Publications by authors named "Christopher Pargellis"

Claim this Profile
D
Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Pier F Cirillo, Eugene R Hickey, Neil Moss, Steffen Breitfelder, Raj Betageri, Christopher A Pargellis

Bioorg Med Chem Lett· May 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling.
Lore M Gruenbaum, Racheline Schwartz, Joseph R Woska, Rodney P DeLeon, Gregory W Peet, Christopher A Pargellis

Biochem Pharmacol· February 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site.
Neil Moss, Steffen Breitfelder, Raj Betageri, Pier F Cirillo, Tazmeen Fadra, Christopher A Pargellis

Bioorg Med Chem Lett· August 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.
Jiang-Ping Wu, Ji Wang, Asitha Abeywardane, Denise Andersen, Michel Emmanuel, Christopher Pargellis

Bioorg Med Chem Lett· August 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and optimization of p38 inhibitors via computer-assisted drug design.
Daniel R Goldberg, Ming-Hong Hao, Kevin C Qian, Alan D Swinamer, Donghong A Gao, Christopher Pargellis

J Med Chem· August 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular basis of MAPK-activated protein kinase 2:p38 assembly.
Andre White, Christopher A Pargellis, Joey M Studts, Brian G Werneburg, Bennett T Farmer

Proc Natl Acad Sci U S A· April 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and characterization of a substrate selective p38alpha inhibitor.
Walter Davidson, Lee Frego, Gregory W Peet, Rachel R Kroe, Mark E Labadia, Christopher Pargellis

Biochemistry· September 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Catalysis and function of the p38 alpha.MK2a signaling complex.
Susan M Lukas, Rachel R Kroe, Jessi Wildeson, Gregory W Peet, Lee Frego, Christopher A Pargellis

Biochemistry· August 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors.
Rachel R Kroe, John Regan, Al Proto, Gregory W Peet, Tapon Roy, Christopher A Pargellis

J Med Chem· October 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).
John Regan, Alison Capolino, Pier F Cirillo, Thomas Gilmore, Anne G Graham, Christopher A Pargellis

J Med Chem· October 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The kinetics of binding to p38MAP kinase by analogues of BIRB 796.
John Regan, Christopher A Pargellis, Pier F Cirillo, Thomas Gilmore, Eugene R Hickey

Bioorg Med Chem Lett· September 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis.
Christopher Pargellis, John Regan

Curr Opin Investig Drugs· May 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The non-diaryl heterocycle classes of p38 MAP kinase inhibitors.
Pier F Cirillo, Christopher Pargellis, John Regan

Curr Top Med Chem· September 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.
Christopher Pargellis, Liang Tong, Laurie Churchill, Pier F Cirillo, Thomas Gilmore

Nat Struct Biol· April 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis