Publications by authors named "Chunyun Du"

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Noncanonical pharmacological inhibition of the hERG K channel by a synthetic cannabinoid.
Hongwei Cheng, Catherine Upex, Chunyun Du, Caroline Copeland, Graeme Henderson

Biochem Pharmacol· August 2025

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Palmitoylation regulates the magnitude of HCN4-mediated currents in mammalian cells.
Samitha Dilini Congreve, Alice Main, Andrew S Butler, Xing Gao, Elaine Brown, Chunyun Du

Front Physiol· April 2023

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Identification through action potential clamp of proarrhythmic consequences of the short QT syndrome T618I hERG 'hotspot' mutation.
Chunyun Du, Henggui Zhang, Stephen C Harmer, Jules C Hancox

Biochem Biophys Res Commun· March 2022

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Investigation of the Effects of the Short QT Syndrome D172N Kir2.1 Mutation on Ventricular Action Potential Profile Using Dynamic Clamp.
Chunyun Du, Randall L Rasmusson, Glenna C Bett, Brandon Franks, Henggui Zhang

Front Pharmacol· January 2022

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Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant.
Ehab Al-Moubarak, Holly A Shiels, Yihong Zhang, Chunyun Du, Oliver Hanington

Cell Mol Life Sci· December 2021

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Impact of ambient relative humidity and acidity on chemical composition evolution for malonic acid/calcium nitrate mixed particles.
Chun-Yun Du, Wei Wang, Na Wang, Shu-Feng Pang, Yun-Hong Zhang

Chemosphere· August 2021

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Hygroscopicity measurement of sodium carbonate, β-alanine and internally mixed β-alanine/NaCO particles by ATR-FTIR.
Ping Yang, Hui Yang, Na Wang, Chunyun Du, Shufeng Pang

J Environ Sci (China)· January 2020

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Potent hERG channel inhibition by sarizotan, an investigative treatment for Rett Syndrome.
Hongwei Cheng, Chunyun Du, Yihong Zhang, Andrew F James, Christopher E Dempsey

J Mol Cell Cardiol· October 2019

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Structural implications of hERG K channel block by a high-affinity minimally structured blocker.
Matthew V Helliwell, Yihong Zhang, Aziza El Harchi, Chunyun Du, Jules C Hancox

J Biol Chem· May 2018

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Emerging therapeutic targets in the short QT syndrome.
Jules C Hancox, Dominic G Whittaker, Chunyun Du, A Graham Stuart, Henggui Zhang

Expert Opin Ther Targets· May 2018

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Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
Jennifer Batson, Hamish D Toop, Clara Redondo, Roya Babaei-Jadidi, Apirat Chaikuad, Chunyun Du

ACS Chem Biol· March 2017

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Modification of KCNH2-encoded cardiac potassium channels by KCNE1 polymorphism.
Jules C Hancox, Chunyun Du, Aziza El Harchi, Henggui Zhang

Circ J· May 2015

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Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration.
Dario Melgari, Chunyun Du, Aziza El Harchi, Yihong Zhang, Jules C Hancox

Physiol Rep· October 2014

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Ranolazine inhibition of hERG potassium channels: drug-pore interactions and reduced potency against inactivation mutants.
Chunyun Du, Yihong Zhang, Aziza El Harchi, Christopher E Dempsey, Jules C Hancox

J Mol Cell Cardiol· September 2014

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A novel genetic modifier for clarithromycin-related cardiac arrhythmia risk?
Jules C Hancox, Chunyun Du, Aziza El Harchi, Adrian Baranchuk, Henggui Zhang

Ther Adv Infect Dis· April 2014

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Modification by KCNE1 variants of the hERG potassium channel response to premature stimulation and to pharmacological inhibition.
Chunyun Du, Aziza El Harchi, Henggui Zhang, Jules C Hancox

Physiol Rep· November 2013

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Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD.
Melissa V Gammons, Oleg Fedorov, David Ivison, Chunyun Du, Tamsyn Clark

Invest Ophthalmol Vis Sci· September 2013

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High potency inhibition of hERG potassium channels by the sodium-calcium exchange inhibitor KB-R7943.
Hongwei Cheng, Yihong Zhang, Chunyun Du, Christopher E Dempsey, Jules C Hancox

Br J Pharmacol· April 2012

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[Changes of heart rate variability and impairment of learning and memory induced by cerebral ischemia/reperfusion in rats].
Dong Li, Chun-Yun DU, Xiao-Jun Tang, Ying-Xiong Jin, Ting Lei

Sheng Li Xue Bao· February 2007

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[Effects of beta-cypermethrin on voltage-gated potassium channels in rat hippocampal CA3 neurons].
Zhi-Yan Fu, Chun-Yun DU, Yang Yao, Chao-Wei Liu, Yu-Tao Tian

Sheng Li Xue Bao· February 2007

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