Publications by authors named "Christopher Earley"

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Adaptive spinal cord stimulation improves restless legs syndrome: Case report, literature review, and mechanistic hypothesis.
Marshall T Holland, Mena N Mekhail, Garrett Thrash, Tony George, Dave Mugan, Christopher J Earley

Sleep Med· October 2025

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On the mechanisms of dopamine receptor agonists in restless legs syndrome.
Sergi Ferré, Diego García-Borreguero, Christopher J Earley

Sleep· September 2025

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Locomotor activity depends on β-arrestin recruitment by the dopamine D receptor in the striatal D-D receptor heteromer.
Alexandra H Evans, Marc Ciruela-Jardí, William Rea, Bradley M Keegan, Marjorie R Levinstein, Christopher J Earley

Pharmacol Res· August 2025

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Imaging arterial and venous vessels using Iron Dextran enhanced multi-echo 3D gradient echo MRI at 7T.
Yinghao Li, Wei Li, Adrian Paez, Di Cao, Yuanqi Sun, Christopher Earley

NMR Biomed· December 2024

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Rethinking clinical trials in restless legs syndrome: A roadmap.
Diego Garcia-Borreguero, Jed Black, Christopher J Earley, Stephany Fulda, Birgit Högl

Sleep Med Rev· October 2024

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Brain Iron Dysregulation in Iron Deficiency Anemia-Related Restless Leg Syndrome Revealed by Neuron-Derived Extracellular Vesicles: A Case-Control Study.
Apostolos Manolopoulos, William York, Krishna Ananthu Pucha, Christopher J Earley, Dimitrios Kapogiannis

Ann Neurol· September 2024

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Clinical efficacy and safety of intravenous ferric carboxymaltose for treatment of restless legs syndrome: a multicenter, randomized, placebo-controlled clinical trial.
Christopher J Earley, Diego García-Borreguero, Mark Falone, John W Winkelman

Sleep· July 2024

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A randomized double-blind pilot study to evaluate the efficacy, safety, and tolerability of intravenous iron versus oral iron for the treatment of restless legs syndrome in patients with iron deficiency anemia.
Vanessa Short, Richard Allen, Christopher J Earley, Huzefa Bahrain, Stella Rineer

Am J Hematol· June 2024

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Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.
Barbara Schormair, Chen Zhao, Steven Bell, Maria Didriksen, Muhammad S Nawaz, Christopher J Earley

Nat Genet· June 2024

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On the optimization of 3D inflow-based vascular-space-occupancy (iVASO) MRI for the quantification of arterial cerebral blood volume (CBVa).
Chunming Gu, Yinghao Li, Di Cao, Xinyuan Miao, Adrian G Paez, Christopher J Earley

Magn Reson Med· May 2024

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Restless legs syndrome, neuroleptic-induced akathisia, and opioid-withdrawal restlessness: shared neuronal mechanisms?
Sergi Ferré, John W Winkelman, Diego García-Borreguero, Annabelle M Belcher, Joy H Chang, Christopher J Earley

Sleep· March 2024

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Ferric carboxymaltose effects on restless legs syndrome and on brain iron in patients with iron deficiency anemia.
Hyoeun Bae, Yong Won Cho, Keun Tae Kim, Xu Li, Christopher J Earley

Sleep Med· September 2023

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Brain-iron deficiency models of restless legs syndrome.
Christopher J Earley, Byron C Jones, Sergi Ferré

Exp Neurol· October 2022

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Functional and pharmacological role of the dopamine D receptor and its polymorphic variants.
Sergi Ferré, Annabelle M Belcher, Jordi Bonaventura, César Quiroz, Marta Sánchez-Soto, Christopher J Earley

Front Endocrinol (Lausanne)· October 2022

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A pilot study to understand the relationship between cortical arousals and leg movements during sleep.
Kanika Bansal, Javier Garcia, Cody Feltch, Christopher Earley, Ryan Robucci

Sci Rep· July 2022

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Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome.
Matilde S Rodrigues, Samira G Ferreira, César Quiroz, Christopher J Earley, Diego García-Borreguero

Molecules· February 2022

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The Safety and Efficacy of Pregabalin Add-on Therapy in Restless Legs Syndrome Patients.
Hyoeun Bae, Yong Won Cho, Keun Tae Kim, Richard P Allen, Christopher J Earley

Front Neurol· November 2021

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We need to do better: A systematic review and meta-analysis of diagnostic test accuracy of restless legs syndrome screening instruments.
Stephany Fulda, Richard P Allen, Christopher J Earley, Birgit Högl, Diego Garcia-Borreguero

Sleep Med Rev· August 2021

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Randomized, placebo-controlled trial of ferric carboxymaltose in restless legs syndrome patients with iron deficiency anemia.
Hyoeun Bae, Yong Won Cho, Keun Tae Kim, Richard P Allen, Christopher J Earley

Sleep Med· August 2021

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The Management of Restless Legs Syndrome: An Updated Algorithm.
Michael H Silber, Mark J Buchfuhrer, Christopher J Earley, Brian B Koo, Mauro Manconi

Mayo Clin Proc· July 2021

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Akathisia and Restless Legs Syndrome: Solving the Dopaminergic Paradox.
Sergi Ferré, Xavier Guitart, César Quiroz, William Rea, Celia García-Malo, Christopher J Earley

Sleep Med Clin· June 2021

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Pilot study: can machine learning analyses of movement discriminate between leg movements in sleep (LMS) with vs. without cortical arousals?
Amitanshu Jha, Nilanjan Banerjee, Cody Feltch, Ryan Robucci, Christopher J Earley

Sleep Breath· March 2021

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Developing a biomarker for restless leg syndrome using genome wide DNA methylation data.
Arunima Roy, Christopher J Earley, Richard P Allen, Zachary A Kaminsky

Sleep Med· February 2021

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Iron-deficiency and dopaminergic treatment effects on RLS-Like behaviors of an animal model with the brain iron deficiency pattern of the restless legs syndrome.
Richard P Allen, Christopher J Earley, Byron C Jones, Erica L Unger

Sleep Med· July 2020

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Evidence for communication of peripheral iron status to cerebrospinal fluid: clinical implications for therapeutic strategy.
James R Connor, Kari Duck, Stephanie Patton, Ian A Simpson, Lynn Marie Trotti, Christopher J Earley

Fluids Barriers CNS· April 2020

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