Publications by authors named "Claire Mackenzie"

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SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells.
Ryan Wallis, Bethany K Hughes, Madeleine Moore, Emily A O'Sullivan, Luke C McIlvenna, Claire Mackenzie

Aging (Albany NY)· October 2025

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Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments.
Stuart Lang, Daniel A Fletcher, Alain-Pierre Petit, Nicola Luise, Paul Fyfe, Claire J Mackenzie

ChemMedChem· July 2024

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Design and Synthesis of Covalent Inhibitors of FabA.
James S Martin, Claire J Mackenzie, De Lin, Nadine Homeyer, David W Gray

ACS Omega· April 2023

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Determination of orally administered 1,8-Cineol in nasal polyp tissues from chronic rhinosinusitis patients using gas chromatography: mass spectrometry.
Claire MacKenzie, Thomas Goerke, Mark Buecking, Mathias Heidemann, Anke Leichtle

Sci Rep· March 2023

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Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.
Caroline Wilson, Peter Ray, Fabio Zuccotto, Jorge Hernandez, Anup Aggarwal, Claire Mackenzie

J Med Chem· January 2022

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Synthesis of a Series of Diaminoindoles.
James S Martin, Claire J Mackenzie, Ian H Gilbert

J Org Chem· September 2021

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Identification of 6-amino-1-pyrazolo[3,4-]pyrimidines with efficacy against visceral leishmaniasis.
Michael G Thomas, Manu De Rycker, Myriam Ajakane, Sabrinia D Crouch, Lorna Campbell, Claire J Mackenzie

RSC Med Chem· October 2020

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Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase.
Leah S Torrie, David A Robinson, Michael G Thomas, Judith V Hobrath, Sharon M Shepherd, Claire J Mackenzie

ACS Infect Dis· May 2020

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Characterising covalent warhead reactivity.
James S Martin, Claire J MacKenzie, Daniel Fletcher, Ian H Gilbert

Bioorg Med Chem· May 2019

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Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.
Michael G Thomas, Manu De Rycker, Myriam Ajakane, Sébastian Albrecht, Ana Isabel Álvarez-Pedraglio, Claire J MacKenzie

J Med Chem· February 2019

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Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA.
Federica Prati, Fabio Zuccotto, Daniel Fletcher, Maire A Convery, Raquel Fernandez-Menendez, Claire Mackenzie

ChemMedChem· April 2018

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Correction for Arora et al., "Respiratory Flexibility in Response to Inhibition of Cytochrome Oxidase in ".
Kriti Arora, Bernardo Ochoa-Montaño, Patricia S Tsang, Tom L Blundell, Stephanie S Dawes, Claire J Mackenzie

Antimicrob Agents Chemother· September 2017

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Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.
Yumi Park, Angela Pacitto, Tracy Bayliss, Laura A T Cleghorn, Zhe Wang, Claire J MacKenzie

ACS Infect Dis· January 2017

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Evidence-Based Management of Postural Control in a Child with Cerebral Palsy.
Claire MacKenzie, Susan McIlwain

Physiother Can· August 2015

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Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.
Kriti Arora, Bernardo Ochoa-Montaño, Patricia S Tsang, Tom L Blundell, Stephanie S Dawes, Claire J Mackenzie

Antimicrob Agents Chemother· November 2014

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Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
Juan Carlos Pizarro, Tanya Hills, Guillermo Senisterra, Amy K Wernimont, Claire Mackenzie

PLoS Negl Trop Dis· May 2014

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