Publications by authors named "Colin M House"

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SFRP4 drives invasion in gastric cancer and is an early predictor of recurrence.
Rita A Busuttil, Joshy George, Colin M House, Stephen Lade, Catherine Mitchell

Gastric Cancer· May 2021

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Differential cleavage of viral polypeptides by allotypic variants of granzyme B skews immunity to mouse cytomegalovirus.
Vivien R Sutton, Christopher Andoniou, Michael G Leeming, Colin M House, Sally V Watt

Biochim Biophys Acta Proteins Proteom· September 2020

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Pits and CtBP Control Tissue Growth in with the Hippo Pathway Transcription Repressor Tgi.
Joseph H A Vissers, Lucas G Dent, Colin M House, Shu Kondo, Kieran F Harvey

Genetics· May 2020

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Regulation of perforin activation and pre-synaptic toxicity through C-terminal glycosylation.
Imran G House, Colin M House, Amelia J Brennan, Omer Gilan, Mark A Dawson

EMBO Rep· October 2017

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Real-time visualization of perforin nanopore assembly.
Carl Leung, Adrian W Hodel, Amelia J Brennan, Natalya Lukoyanova, Sharon Tran, Colin M House

Nat Nanotechnol· May 2017

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Inhibiting the system x/glutathione axis selectively targets cancers with mutant-p53 accumulation.
David S Liu, Cuong P Duong, Sue Haupt, Karen G Montgomery, Colin M House

Nat Commun· March 2017

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Foxp3 expression in macrophages associated with RENCA tumors in mice.
Christel Devaud, Carmen S M Yong, Liza B John, Jennifer A Westwood, Connie P M Duong, Colin M House

PLoS One· November 2015

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Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Geoffrey M Matthews, Parinaz Mehdipour, Leonie A Cluse, Katrina J Falkenberg, Eric Wang, Colin M House

Blood· November 2015

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The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.
Anna Chen, Christina S F Wong, Mira C P Liu, Colin M House, Jaclyn Sceneay

Oncotarget· January 2015

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Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy.
Christina S F Wong, Jaclyn Sceneay, Colin M House, Heloise M Halse, Mira C P Liu

Cancer Res· April 2012

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Relative Expression Levels Rather Than Specific Activity Plays the Major Role in Determining In Vivo AKT Isoform Substrate Specificity.
Rachel S Lee, Colin M House, Briony E Cristiano, Ross D Hannan, Richard B Pearson

Enzyme Res· November 2011

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A phospho-proteomic screen identifies novel S6K1 and mTORC1 substrates revealing additional complexity in the signaling network regulating cell growth.
Katarzyna Jastrzebski, Katherine M Hannan, Colin M House, Sandy S-C Hung, Richard B Pearson

Cell Signal· August 2011

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IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.
Michael S Anglesio, Joshy George, Hagen Kulbe, Michael Friedlander, Danny Rischin, Colin M House

Clin Cancer Res· April 2011

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Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
Åslaug Helland, Michael S Anglesio, Joshy George, Prue A Cowin, Cameron N Johnstone, Colin M House

PLoS One· April 2011

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Siah proteins: novel drug targets in the Ras and hypoxia pathways.
Colin M House, Andreas Möller, David D L Bowtell

Cancer Res· December 2009

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Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function.
Ilia Voskoboinik, Vivien R Sutton, Annette Ciccone, Colin M House, Jenny Chia

Blood· August 2007

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Elucidation of the substrate binding site of Siah ubiquitin ligase.
Colin M House, Nancy C Hancock, Andreas Möller, Brett A Cromer, Victor Fedorov

Structure· April 2006

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A binding motif for Siah ubiquitin ligase.
Colin M House, Ian J Frew, Huei-Luen Huang, Gerhard Wiche, Nadia Traficante

Proc Natl Acad Sci U S A· March 2003

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The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice.
Ross A Dickins, Ian J Frew, Colin M House, Moira K O'Bryan, Andrew J Holloway

Mol Cell Biol· April 2002

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Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.
Galina Polekhina, Colin M House, Nadia Traficante, Joel P Mackay, Frédéric Relaix

Nat Struct Biol· January 2002

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