Publications by authors named "Christopher Hartl"

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Age-associated G-quadruplex accumulation and DDX5 loss shape chromatin landscapes in human astrocytes.
Andrey Tsvetkov, Vijay Kumar M J, Rocio Diaz Escarcega, Ellery Wheeler, Nitin Tandon, Christopher Hartl

Res Sq· November 2025

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Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD.
Michael J Gandal, Jillian R Haney, Brie Wamsley, Chloe X Yap, Sepideh Parhami, Christopher L Hartl

Nature· November 2022

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Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model.
Deanna M Marchionini, Jeh-Ping Liu, Alberto Ambesi-Impiombato, Kimberly Kerker, Kim Cirillo, Christopher Hartl

JCI Insight· October 2022

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Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility.
Christopher L Hartl, Gokul Ramaswami, William G Pembroke, Sandrine Muller, Greta Pintacuda

Nat Neurosci· September 2021

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Evolutionary conservation and divergence of the human brain transcriptome.
William G Pembroke, Christopher L Hartl, Daniel H Geschwind

Genome Biol· January 2021

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Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.
Rebecca L Walker, Gokul Ramaswami, Christopher Hartl, Nicholas Mancuso, Michael J Gandal

Cell· April 2020

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Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.
Rebecca L Walker, Gokul Ramaswami, Christopher Hartl, Nicholas Mancuso, Michael J Gandal

Cell· April 2020

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Clarifying the effect of library batch on extracellular RNA sequencing.
Christopher Hartl, Yuan Gao

Proc Natl Acad Sci U S A· January 2020

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Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.
Rebecca L Walker, Gokul Ramaswami, Christopher Hartl, Nicholas Mancuso, Michael J Gandal

Cell· October 2019

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Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.
Neelroop N Parikshak, Vivek Swarup, T Grant Belgard, Manuel Irimia, Gokul Ramaswami, Christopher Hartl

Nature· August 2018

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Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Jason Flannick, Christian Fuchsberger, Anubha Mahajan, Tanya M Teslovich, Vineeta Agarwala, Christopher Hartl

Sci Data· January 2018

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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Jason Flannick, Christian Fuchsberger, Anubha Mahajan, Tanya M Teslovich, Vineeta Agarwala, Christopher Hartl

Sci Data· December 2017

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A Low-Frequency Inactivating Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Alisa Manning, Heather M Highland, Jessica Gasser, Xueling Sim, Taru Tukiainen, Christopher Hartl

Diabetes· July 2017

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Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.
Neelroop N Parikshak, Vivek Swarup, T Grant Belgard, Manuel Irimia, Gokul Ramaswami, Christopher Hartl

Nature· December 2016

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The genetic architecture of type 2 diabetes.
Christian Fuchsberger, Jason Flannick, Tanya M Teslovich, Anubha Mahajan, Vineeta Agarwala, Christopher Hartl

Nature· August 2016

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From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline.
Geraldine A Van der Auwera, Mauricio O Carneiro, Christopher Hartl, Ryan Poplin, Guillermo Del Angel

Curr Protoc Bioinformatics· July 2016

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SMaSH: a benchmarking toolkit for human genome variant calling.
Ameet Talwalkar, Jesse Liptrap, Julie Newcomb, Christopher Hartl, Jonathan Terhorst

Bioinformatics· October 2014

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A framework for variation discovery and genotyping using next-generation DNA sequencing data.
Mark A DePristo, Eric Banks, Ryan Poplin, Kiran V Garimella, Jared R Maguire, Christopher Hartl

Nat Genet· May 2011

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