Publications by authors named "Chuck Poole"

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A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors.
Christie A Schulte, David N Deaton, Elsie Diaz, Young Do, Robert T Gampe, Chuck Poole

Bioorg Med Chem Lett· September 2021

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The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure.
Rodolfo Cadilla, David N Deaton, Young Do, Patricia A Elkins, Daniela Ennulat, Chuck Poole

Bioorg Med Chem· December 2020

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The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.
David N Deaton, Young Do, Jason Holt, Michael R Jeune, H Fritz Kramer, Chuck Poole

Bioorg Med Chem· April 2019

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Optimizing Ligand Efficiency of Selective Androgen Receptor Modulators (SARMs).
Anthony L Handlon, Lee T Schaller, Lisa M Leesnitzer, Raymond V Merrihew, Chuck Poole

ACS Med Chem Lett· January 2016

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Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.
J David Becherer, Eric E Boros, Tiffany Y Carpenter, David J Cowan, David N Deaton, J Chuck Poole

J Med Chem· September 2015

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Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2.
Curt D Haffner, Stephen A Thomson, Yu Guo, Kimberly Petrov, Andrew Larkin, Chuck Poole

Bioorg Med Chem Lett· December 2010

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