Publications by authors named "Colin James"

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Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer.
Eileen E Parkes, Kienan I Savage, Tong Lioe, Clinton Boyd, Sophia Halliday, Jaqueline A James, Colin R James

Br J Cancer· February 2022

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Towards trauma-informed legal practice: a review.
Colin James

Psychiatr Psychol Law· February 2020

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Rabies in the Caribbean: A Situational Analysis and Historic Review.
Janine F R Seetahal, Alexandra Vokaty, Marco A N Vigilato, Christine V F Carrington, Jennifer Pradel, Colin James

Trop Med Infect Dis· August 2018

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Evaluation of the taste-masking effects of (2-hydroxypropyl)-β-cyclodextrin on ranitidine hydrochloride; a combined biosensor, spectroscopic and molecular modelling assessment.
Sai Kin Chay, Alison V Keating, Colin James, Abil E Aliev, Shozeb Haider

RSC Adv· January 2018

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The culture of pretence: a hidden barrier to recognising, disclosing and ending domestic violence.
Lyn Francis, Deborah Loxton, Colin James

J Clin Nurs· August 2017

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Thromboxane A2 receptor (TBXA2R) is a potent survival factor for triple negative breast cancers (TNBCs).
Katy Orr, Niamh E Buckley, Paula Haddock, Colin James, Jean-Luc Parent

Oncotarget· August 2016

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Synthesis, anti-mycobacterial activity and DNA sequence-selectivity of a library of biaryl-motifs containing polyamides.
Federico Brucoli, Juan D Guzman, Arundhati Maitra, Colin H James, Keith R Fox

Bioorg Med Chem· July 2015

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Effect of hairpin loop structure on reactivity, sequence preference and adduct orientation of a DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour agent.
David E Thurston, Higia Vassoler, Paul J M Jackson, Colin H James, Khondaker M Rahman

Org Biomol Chem· April 2015

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Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition.
Paul J M Jackson, Colin H James, Terence C Jenkins, Khondaker M Rahman, David E Thurston

ACS Chem Biol· October 2014

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Identification and validation of an anthracycline/cyclophosphamide-based chemotherapy response assay in breast cancer.
Jude M Mulligan, Laura A Hill, Steve Deharo, Gareth Irwin, David Boyle, Colin R James, Jacqueline James

J Natl Cancer Inst· January 2014

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Determining the community prevalence of acute gastrointestinal illness and gaps in surveillance of acute gastroenteritis and foodborne diseases in Guyana.
Shamdeo Persuad, Pheona Mohamed-Rambaran, Alexis Wilson, Colin James, Lisa Indar

J Health Popul Nutr· December 2013

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An extended pyrrolobenzodiazepine-polyamide conjugate with selectivity for a DNA sequence containing the ICB2 transcription factor binding site.
Federico Brucoli, Rachel M Hawkins, Colin H James, Paul J M Jackson, Geoff Wells

J Med Chem· August 2013

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GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models.
Khondaker M Rahman, Paul J M Jackson, Colin H James, B Piku Basu, John A Hartley

J Med Chem· April 2013

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Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates.
Khondaker M Rahman, Helena Rosado, Joao B Moreira, Eva-Anne Feuerbaum, Keith R Fox, Colin H James

J Antimicrob Chemother· July 2012

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Observation of a single-stranded DNA/pyrrolobenzodiazepine adduct.
Khondaker M Rahman, Colin H James, Tam T T Bui, Alex F Drake, David E Thurston

J Am Chem Soc· December 2011

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Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers.
Khondaker M Rahman, Colin H James, David E Thurston

Nucleic Acids Res· July 2011

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Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box.
Federico Brucoli, Rachel M Hawkins, Colin H James, Geoff Wells, Terence C Jenkins

Bioorg Med Chem Lett· June 2011

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Human epidermal growth factor receptor 2-positive breast cancer relapsing post-adjuvant trastuzumab: pattern of recurrence, treatment and outcome.
Jonathan Krell, Colin R James, Deep Shah, Ondrej Gojis, Adrian Lim

Clin Breast Cancer· June 2011

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Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy.
Khondaker M Rahman, Colin H James, David E Thurston

Org Biomol Chem· March 2011

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DNA Sequence Preference and Adduct Orientation of Pyrrolo[2,1-c][1,4]benzodiazepine Antitumor Agents.
Khondaker M Rahman, Higia Vassoler, Colin H James, David E Thurston

ACS Med Chem Lett· November 2010

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Rechallenging with anthracyclines and taxanes in metastatic breast cancer.
Carlo Palmieri, Jonathan Krell, Colin R James, Catherine Harper-Wynne, Vivek Misra

Nat Rev Clin Oncol· October 2010

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BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer.
Julia J Gorski, Colin R James, Jennifer E Quinn, Gail E Stewart, Kieran Crosbie Staunton

Breast Cancer Res Treat· August 2010

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Structure-activity relationships of monomeric C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor agents.
Dyeison Antonow, Maciej Kaliszczak, Gyoung-Dong Kang, Marissa Coffils, Arnaud C Tiberghien, Colin H James

J Med Chem· April 2010

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Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells.
Gemma Bellett, Jane M Carter, Jennifer Keynton, Deborah Goldspink, Colin James

Cell Motil Cytoskeleton· October 2009

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The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links.
Khondaker M Rahman, Andrew S Thompson, Colin H James, Mathangi Narayanaswamy, David E Thurston

J Am Chem Soc· September 2009

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