Publications by authors named "Hamish D Toop"

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PAC-FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures.
Lyndsey L Anderson, Kristopher M Kahlig, Melissa L Barker-Haliski, Lillian G Matthews, Hamish D Toop

Epilepsia· August 2025

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Use of modulators and light to control crystallisation of a hydrogen bonded framework.
Phonlakrit Muang-Non, Hamish D Toop, Christian J Doonan, Nicholas G White

Chem Commun (Camb)· December 2021

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Insights into the Interaction between Immobilized Biocatalysts and Metal-Organic Frameworks: A Case Study of PCN-333.
Wenjie Yang, Weibin Liang, Luke A O'Dell, Hamish D Toop, Natasha Maddigan

JACS Au· December 2021

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Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia.
Matthew D Dun, Abdul Mannan, Callum J Rigby, Stephen Butler, Hamish D Toop

Leukemia· December 2020

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TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.
Adam M Collison, Junyao Li, Ana Pereira de Siqueira, Xuejiao Lv, Hamish D Toop

BMC Pulm Med· February 2019

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SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
Konstantinos Tzelepis, Etienne De Braekeleer, Demetrios Aspris, Isaia Barbieri, M S Vijayabaskar, Hamish D Toop

Nat Commun· December 2018

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A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism.
Nigel Turner, Xin Ying Lim, Hamish D Toop, Brenna Osborne, Amanda E Brandon

Nat Commun· August 2018

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Concise Total Synthesis of Dioncophylline E through an ortho-Arylation Strategy.
Hamish D Toop, Jason S Brusnahan, Jonathan C Morris

Angew Chem Int Ed Engl· July 2017

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Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.
Jennifer Batson, Hamish D Toop, Clara Redondo, Roya Babaei-Jadidi, Apirat Chaikuad

ACS Chem Biol· March 2017

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Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia.
Hamish D Toop, Matthew D Dun, Bryony K Ross, Hayley M Flanagan, Nicole M Verrills

Org Biomol Chem· May 2016

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Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors.
Hamish D Toop, Anthony S Don, Jonathan C Morris

Org Biomol Chem· December 2015

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MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity.
Jing Jing Li, Hock L Tay, Steven Maltby, Yang Xiang, Fiona Eyers, Hamish D Toop

J Allergy Clin Immunol· August 2015

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Tumor necrosis factor-related apoptosis-inducing ligand regulates hallmark features of airways remodeling in allergic airways disease.
Adam Collison, Junyao Li, Ana Pereira de Siqueira, Jie Zhang, Hamish D Toop

Am J Respir Cell Mol Biol· July 2014

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Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A.
Luke Hatchwell, Jason Girkin, Matthew D Dun, Matthew Morten, Nicole Verrills, Hamish D Toop

J Allergy Clin Immunol· June 2014

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A fluorescent assay for ceramide synthase activity.
Hyun Joon Kim, Qiao Qiao, Hamish D Toop, Jonathan C Morris, Anthony S Don

J Lipid Res· August 2012

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