Publications by authors named "Christopher Lepsy"

Claim this Profile
S
Staining Triad: A fully automated and zero-waste flow cytometry staining system fostering the 3R to 4R transition.
Santosh Dhule, Eric Corriveau, Christopher Lepsy, Sophie Tourdot

SLAS Technol· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of a novel anti-PEG antibody assay enabling investigation of potential immunogenicity triggered by the PEG moiety of biotherapeutics.
Lisa Dyleski, Ying Wang, Elena Seletskaia, Lee Walus, Teresa Caiazzo, Christopher Lepsy

J Immunol Methods· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antidrug antibodies to adalimumab do not associate with immunologically related adverse events.
Sophie Tourdot, Maria-Dolores Vazquez-Abad, Donna S Cox, Chun-Hua Cai, Karen Wang, Christopher Lepsy

Front Immunol· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Addressing Domain Specificity in the Development of a Cell-Based Binding Assay for the Detection of Neutralizing Antibodies Against a CD47xPD-L1 Bispecific Antibody.
Michael Luong, Ying Wang, Brianna B Donnelly, Christopher Lepsy

AAPS J· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Determination of Anti-drug Antibody Affinity in Clinical Study Samples Provides a Tool for Evaluation of Immune Response Maturation.
Alison Joyce, Christopher Shea, Zhiping You, Boris Gorovits, Christopher Lepsy

AAPS J· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antitumor Necrosis Factor-like Ligand 1A Therapy Targets Tissue Inflammation and Fibrosis Pathways and Reduces Gut Pathobionts in Ulcerative Colitis.
Mina Hassan-Zahraee, Zhan Ye, Li Xi, Mary Lynn Baniecki, Xingpeng Li, Christopher Lepsy

Inflamm Bowel Dis· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Blocking TNF signaling may save lives in COVID-19 infection.
Vitaly Ablamunits, Christopher Lepsy

Mol Biol Rep· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study.
Silvio Danese, Maria Klopocka, Ellen J Scherl, Jacek Romatowski, Jessica R Allegretti, Christopher Lepsy

Clin Gastroenterol Hepatol· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fit-for-Purpose Validation and Establishment of Assay Acceptance and Reporting Criteria of Dendritic Cell Activation Assay Contributing to the Assessment of Immunogenicity Risk.
Dilki Wickramarachchi, Gregory Steeno, Zhiping You, Saleem Shaik, Christopher Lepsy

AAPS J· August 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
First-in-human, randomized dose-escalation study of the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of PF-06480605 in healthy subjects.
Christopher Banfield, Dan Rudin, Indranil Bhattacharya, Kosalaram Goteti, Gang Li, Christopher Lepsy

Br J Clin Pharmacol· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Anti-drug Antibody Assay Conditions Significantly Impact Assay Screen and Confirmatory Cut-Points.
Boris Gorovits, Ying Wang, Liang Zhu, Marcela Araya, John Kamerud, Christopher Lepsy

AAPS J· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mucosal Gene Expression in Pediatric and Adult Patients With Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis.
Jodie Ouahed, William Gordon, James B Canavan, Huanyu Zhou, Sarah Du, Christopher Lepsy

Inflamm Bowel Dis· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation.
Mengmeng Wang, Amanda K Kussrow, Mireia Fernandez Ocana, Jeffrey R Chabot, Christopher S Lepsy

Br J Pharmacol· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanism-based pharmacokinetic/pharmacodynamic modeling of rat prefrontal cortical dopamine response to dual acting norepinephrine reuptake inhibitor and 5-HT1A partial agonist.
Cheryl Shuang-wu Li, Liming Zhang, Taraneh Haske, Amy Dounay, David Gray, Christopher Lepsy

AAPS J· June 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A universal strategy for development of a method for absolute quantification of therapeutic monoclonal antibodies in biological matrices using differential dimethyl labeling coupled with ultra performance liquid chromatography-tandem mass spectrometry.
Chengjie Ji, Nalini Sadagopan, Yizhong Zhang, Christopher Lepsy

Anal Chem· November 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The development and validation of a computational model to predict rat liver microsomal clearance.
Cheng Chang, David B Duignan, Kjell D Johnson, Pil H Lee, George S Cowan, Christopher S Lepsy

J Pharm Sci· August 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development and validation of an LC-MS/MS method for quantification of cyclic guanosine 3',5'-monophosphate (cGMP) in clinical applications: a comparison with a EIA method.
Yanhua Zhang, Dawn Dufield, Jon Klover, Wenlin Li, Gabriella Szekely-Klepser, Christopher Lepsy

J Chromatogr B Analyt Technol Biomed Life Sci· February 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Diethylation labeling combined with UPLC/MS/MS for simultaneous determination of a panel of monoamine neurotransmitters in rat prefrontal cortex microdialysates.
Chengjie Ji, Wenlin Li, Xiao-Dan Ren, Ayman F El-Kattan, Rouba Kozak, Christopher Lepsy

Anal Chem· December 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry.
Na Li, Olga V Nemirovskiy, Yiqun Zhang, Haodan Yuan, Jianming Mo, Christopher Lepsy

Anal Biochem· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Implementation of an ADME enabling selection and visualization tool for drug discovery.
Chad L Stoner, Eric Gifford, Charles Stankovic, Christopher S Lepsy, Joanne Brodfuehrer

J Pharm Sci· May 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effects of organic anion, organic cation, and dipeptide transport inhibitors on cefdinir in the isolated perfused rat kidney.
Christopher S Lepsy, Robert J Guttendorf, Alan R Kugler, David E Smith

Antimicrob Agents Chemother· February 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis