Publications by authors named "Claire Fergus"

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Behavioral improvement in dystrophic mouse following repeated antisense oligonucleotides injections.
Artadokht Aghaeipour, Manuela Mitsogiannis, Claire Fergus, Konstantina Tetorou, Talia Gileadi

Mol Ther Nucleic Acids· December 2025

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The oncogene SLC35F2 is a high-specificity transporter for the micronutrients queuine and queuosine.
Lyubomyr Burtnyak, Yifeng Yuan, Erwina Stojek, Xiaobei Pan, Lankani Gunaratne, Claire Fergus

Proc Natl Acad Sci U S A· June 2025

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Impact of distinct dystrophin gene mutations on behavioral phenotypes of Duchenne muscular dystrophy.
Amel Saoudi, Manuela D Mitsogiannis, Faouzi Zarrouki, Claire Fergus, Erwina Stojek

Dis Model Mech· December 2024

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Networking to Optimize exon 53 Skipping in the Brain of Mouse Model.
Mathilde Doisy, Ophélie Vacca, Claire Fergus, Talia Gileadi, Minou Verhaeg

Biomedicines· December 2023

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Queuine Analogues Incorporating the 7-Aminomethyl-7-deazaguanine Core: Structure-Activity Relationships in the Treatment of Experimental Autoimmune Encephalomyelitis.
Michelle Cotter, Sreeja Varghese, Franciane Chevot, Claire Fergus, Vincent P Kelly

ChemMedChem· September 2023

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Investigating the Impact of Delivery Routes for Exon Skipping Therapies in the CNS of DMD Mouse Models.
Amel Saoudi, Claire Fergus, Talia Gileadi, Federica Montanaro, Jennifer E Morgan

Cells· March 2023

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CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages.
Ciara G Doran, Ryoichi Sugisawa, Michael Carty, Fiona Roche, Claire Fergus

J Biol Chem· December 2021

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The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity.
Claire Fergus, Mashael Al-Qasem, Michelle Cotter, Ciara M McDonnell, Emiliano Sorrentino

Nucleic Acids Res· May 2021

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The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNA via a sequential bi-bi mechanism.
Mashael A Alqasem, Claire Fergus, J Mike Southern, Stephen J Connon, Vincent P Kelly

Chem Commun (Camb)· April 2020

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Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells.
Patti Hayes, Claire Fergus, Magda Ghanim, Cansu Cirzi, Lyubomyr Burtnyak

Nutrients· March 2020

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In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis.
Sreeja Varghese, Michelle Cotter, Franciane Chevot, Claire Fergus, Colm Cunningham

Nucleic Acids Res· February 2017

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The queuine micronutrient: charting a course from microbe to man.
Claire Fergus, Dominic Barnes, Mashael A Alqasem, Vincent P Kelly

Nutrients· April 2015

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