Publications by authors named "Colin Phipps"

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Quantitative Measurement of Rate of Targeted Protein Degradation.
Thomas L Lynch, Violeta L Marin, Ryan A McClure, Colin Phipps, Judith A Ronau

ACS Chem Biol· July 2024

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Assumptions Underlying Hepatic Clearance Models: Recognizing the Influence of Saturable Protein Binding on Driving Force Concentration and Discrimination Between Models of Hepatic Clearance.
Julia A Schulz Pauly, Jin Wang, Colin J Phipps, John Cory Kalvass

Drug Metab Dispos· August 2023

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Industry Perspective on the Pharmacokinetic and Absorption, Distribution, Metabolism, and Excretion Characterization of Heterobifunctional Protein Degraders.
Laurie P Volak, Heide Marika Duevel, Sara Humphreys, David Nettleton, Colin Phipps

Drug Metab Dispos· July 2023

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PBPK model for antibody disposition in mouse brain: validation using large-pore microdialysis data.
Shengjia Wu, Florie Le Prieult, Colin J Phipps, Mario Mezler, Dhaval K Shah

J Pharmacokinet Pharmacodyn· December 2022

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High-dose methotrexate is effective for prevention of isolated CNS relapse in diffuse large B cell lymphoma.
Shin Yeu Ong, Sanjay de Mel, Nicholas Francis Grigoropoulos, Yunxin Chen, Yan Chin Tan, Colin Phipps

Blood Cancer J· August 2021

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No association between germline mutations and hemophagocytic lymphohistiocytosis in natural killer/T-cell lymphoma.
Shin Yeu Ong, Jing Quan Lim, Nicholas Grigoropoulos, Yurike Laurensia, Dachuan Huang, Colin Phipps

Haematologica· June 2021

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Harnessing cerebrospinal fluid circulation for drug delivery to brain tissues.
Ghazal Naseri Kouzehgarani, Thomas Feldsien, Herbert H Engelhard, Kuldip K Mirakhur, Colin Phipps

Adv Drug Deliv Rev· June 2021

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Correction to: Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma.
Jing Quan Lim, Dachuan Huang, Tiffany Tang, Daryl Tan, Yurike Laurensia, Colin Phipps

Leukemia· April 2021

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Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma.
Jing Quan Lim, Dachuan Huang, Tiffany Tang, Daryl Tan, Yurike Laurensia, Colin Phipps

Leukemia· December 2020

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Antibody-drug conjugates as targeted therapies: Are we there yet? A critical review of the current clinical landscape.
Edit Tarcsa, Magali R Guffroy, Hadi Falahatpisheh, Colin Phipps, John C Kalvass

Drug Discov Today Technol· December 2020

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Cell-of-origin and bone marrow involvement increase specificity of defining patients with diffuse large B-cell lymphoma at high risk of CNS relapse: a study of 793 patients treated with chemoimmunotherapy in Asia.
Shin Yeu Ong, Colin Phipps, Chandramouli Nagarajan, Tiffany Tang, Soon Thye Lim

Leuk Lymphoma· January 2020

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Pralatrexate Induces Long-Term Remission in Relapsed Subcutaneous Panniculitis-Like T-Cell Lymphoma.
Shin Yeu Ong, Colin Phipps, Hartirathpal Kaur, Leonard Tan, Yuh Shan Lee

Ann Acad Med Singap· September 2019

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The impact of time from diagnosis to treatment in diffuse large B-cell lymphoma.
Colin Phipps, Yuh Shan Lee, Hao Ying, Chandramouli Nagarajan, Nicholas Grigoropoulos

Leuk Lymphoma· October 2018

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Allogeneic haematopoietic cell transplantation for extranodal natural killer/T-cell lymphoma, nasal type: a CIBMTR analysis.
Abraham S Kanate, Alyssa DiGilio, Kwang W Ahn, Monzr Al Malki, Eric Jacobsen, Colin D Phipps

Br J Haematol· September 2018

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Mechanistic Modeling of Antibody-Drug Conjugate Internalization at the Cellular Level Reveals Inefficient Processing Steps.
Kenneth R Durbin, Colin Phipps, Xiaoli Liao

Mol Cancer Ther· June 2018

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Mathematical and Experimental Validation of Flux Dialysis Method: An Improved Approach to Measure Unbound Fraction for Compounds with High Protein Binding and Other Challenging Properties.
J Cory Kalvass, Colin Phipps, Gary J Jenkins, Patricia Stuart, Xiaomei Zhang

Drug Metab Dispos· April 2018

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Pharmacokinetic Considerations for Antibody-Drug Conjugates against Cancer.
Paul Malik, Colin Phipps, Andrea Edginton, Jonathan Blay

Pharm Res· December 2017

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Outcomes of patients with peripheral T-cell lymphoma in first complete remission: data from three tertiary Asian cancer centers.
Tiffany Tang, Lay Poh Khoo, Cindy Lim, Jun Soo Ham, Seok Jin Kim, Colin Phipps

Blood Cancer J· December 2017

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Quantifying the effects of antiangiogenic and chemotherapy drug combinations on drug delivery and treatment efficacy.
Sirin Yonucu, Defne Yιlmaz, Colin Phipps, Mehmet Burcin Unlu, Mohammad Kohandel

PLoS Comput Biol· September 2017

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Population PBPK modelling of trastuzumab: a framework for quantifying and predicting inter-individual variability.
Paul R V Malik, Abdullah Hamadeh, Colin Phipps, Andrea N Edginton

J Pharmacokinet Pharmacodyn· June 2017

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PD1 blockade with pembrolizumab is highly effective in relapsed or refractory NK/T-cell lymphoma failing l-asparaginase.
Yok-Lam Kwong, Thomas S Y Chan, Daryl Tan, Seok Jin Kim, Li-Mei Poon, Colin Phipps

Blood· April 2017

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Clinicopathological features and outcome of chronic lymphocytic leukaemia in Chinese patients.
Thomas Sau-Yan Chan, Yuh-Shan Lee, Ilaria Del Giudice, Marilisa Marinelli, Caterina Ilari, Colin Phipps

Oncotarget· April 2017

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Thirty Years of Bone Marrow Transplantation in the Singapore General Hospital.
Colin Phipps, Aloysius Yl Ho, Yeh Ching Linn, Sathish Gopalakrishnan, Ai Leen Ang

Ann Acad Med Singap· July 2016

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Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects.
Hamid R Molavian, Aaron Goldman, Colin J Phipps, Mohammad Kohandel, Bradly G Wouters

Sci Rep· June 2016

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What We Learned From Plasma BK-Virus Monitoring in Allogeneic Hematopoietic Transplant Recipients.
Aditi Ghosh, Thuan Tong Tan, Yeh Ching Linn, Sathish Gopalakrishnan, Yeow Tee Goh, Colin Phipps

Transplantation· April 2016

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