Publications by authors named "Deborah Card"

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Effects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea.
Hong Sun, John Palcza, Deborah Card, Adrianna Gipson, Russell Rosenberg

J Clin Sleep Med· January 2016

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Antifungal spectrum, in vivo efficacy, and structure-activity relationship of ilicicolin h.
Sheo B Singh, Weiguo Liu, Xiaohua Li, Tom Chen, Ali Shafiee, Deborah Card

ACS Med Chem Lett· October 2012

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Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells.
Deborah A Greer Card, Pratibha B Hebbar, Leping Li, Kevin W Trotter, Yoshihiro Komatsu

Mol Cell Biol· October 2008

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SAR studies of 3-arylpropionic acids as potent and selective agonists of sphingosine-1-phosphate receptor-1 (S1P1) with enhanced pharmacokinetic properties.
Lin Yan, Pei Huo, Jeffrey J Hale, Sander G Mills, Richard Hajdu, Deborah Card

Bioorg Med Chem Lett· February 2007

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2-Aryl(pyrrolidin-4-yl)acetic acids are potent agonists of sphingosine-1-phosphate (S1P) receptors.
Lin Yan, Richard Budhu, Pei Huo, Christopher L Lynch, Jeffrey J Hale, Deborah Card

Bioorg Med Chem Lett· July 2006

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Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes.
Lin Yan, Pei Huo, George Doherty, Lesile Toth, Jeffrey J Hale, Deborah Card

Bioorg Med Chem Lett· July 2006

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2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists.
Vincent J Colandrea, Irene E Legiec, Pei Huo, Lin Yan, Jeffrey J Hale, Deborah Card

Bioorg Med Chem Lett· June 2006

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Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3.
Zhen Li, Weirong Chen, Jeffrey J Hale, Christopher L Lynch, Sander G Mills, Deborah Card

J Med Chem· October 2005

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A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists.
Jeffrey J Hale, Christopher L Lynch, William Neway, Sander G Mills, Richard Hajdu, Deborah Card

J Med Chem· December 2004

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Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors.
Lin Yan, Jeffrey J Hale, Christopher L Lynch, Richard Budhu, Amy Gentry, Deborah Card

Bioorg Med Chem Lett· October 2004

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Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720.
Jeffrey J Hale, Lin Yan, William E Neway, Richard Hajdu, James D Bergstrom, Deborah Card

Bioorg Med Chem· September 2004

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The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists.
Jeffrey J Hale, George Doherty, Leslie Toth, Zhen Li, Sander G Mills, Deborah Card

Bioorg Med Chem Lett· July 2004

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Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists.
Jeffrey J Hale, George Doherty, Leslie Toth, Sander G Mills, Richard Hajdu, Deborah Card

Bioorg Med Chem Lett· July 2004

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Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720.
Jeffrey J Hale, William Neway, Sander G Mills, Richard Hajdu, Carol Ann Keohane, Deborah Card

Bioorg Med Chem Lett· June 2004

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.
Suzanne Mandala, Richard Hajdu, James Bergstrom, Elizabeth Quackenbush, Jenny Xie, Deborah Card

Science· April 2002

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