Publications by authors named "Colin J Loweth"

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Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3.
Val S Goodfellow, Colin J Loweth, Satheesh B Ravula, Torsten Wiemann, Thong Nguyen

J Med Chem· October 2013

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The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders.
Daniel F Marker, Marie-Ève Tremblay, Jenna M Puccini, Justin Barbieri, Mary A Gantz Marker, Colin J Loweth

J Neurosci· June 2013

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Selection, synthesis, and structure-activity relationship of tetrahydropyrido[4,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists.
Marion C Lanier, Miklos Feher, Neil J Ashweek, Colin J Loweth, Jaimie K Rueter

Bioorg Med Chem· August 2007

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Identification of 2-(4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-3-yl)-ethylamine derivatives as novel GnRH receptor antagonists.
Mi Chen, Zhiqiang Guo, Marion C Lanier, Liren Zhao, Stephen F Betz, Colin J Loweth

Bioorg Med Chem Lett· July 2007

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Allosteric and orthosteric binding modes of two nonpeptide human gonadotropin-releasing hormone receptor antagonists.
Susan K Sullivan, Michael S Brown, Yinghong Gao, Colin J Loweth, Francisco M Lio

Biochemistry· December 2006

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Genomic effects of polyamide/DNA interactions on mRNA expression.
Lubica Supekova, John Paul Pezacki, Andrew I Su, Colin J Loweth, Rainer Riedl

Chem Biol· July 2002

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DNA-Based Assembly of Gold Nanocrystals.
Colin J Loweth, W Brett Caldwell, Xiaogang Peng, A Paul Alivisatos, Peter G Schultz

Angew Chem Int Ed Engl· June 1999

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