial drugs discovery.
Jean-François Cavalier, Christopher D Spilling, Thierry Durand, Luc Camoin, Stéphane Canaan

Eur J Med Chem· January 2021

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Synthesis of Phosphonomethyl Tetrahydrofurans via the Mori-Tamaru Reaction of Phosphonodienes.
Rishi R Paudel, Jeremy N Ridenour, Nigam P Rath, Christopher D Spilling

Org Lett· May 2020

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Leaving Group Effects in a Series of Electrosprayed CHN Anthracene Derivatives.
Maha T Abutokaikah, Giri R Gnawali, Joseph W Frye, Curtis M Stump, John Tschampel, Christopher D Spilling

J Am Soc Mass Spectrom· November 2019

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Cyclipostins and Cyclophostin Analogues as Multitarget Inhibitors That Impair Growth of .
Abdeldjalil Madani, Jeremy N Ridenour, Benjamin P Martin, Rishi R Paudel, Anosha Abdul Basir, Christopher D Spilling

ACS Infect Dis· September 2019

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Synthesis of Phostones via the Palladium-Catalyzed Ring Opening of Epoxy Vinyl Phosphonates.
Giri Raj Gnawali, Nigam P Rath, Christopher D Spilling

J Org Chem· July 2019

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The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds.
Christopher D Spilling

Molecules· July 2019

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Cyclophostin and Cyclipostins analogues, new promising molecules to treat mycobacterial-related diseases.
Phuong Chi Nguyen, Abdeldjalil Madani, Pierre Santucci, Benjamin P Martin, Rishi R Paudel, Christopher D Spilling

Int J Antimicrob Agents· April 2018

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Cyclipostins and cyclophostin analogs inhibit the antigen 85C from both and .
Albertus Viljoen, Matthias Richard, Phuong Chi Nguyen, Patrick Fourquet, Luc Camoin, Christopher D Spilling

J Biol Chem· February 2018

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Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.
Phuong Chi Nguyen, Vincent Delorme, Anaïs Bénarouche, Benjamin P Martin, Rishi Paudel, Christopher D Spilling

Sci Rep· September 2017

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Enantioseparation of α-Hydroxyallylphosphonates and Phosphonoallylic Carbonate Derivatives on Chiral Stationary Phases Using Sequential UV, Polarimetric, and Refractive Index Detection.
Bruce C Hamper, Michael P Mannino, Melissa E Mueller, Liam T Harrison, Christopher D Spilling

Chirality· September 2016

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Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin.
Benjamin P Martin, Elena Vasilieva, Cynthia M Dupureur, Christopher D Spilling

Bioorg Med Chem· December 2015

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Synthesis of non-racemic α-hydroxyphosphonates via asymmetric phospho-aldol reaction.
Christopher D Spilling, Raj K Malla

Top Curr Chem· June 2015

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Trapping Hemiacetals with Phosphono Substituted Palladium π-Allyl Complexes for the Synthesis of Substituted Cyclic Ethers.
Nongnuch Sutivisedsak, Surendra Dawadi, Christopher D Spilling

Tetrahedron Lett· June 2015

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Rat hormone sensitive lipase inhibition by cyclipostins and their analogs.
Elena Vasilieva, Supratik Dutta, Raj K Malla, Benjamin P Martin, Christopher D Spilling

Bioorg Med Chem· March 2015

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A new class of salicylic acid derivatives for inhibiting YopH of Yersinia pestis.
Mahesh P Paudyal, Li Wu, Zhong-Yin Zhang, Christopher D Spilling, Chung F Wong

Bioorg Med Chem· December 2014

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Relay cross metathesis reactions of vinylphosphonates.
Raj K Malla, Jeremy N Ridenour, Christopher D Spilling

Beilstein J Org Chem· September 2014

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A Filtration System That Greatly Reduces Aluminum in Calcium Gluconate Injection, USP Used to Prepare Parenteral Nutrition Solutions.
Robert A Yokel, Wesley R Harris, Christopher D Spilling, Vasiliy P Abramov, Jason M Lone

J Pediatr Pharmacol Ther· July 2014

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Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry.
Erik L Regalado, Marisa C Kozlowski, John M Curto, Tobias Ritter, Michael G Campbell, Christopher D Spilling

Org Biomol Chem· April 2014

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Enantioselective inhibition of microbial lipolytic enzymes by nonracemic monocyclic enolphosphonate analogues of cyclophostin.
Vanessa Point, Raj K Malla, Frederic Carrière, Stéphane Canaan, Christopher D Spilling

J Med Chem· June 2013

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Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases.
Vanessa Point, Raj K Malla, Sadia Diomande, Benjamin P Martin, Vincent Delorme, Christopher D Spilling

J Med Chem· November 2012

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Synthesis and biological evaluation of purpurealidin E-derived marine sponge metabolites: aplysamine-2, aplyzanzine A, and suberedamines A and B.
Suresh K Kottakota, Dimitrios Evangelopoulos, Amani Alnimr, Sanjib Bhakta, Timothy D McHugh, Christopher D Spilling

J Nat Prod· June 2012

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