Publications by authors named "Sander G Mills"

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Design, synthesis, and biological evaluation of aminopyrazine derivatives as inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
Songnian Lin, Sunita Malkani, Matthew Lombardo, Lihu Yang, Sander G Mills

Bioorg Med Chem Lett· November 2015

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2-[(3aR,4R,5S,7aS)-5-{(1S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxyethoxy}-4-(2-methylphenyl)octahydro-2H-isoindol-2-yl]-1,3-oxazol-4(5H)-one: a potent human NK1 receptor antagonist with multiple clearance pathways.
Andrew J Kassick, Jinlong Jiang, Jaime Bunda, David Wilson, Jianming Bao, Sander G Mills

J Med Chem· July 2013

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Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics.
Haifeng Tang, Shawn P Walsh, Yan Yan, Reynalda K de Jesus, Aurash Shahripour, Sander G Mills

ACS Med Chem Lett· May 2012

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Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist.
Alexander Pasternak, Zhe Feng, Reynalda de Jesus, Zhixiong Ye, Shuwen He, Sander G Mills

ACS Med Chem Lett· April 2012

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3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists.
Shawn P Walsh, Alexandra Severino, Changyou Zhou, Jiafang He, Gui-Bai Liang, Sander G Mills

Bioorg Med Chem Lett· June 2011

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Spiroimidazolidinone NPC1L1 inhibitors. Part 2: structure-activity studies and in vivo efficacy.
Kobporn L Howell, Robert J DeVita, Margarita Garcia-Calvo, Roger D Meurer, JeanMarie Lisnock, Sander G Mills

Bioorg Med Chem Lett· December 2010

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Fused tricyclic pyrrolizinones that exhibit pseudo-irreversible blockade of the NK1 receptor.
Gregori J Morriello, Gary Chicchi, Tricia Johnson, Sander G Mills, Julie Demartino

Bioorg Med Chem Lett· October 2010

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Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities.
Haifeng Tang, Yan Yan, Zhe Feng, Reynalda K de Jesus, Lihu Yang, Sander G Mills

Bioorg Med Chem Lett· October 2010

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Tetrahydroindolizinone NK1 antagonists.
Jianming Bao, Huagang Lu, Gregori J Morriello, Emma J Carlson, Alan Wheeldon, Sander G Mills

Bioorg Med Chem Lett· April 2010

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Substituted fused bicyclic pyrrolizinones as potent, orally bioavailable hNK1 antagonists.
Gregori J Morriello, Sander G Mills, Tricia Johnson, Mikhail Reibarkh, Gary Chicchi

Bioorg Med Chem Lett· March 2010

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Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists.
Changyou Zhou, Cheng Tang, Eric Chang, Min Ge, Songnian Lin, Sander G Mills

Bioorg Med Chem Lett· February 2010

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Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists.
Alexander Pasternak, Stephen D Goble, Reynalda K deJesus, Donna L Hreniuk, Christine C Chung, Sander G Mills

Bioorg Med Chem Lett· November 2009

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Disubstituted pyrimidines as Lck inhibitors.
Julianne A Hunt, Richard T Beresis, Joung L Goulet, Mark A Holmes, Xinfang J Hong, Sander G Mills

Bioorg Med Chem Lett· September 2009

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Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
Songnian Lin, Matthew Lombardo, Sunita Malkani, Jeffrey J Hale, Sander G Mills

Bioorg Med Chem Lett· June 2009

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Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists.
Jinlong Jiang, Jaime L Bunda, Geoge A Doss, Gary G Chicchi, Marc M Kurtz, Sander G Mills

J Med Chem· May 2009

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Design, synthesis, and structure-activity relationship of novel CCR2 antagonists.
Shankaran Kothandaraman, Karla L Donnely, Gabor Butora, Richard Jiao, Alexander Pasternak, Sander G Mills

Bioorg Med Chem Lett· March 2009

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Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice.
Carina P Tan, Yue Feng, Yun-Ping Zhou, George J Eiermann, Aleksandr Petrov, Sander G Mills

Diabetes· August 2008

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Fused bicyclic pyrrolizinones as new scaffolds for human NK1 antagonists.
Gregori J Morriello, Robert J Devita, Sander G Mills, Jonathan R Young, Peter Lin

Bioorg Med Chem· March 2008

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Potent heteroarylpiperidine and carboxyphenylpiperidine 1-alkyl-cyclopentane carboxamide CCR2 antagonists.
Alexander Pasternak, Stephen D Goble, Pasquale P Vicario, Jerry Di Salvo, Julia M Ayala, Sander G Mills

Bioorg Med Chem Lett· February 2008

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Conformational studies of 3-amino-1-alkyl-cyclopentane carboxamide CCR2 antagonists leading to new spirocyclic antagonists.
Alexander Pasternak, Stephen D Goble, George A Doss, Nancy N Tsou, Gabor Butora, Sander G Mills

Bioorg Med Chem Lett· February 2008

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Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents.
Lauren P Shearman, D Sloan Stribling, Ramon E Camacho, Kimberly M Rosko, Junying Wang, Sander G Mills

Eur J Pharmacol· January 2008

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Pyrrolidine-carboxamides and oxadiazoles as potent hNK1 antagonists.
Jonathan R Young, Ronsar Eid, Cherilyn Turner, Robert J DeVita, Marc M Kurtz, Sander G Mills

Bioorg Med Chem Lett· October 2007

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The discovery of potent, selective, and orally bioavailable hNK1 antagonists derived from pyrrolidine.
Peter Lin, Lehua Chang, Robert J Devita, Jonathan R Young, Ronsar Eid, Sander G Mills

Bioorg Med Chem Lett· September 2007

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CCR5 blockade modulates inflammation and alloimmunity in primates.
Carsten Schröder, Richard N Pierson, Bao-Ngoc H Nguyen, Douglas W Kawka, Laurence B Peterson, Sander G Mills

J Immunol· August 2007

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Discovery of 3-piperidinyl-1-cyclopentanecarboxamide as a novel scaffold for highly potent CC chemokine receptor 2 antagonists.
Lihu Yang, Gabor Butora, Richard X Jiao, Alex Pasternak, Changyou Zhou, Sander G Mills

J Med Chem· May 2007

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