Publications by authors named "Christopher Lines"

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Randomized, controlled, proof-of-concept trial of gefapixant for endometriosis-related pain.
Felipe Arbelaez, Hee-Koung Joeng, Azher Hussain, Sheila Sunga, Yanfen Guan, Christopher Lines

Fertil Steril· February 2025

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Phase advance of bedtimes in Alzheimer's disease.
Donald L Bliwise, Ting-Chuan Wang, Vladimir Svetnik, Gary Zammit, Peining Tao, Christopher Lines

Sleep· November 2023

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Progression from Prodromal Alzheimer's Disease to Mild Alzheimer's Disease Dementia in the Verubecestat APECS Study: Adjudicating Diagnostic Transitions.
Tiffini Voss, James Kost, Swati Pal Mercer, Christine Furtek, Christopher Randolph, Christopher Lines

J Alzheimers Dis· March 2023

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Comparison of polysomnography in people with Alzheimer's disease and insomnia versus non-demented elderly people with insomnia.
Peining Tao, Vladimir Svetnik, Donald L Bliwise, Gary Zammit, Christopher Lines

Sleep Med· January 2023

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Effects of Bedtime Dosing With Suvorexant and Zolpidem on Balance and Psychomotor Performance in Healthy Elderly Participants During the Night and in the Morning.
Hubert Bland, Xiaodong Li, Eric Mangin, Ka Lai Yee, Christopher Lines

J Clin Psychopharmacol· December 2021

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Pilot evaluation of a consumer wearable device to assess sleep in a clinical polysomnography trial of suvorexant for treating insomnia in patients with Alzheimer's disease.
Vladimir Svetnik, Ting-Chuan Wang, Paulette Ceesay, Ellen Snyder, Omar Ceren, Christopher Lines

J Sleep Res· December 2021

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Use of the single-item Patient Global Impression-Severity scale as a self-reported assessment of insomnia severity.
Ellen S Snyder, Peining Tao, Vladimir Svetnik, Christopher Lines, W Joseph Herring

J Sleep Res· February 2021

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BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain.
Cyrille Sur, James Kost, David Scott, Katarzyna Adamczuk, Nick C Fox, Christopher Lines

Brain· December 2020

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Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease.
Alette M Wessels, Christopher Lines, Robert A Stern, James Kost, Tiffini Voss

Alzheimers Dement· November 2020

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How well can a large number of polysomnography sleep measures predict subjective sleep quality in insomnia patients?
Vladimir Svetnik, Ellen S Snyder, Peining Tao, Thomas Roth, Christopher Lines

Sleep Med· March 2020

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Polysomnographic assessment of suvorexant in patients with probable Alzheimer's disease dementia and insomnia: a randomized trial.
W Joseph Herring, Paulette Ceesay, Ellen Snyder, Donald Bliwise, Kerry Budd, Christopher Lines

Alzheimers Dement· March 2020

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Further analyses of the safety of verubecestat in the phase 3 EPOCH trial of mild-to-moderate Alzheimer's disease.
Michael F Egan, Yuki Mukai, Tiffini Voss, James Kost, Julie Stone, Christopher Lines

Alzheimers Res Ther· August 2019

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Effects of suvorexant on the Insomnia Severity Index in patients with insomnia: analysis of pooled phase 3 data.
W Joseph Herring, Kathryn M Connor, Ellen Snyder, Duane B Snavely, Charles M Morin, Christopher Lines

Sleep Med· April 2019

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A Phase Ib Randomized Controlled Study to Evaluate the Effectiveness of a Single-Dose of the NR2B Selective N-Methyl-D-Aspartate Antagonist MK-0657 on Levodopa-Induced Dyskinesias and Motor Symptoms in Patients With Parkinson Disease.
W Joseph Herring, Christopher Assaid, Kerry Budd, Ryan Vargo, Ralph S Mazenko, Christopher Lines

Clin Neuropharmacol· June 2018

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Insight Into Reduction of Wakefulness by Suvorexant in Patients With Insomnia: Analysis of Wake Bouts.
Vladimir Svetnik, Ellen S Snyder, Peining Tao, Thomas E Scammell, Thomas Roth, Christopher Lines

Sleep· January 2018

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Phase II Proof-of-Concept Trial of the Orexin Receptor Antagonist Filorexant (MK-6096) in Patients with Major Depressive Disorder.
Kathryn M Connor, Paulette Ceesay, Jill Hutzelmann, Duane Snavely, Andrew D Krystal, Christopher Lines

Int J Neuropsychopharmacol· August 2017

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Suvorexant in Elderly Patients with Insomnia: Pooled Analyses of Data from Phase III Randomized Controlled Clinical Trials.
W Joseph Herring, Kathryn M Connor, Ellen Snyder, Duane B Snavely, Ying Zhang, Christopher Lines

Am J Geriatr Psychiatry· July 2017

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Clinical profile of suvorexant for the treatment of insomnia over 3 months in women and men: subgroup analysis of pooled phase-3 data.
W Joseph Herring, Kathryn M Connor, Ellen Snyder, Duane B Snavely, Ying Zhang, Christopher Lines

Psychopharmacology (Berl)· June 2017

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Randomized trial of preladenant, given as monotherapy, in patients with early Parkinson disease.
Fabrizio Stocchi, Olivier Rascol, Robert A Hauser, Susan Huyck, Anjela Tzontcheva, Christopher Lines

Neurology· June 2017

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EEG spectral analysis of NREM sleep in a large sample of patients with insomnia and good sleepers: effects of age, sex and part of the night.
Vladimir Svetnik, Ellen S Snyder, Junshui Ma, Peining Tao, Christopher Lines

J Sleep Res· February 2017

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Suvorexant in Patients with Insomnia: Pooled Analyses of Three-Month Data from Phase-3 Randomized Controlled Clinical Trials.
W Joseph Herring, Kathleen M Connor, Ellen Snyder, Duane B Snavely, Ying Zhang, Christopher Lines

J Clin Sleep Med· September 2016

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Effects of suvorexant on sleep architecture and power spectral profile in patients with insomnia: analysis of pooled phase 3 data.
Ellen Snyder, Junshui Ma, Vladimir Svetnik, Kathryn M Connor, Christopher Lines

Sleep Med· March 2016

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Randomized controlled trial of the CGRP receptor antagonist telcagepant for prevention of headache in women with perimenstrual migraine.
Tony W Ho, Andrew P Ho, Yang Joy Ge, Christopher Assaid, Regina Gottwald, Christopher Lines

Cephalalgia· February 2016

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Effects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea.
Hong Sun, John Palcza, Deborah Card, Adrianna Gipson, Russell Rosenberg, Christopher Lines

J Clin Sleep Med· January 2016

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Preladenant as an Adjunctive Therapy With Levodopa in Parkinson Disease: Two Randomized Clinical Trials and Lessons Learned.
Robert A Hauser, Fabrizio Stocchi, Olivier Rascol, Susan B Huyck, Rachel Capece, Christopher Lines

JAMA Neurol· December 2015

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