Publications by authors named "Colin J B Harvey"

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Resistance Gene-Guided Genome Mining Reveals RPL10 as the Target of Ligustrone A.
Danielle A Yee, Ross D Overacker, Michelle F Grau, Amber Cornelius, Adrianne Pigula, Colin J B Harvey

J Am Chem Soc· June 2025

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Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.
Thu P Nguyen, Min Fang, Jiwoong Kim, Baiyun Wang, Elisa Lin, Colin J B Harvey

Cell Chem Biol· November 2023

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Resistance gene-guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases.
Kyle L Dunbar, Bruno Perlatti, Nicholas Liu, Amber Cornelius, Daniel Mummau, Colin J B Harvey

Proc Natl Acad Sci U S A· November 2023

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Turning the world's DNA into new medicines.
J J David Ho, Kyle L Dunbar, Brian Naughton, Colin J B Harvey

Trends Biotechnol· June 2022

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Anti-cryptococcal activity of preussolides A and B, phosphoethanolamine-substituted 24-membered macrolides, and leptosin C from coprophilous isolates of Preussia typharum.
Bruno Perlatti, Nan Lan, Meichun Xiang, Cody E Earp, Joseph E Spraker, Colin J B Harvey

J Ind Microbiol Biotechnol· December 2021

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Targeted Genome Mining Reveals the Biosynthetic Gene Clusters of Natural Product CYP51 Inhibitors.
Nicholas Liu, Elizabeth D Abramyan, Wei Cheng, Bruno Perlatti, Colin J B Harvey

J Am Chem Soc· April 2021

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Identification of the Antifungal Metabolite Chaetoglobosin P From Using a Inhibition Assay: Insights Into Mode of Action and Biosynthesis.
Bruno Perlatti, Connie B Nichols, Nan Lan, Philipp Wiemann, Colin J B Harvey

Front Microbiol· July 2020

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Acrophiarin (antibiotic S31794/F-1) from Penicillium arenicola shares biosynthetic features with both Aspergillus- and Leotiomycete-type echinocandins.
Nan Lan, Bruno Perlatti, Daniel J Kvitek, Philipp Wiemann, Colin J B Harvey

Environ Microbiol· June 2020

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A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.
Jian Li, Kristen Kolberg, Ulrich Schlecht, Robert P St Onge, Ana Maria Aparicio, Colin J B Harvey

J Biol Chem· January 2019

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HEx: A heterologous expression platform for the discovery of fungal natural products.
Colin J B Harvey, Mancheng Tang, Ulrich Schlecht, Joe Horecka, Curt R Fischer

Sci Adv· April 2018

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Reversible Product Release and Recapture by a Fungal Polyketide Synthase Using a Carnitine Acyltransferase Domain.
Leibniz Hang, Man-Cheng Tang, Colin J B Harvey, Claire G Page, Jian Li

Angew Chem Int Ed Engl· August 2017

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Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.
Yong Fuga Li, Kathleen J S Tsai, Colin J B Harvey, James Jian Li, Beatrice E Ary

Fungal Genet Biol· April 2016

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Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket.
Colin J B Harvey, Joseph D Puglisi, Vijay S Pande, David E Cane, Chaitan Khosla

J Am Chem Soc· July 2012

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Improved precursor-directed biosynthesis in E. coli via directed evolution.
Ho Young Lee, Colin J B Harvey, David E Cane, Chaitan Khosla

J Antibiot (Tokyo)· January 2011

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