Publications by authors named "Clint Mitchell"

Claim this Profile
U
Use of Remote Regulatory Assessment (RRA) for Site Evaluations during the COVID-19 Pandemic: The USFDA's Office of Study Integrity and Surveillance (OSIS) Perspective.
Tahseen Mirza, Nicola Fenty-Stewart, Clint Mitchell, Brian Folian, Sean Kassim

AAPS PharmSciTech· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
Guo Zhang, Margaret A Park, Clint Mitchell, Teneille Walker, Hossein Hamed

J Biol Chem· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95.
Anindita Das, David Durrant, Clint Mitchell, Paul Dent, Surinder K Batra

Oncotarget· January 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death.
Clint Mitchell, Hossein A Hamed, Nichola Cruickshanks, Yong Tang, M Danielle Bareford

Cancer Biol Ther· August 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
Margaret A Park, Hossein A Hamed, Clint Mitchell, Nichola Cruickshanks, Rupesh Dash

Mol Pharmacol· March 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells.
Clint Mitchell, Margaret Park, Patrick Eulitt, Chen Yang, Adly Yacoub

Mol Pharmacol· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo.
Clint Mitchell, Adly Yacoub, Hamed Hossein, Aditi Pandya Martin, M Danielle Bareford

Cancer Biol Ther· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.
Anindita Das, David Durrant, Clint Mitchell, Eric Mayton, Nicholas N Hoke

Proc Natl Acad Sci U S A· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway.
Margaret A Park, Clint Mitchell, Guo Zhang, Adly Yacoub, Jeremy Allegood

Cancer Res· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of oxidative stress and MAPK signaling in reference moist smokeless tobacco-induced HOK-16B cell death.
Clint Mitchell, Andrew R Joyce, John T Piper, Robert J McKallip, Marc W Fariss

Toxicol Lett· May 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
1
17-allylamino-17-demethoxygeldanamycin and MEK1/2 inhibitors kill GI tumor cells via Ca2+-dependent suppression of GRP78/BiP and induction of ceramide and reactive oxygen species.
Teneille Walker, Clint Mitchell, Margaret A Park, Adly Yacoub, Mohamed Rahmani

Mol Cancer Ther· May 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.
Adly Yacoub, Hossein A Hamed, Jeremy Allegood, Clint Mitchell, Sarah Spiegel

Cancer Res· February 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy.
Aditi Pandya Martin, Clint Mitchell, Mohamed Rahmani, Kenneth P Nephew, Steven Grant

Cancer Biol Ther· November 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts.
Dmitri Kapitonov, Jeremy C Allegood, Clint Mitchell, Nitai C Hait, Jorge A Almenara

Cancer Res· September 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
Teneille Walker, Clint Mitchell, Margaret A Park, Adly Yacoub, Martin Graf

Mol Pharmacol· August 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing.
Aditi Pandya Martin, Margaret A Park, Clint Mitchell, Teneille Walker, Mohamed Rahmani

Mol Pharmacol· August 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Autophagy and the functional roles of Atg5 and beclin-1 in the anti-tumor effects of 3beta androstene 17alpha diol neuro-steroid on malignant glioma cells.
Martin R Graf, Wentao Jia, Ross S Johnson, Paul Dent, Clint Mitchell

J Steroid Biochem Mol Biol· July 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance.
Nathan T Ihle, Robert Lemos, Peter Wipf, Adly Yacoub, Clint Mitchell

Cancer Res· January 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.
Margaret A Park, Guo Zhang, Aditi Pandya Martin, Hossein Hamed, Clint Mitchell

Cancer Biol Ther· October 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation.
Aditi Pandya Martin, Anna Miller, Luni Emad, Mohammed Rahmani, Teneille Walker, Clint Mitchell

Mol Pharmacol· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
Guo Zhang, Margaret A Park, Clint Mitchell, Teneille Walker, Hossein Hamed

J Biol Chem· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
Guo Zhang, Margaret A Park, Clint Mitchell, Hossein Hamed, Mohamed Rahmani

Clin Cancer Res· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
Margaret A Park, Guo Zhang, Clint Mitchell, Mohamed Rahmani, Hossein Hamed

Mol Cancer Ther· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo.
Hossein Hamed, Clint Mitchell, Margaret A Park, David Hanna, Aditi Pandya Martin

Cancer Biol Ther· April 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transient exposure of carcinoma cells to RAS/MEK inhibitors and UCN-01 causes cell death in vitro and in vivo.
Hossein Hamed, William Hawkins, Clint Mitchell, Donna Gilfor, Guo Zhang

Mol Cancer Ther· March 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis