Publications by authors named "Christopher Heise"

Claim this Profile
T
The discovery and structural basis of two distinct state-dependent inhibitors of BamA.
Dawei Sun, Kelly M Storek, Dimitry Tegunov, Ying Yang, Christopher P Arthur, Christopher E Heise

Nat Commun· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lipid Tales: Optimizing Arylomycin Membrane Anchors.
Michael F T Koehler, Yi-Chen Chen, Yongsheng Chen, Yuan Chen, James J Crawford, Christopher E Heise

ACS Med Chem Lett· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimized arylomycins are a new class of Gram-negative antibiotics.
Peter A Smith, Michael F T Koehler, Hany S Girgis, Donghong Yan, Yongsheng Chen, Christopher E Heise

Nature· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models.
Christopher Heise, Jonathan M Preuss, Jan C Schroeder, Chiara R Battaglia, Jonas Kolibius

Front Mol Neurosci· June 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.
Christopher Heise, Elham Taha, Luca Murru, Luisa Ponzoni, Angela Cattaneo

Cereb Cortex· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Epilepsy and intellectual disability linked protein Shrm4 interaction with GABARs shapes inhibitory neurotransmission.
Jonathan Zapata, Edoardo Moretto, Saad Hannan, Luca Murru, Anna Longatti, Christopher Heise

Nat Commun· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase.
J Hiroshi Morisaki, Peter A Smith, Shailesh V Date, Kimberly K Kajihara, Chau Linda Truong, Christopher E Heise

mBio· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors.
Wendy Lee, James J Crawford, Ignacio Aliagas, Lesley J Murray, Suzanne Tay, Christopher E Heise

Bioorg Med Chem Lett· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window.
Joachim Rudolph, Lesley J Murray, Chudi O Ndubaku, Thomas O'Brien, Elizabeth Blackwood, Christopher E Heise

J Med Chem· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.
Christopher Heise, Jan C Schroeder, Michael Schoen, Sonja Halbedl, Dominik Reim

Front Cell Neurosci· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The differential role of cortical protein synthesis in taste memory formation and persistence.
David Levitan, Shunit Gal-Ben-Ari, Christopher Heise, Tali Rosenberg, Alina Elkobi

NPJ Sci Learn· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.
Chudi O Ndubaku, James J Crawford, Joy Drobnick, Ignacio Aliagas, David Campbell, Christopher E Heise

ACS Med Chem Lett· December 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Daniel J Burdick, Shumei Wang, Christopher Heise, Borlan Pan, Jake Drummond

Bioorg Med Chem Lett· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors.
James J Crawford, Wendy Lee, Ignacio Aliagas, Simon Mathieu, Klaus P Hoeflich, Christopher E Heise

J Med Chem· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series.
Joachim Rudolph, Ignacio Aliagas, James J Crawford, Simon Mathieu, Wendy Lee, Christopher Heise

ACS Med Chem Lett· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hyaluronan-based extracellular matrix under conditions of homeostatic plasticity.
Juan Carlos Valenzuela, Christopher Heise, Gilbert Franken, Jeet Singh, Barbara Schweitzer

Philos Trans R Soc Lond B Biol Sci· October 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phosphorylation of neuronal Lysine-Specific Demethylase 1LSD1/KDM1A impairs transcriptional repression by regulating interaction with CoREST and histone deacetylases HDAC1/2.
Emanuela Toffolo, Francesco Rusconi, Leda Paganini, Marcello Tortorici, Simona Pilotto, Christopher Heise

J Neurochem· March 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons.
Christopher Heise, Fabrizio Gardoni, Lorenza Culotta, Monica di Luca, Chiara Verpelli

Front Cell Neurosci· March 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Back pocket flexibility provides group II p21-activated kinase (PAK) selectivity for type I 1/2 kinase inhibitors.
Steven T Staben, Jianwen A Feng, Karen Lyle, Marcia Belvin, Jason Boggs, Christopher Heise

J Med Chem· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutations of the synapse genes and intellectual disability syndromes.
Chiara Verpelli, Caterina Montani, Cinzia Vicidomini, Christopher Heise, Carlo Sala

Eur J Pharmacol· November 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells.
Chiara Verpelli, Luigi Carlessi, Giulia Bechi, Elena Fusar Poli, Daniel Orellana, Christopher Heise

Front Cell Neurosci· October 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability.
Benjamin E L Lauffer, Robert Mintzer, Rina Fong, Susmith Mukund, Christine Tam, Christopher E Heise

J Biol Chem· September 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6.
Christopher E Heise, Jeremy Murray, Katherine E Augustyn, Brandon Bravo, Preeti Chugha

PLoS One· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C.
Robert Mintzer, Sreemathy Ramaswamy, Kinjalkumar Shah, Rami N Hannoush, Christine D Pozniak, Christopher E Heise

PLoS One· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Case studies of minimizing nonspecific inhibitors in HTS campaigns that use assay-ready plates.
Yichin Liu, Maureen H Beresini, Adam Johnson, Robert Mintzer, Kinjalkumar Shah, Christopher E Heise

J Biomol Screen· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis