Publications by authors named "Christopher Tuggle"

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Construction of a Multitissue Cell Atlas Reveals Cell-Type-Specific Regulation of Molecular and Complex Phenotypes in Pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Christopher K Tuggle

Adv Sci (Weinh)· November 2025

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A pig with functional human immunity.
Christopher K Tuggle, Crystal L Loving, Beau R Webber

Nat Biomed Eng· October 2025

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Pig models reveal the interplay between fatty acids and cytokines in skeletal muscle.
Fernanda Nery Ciconello, Christopher Keith Tuggle, Julia Dezen Gomes, Bruna Pereira Martins da Silva, Mariah de Castro Durval

Sci Rep· June 2025

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The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project.
Lingzhao Fang, Jinyan Teng, Qing Lin, Zhonghao Bai, Shuli Liu, Christopher K Tuggle

Nat Genet· April 2025

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Comparative Genomics and Epigenomics of Transcriptional Regulation.
Huaijun Zhou, Emily Clark, Dailu Guan, Sandrine Lagarrigue, Lingzhao Fang, Christopher K Tuggle

Annu Rev Anim Biosci· February 2025

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Data reuse in agricultural genomics research: challenges and recommendations.
Alenka Hafner, Victoria DeLeo, Cecilia H Deng, Christine G Elsik, Damarius S Fleming, Christopher K Tuggle

Gigascience· January 2025

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Cell deconvolution-based integrated time-series network of whole blood transcriptome reveals systemic antiviral activities and cell-specific immunological changes against PRRSV infection.
Byeonghwi Lim, Chiwoong Lim, Min-Jae Jang, Young-Jun Seo, Do-Young Kim, Christopher K Tuggle

Vet Res· January 2025

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Definition of regulatory elements and transcription factors controlling porcine immune cell gene expression at single cell resolution using single nucleus ATAC-seq.
Pengxin Yang, Ryan Corbett, Lance Daharsh, Juber Herrera Uribe, Kristen A Byrne, Christopher Tuggle

Genomics· November 2024

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Building a FAIR data ecosystem for incorporating single-cell transcriptomics data into agricultural genome to phenome research.
Muskan Kapoor, Enrique Sapena Ventura, Amy Walsh, Alexey Sokolov, Nancy George, Christopher K Tuggle

Front Genet· November 2024

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EFFECT OF GENOTYPE AND AGE ON A DEFINED MICROBIOTA IN GNOTOBIOTIC SCID PIGLETS.
Katherine M Widmer, Faith Rahic-Seggerman, Ahlea Forster, Amanda Ahrens-Kress, Mary Sauer, Christopher K Tuggle

bioRxiv· September 2024

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Evidence of innate training in bovine γδ T cells following subcutaneous BCG administration.
Beulah Esther Rani Samuel, Fabian E Diaz, Teresia W Maina, Ryan J Corbett, Christopher K Tuggle

Front Immunol· August 2024

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The Ruminant Telomere-to-Telomere (RT2T) Consortium.
Theodore S Kalbfleisch, Stephanie D McKay, Brenda M Murdoch, David L Adelson, Diego Almansa-Villa, Christopher K Tuggle

Nat Genet· August 2024

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Current challenges and future of agricultural genomes to phenomes in the USA.
Christopher K Tuggle, Jennifer L Clarke, Brenda M Murdoch, Eric Lyons, Nicole M Scott

Genome Biol· January 2024

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A compendium of genetic regulatory effects across pig tissues.
Jinyan Teng, Yahui Gao, Hongwei Yin, Zhonghao Bai, Shuli Liu, Christopher K Tuggle

Nat Genet· January 2024

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Genetic analysis of the blood transcriptome of young healthy pigs to improve disease resilience.
Kyu-Sang Lim, Jian Cheng, Christopher Tuggle, Michael Dyck, PigGen Canada

Genet Sel Evol· December 2023

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Integrative profiling of gene expression and chromatin accessibility elucidates specific transcriptional networks in porcine neutrophils.
Juber Herrera-Uribe, Kyu-Sang Lim, Kristen A Byrne, Lance Daharsh, Haibo Liu, Christopher K Tuggle

Front Genet· May 2023

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Toward a data infrastructure for the Plant Cell Atlas.
Noah Fahlgren, Muskan Kapoor, Galabina Yordanova, Irene Papatheodorou, Jamie Waese, Christopher K Tuggle

Plant Physiol· January 2023

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Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells.
Jayne E Wiarda, Julian M Trachsel, Sathesh K Sivasankaran, Christopher K Tuggle, Crystal L Loving

Life Sci Alliance· October 2022

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Assessment of DNA methylation in porcine immune cells reveals novel regulatory elements associated with cell-specific gene expression and immune capacity traits.
Ryan J Corbett, Andrea M Luttman, Juber Herrera-Uribe, Haibo Liu, Nancy E Raney, Christopher K Tuggle

BMC Genomics· August 2022

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Ten simple rules to ruin a collaborative environment.
Carolyn J Lawrence-Dill, Robyn L Allscheid, Albert Boaitey, Todd Bauman, Edward S Buckler, Christopher K Tuggle

PLoS Comput Biol· April 2022

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Introduction to Mammalian Genome Special Issue: Mammalian Genetic Resources.
Steve D M Brown, Joseph H Nadeau, Sara Wells, Ann-Marie Mallon, Lydia Teboul, Christopher K Tuggle

Mamm Genome· March 2022

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The Agricultural Genome to Phenome Initiative (AG2PI): creating a shared vision across crop and livestock research communities.
Christopher K Tuggle, Jennifer Clarke, Jack C M Dekkers, David Ertl, Carolyn J Lawrence-Dill

Genome Biol· January 2022

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Associations of natural variation in the CD163 and other candidate genes on host response of nursery pigs to porcine reproductive and respiratory syndrome virus infection.
Qian Dong, Jenelle Dunkelberger, Kyu-Sang Lim, Joan K Lunney, Christopher K Tuggle

J Anim Sci· October 2021

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Pig genome functional annotation enhances the biological interpretation of complex traits and human disease.
Zhangyuan Pan, Yuelin Yao, Hongwei Yin, Zexi Cai, Ying Wang, Christopher K Tuggle

Nat Commun· October 2021

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Editorial: Functional Annotation of Animal Genomes.
Amanda Jane Chamberlain, Hans H Cheng, Elisabetta Giuffra, Christa Kuehn, Christopher K Tuggle

Front Genet· October 2021

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