Publications by authors named "David Nettleton"

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Tight-Binding Small-Molecule Carboxylesterase 2 Inhibitors Reduce Intracellular Irinotecan Activation.
Karishma Kailass, Dominick Casalena, Lina Jenane, Gregor McEdwards, Douglas S Auld, David Nettleton

J Med Chem· February 2024

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Smart Sensor Control and Monitoring of an Automated Cell Expansion Process.
David F Nettleton, Núria Marí-Buyé, Helena Marti-Soler, Joseph R Egan, Simon Hort

Sensors (Basel)· December 2023

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Elaborating the potential of Artificial Intelligence in automated CAR-T cell manufacturing.
Niklas Bäckel, Simon Hort, Tamás Kis, David F Nettleton, Joseph R Egan

Front Mol Med· September 2023

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Industry Perspective on the Pharmacokinetic and Absorption, Distribution, Metabolism, and Excretion Characterization of Heterobifunctional Protein Degraders.
Laurie P Volak, Heide Marika Duevel, Sara Humphreys, David Nettleton, Colin Phipps

Drug Metab Dispos· July 2023

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Energy Consumption Optimization of a Fluid Bed Dryer in Pharmaceutical Manufacturing Using EDA (Exploratory Data Analysis).
Roberto Barriga, Miquel Romero, Houcine Hassan, David F Nettleton

Sensors (Basel)· April 2023

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Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands.
Jeffrey T Bagdanoff, Thomas M Smith, Martin Allan, Peter O'Donnell, Zachary Nguyen, David O Nettleton

Cell Chem Biol· January 2023

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Identification of a PCSK9-LDLR disruptor peptide with in vivo function.
Margaret E Brousseau, Kevin B Clairmont, Glen Spraggon, Alec N Flyer, Andrei A Golosov, David Nettleton

Cell Chem Biol· February 2022

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Scalable Biosynthetic Production of Knotted Peptides Enables ADME and Thermodynamic Folding Studies.
Christopher J Schwalen, Charles Babu, Swastik Phulera, Qin Hao, Daniel Wall, David O Nettleton

ACS Omega· November 2021

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Review on the photonic techniques suitable for automatic monitoring of the composition of multi-materials wastes in view of their posterior recycling.
Cuauhtémoc Araujo-Andrade, Elodie Bugnicourt, Laurent Philippet, Laura Rodriguez-Turienzo, David Nettleton

Waste Manag Res· May 2021

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Design of Thioether Cyclic Peptide Scaffolds with Passive Permeability and Oral Exposure.
Andrei A Golosov, Alec N Flyer, Jakal Amin, Charles Babu, Christian Gampe, David Nettleton

J Med Chem· March 2021

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Bio-Based Packaging: Materials, Modifications, Industrial Applications and Sustainability.
Corina L Reichert, Elodie Bugnicourt, Maria-Beatrice Coltelli, Patrizia Cinelli, Andrea Lazzeri, David F Nettleton

Polymers (Basel)· July 2020

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Predicting rice blast disease: machine learning versus process-based models.
David F Nettleton, Dimitrios Katsantonis, Argyris Kalaitzidis, Natasa Sarafijanovic-Djukic, Pau Puigdollers

BMC Bioinformatics· October 2019

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Medicinal Chemistry Profiling of Monocyclic 1,2-Azaborines.
Peng Zhao, David O Nettleton, Rajeshri G Karki, Frédéric J Zécri, Shih-Yuan Liu

ChemMedChem· March 2017

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Assessment of cytochrome p450 enzyme inhibition and inactivation in drug discovery and development.
David O Nettleton, Heidi J Einolf

Curr Top Med Chem· July 2011

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Predicting safety toleration of pharmaceutical chemical leads: cytotoxicity correlations to exploratory toxicity studies.
John W Benbow, Jiri Aubrecht, Michael J Banker, David Nettleton, Michael D Aleo

Toxicol Lett· September 2010

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A combined model for predicting CYP3A4 clinical net drug-drug interaction based on CYP3A4 inhibition, inactivation, and induction determined in vitro.
Odette A Fahmi, Tristan S Maurer, Mary Kish, Edwin Cardenas, Sherri Boldt, David Nettleton

Drug Metab Dispos· August 2008

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Fluorescently labeled analogues of dofetilide as high-affinity fluorescence polarization ligands for the human ether-a-go-go-related gene (hERG) channel.
David H Singleton, Helen Boyd, Jill V Steidl-Nichols, Matt Deacon, Marcel J de Groot, David O Nettleton

J Med Chem· June 2007

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Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis.
Vladi V Heredia, Jim Thomson, David Nettleton, Shaoxian Sun

Biochemistry· June 2006

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A new chemical tool for exploring the role of the PDE4D isozyme in leukocyte function.
Robert J Chambers, Kristin Abrams, Tessa A Castleberry, John B Cheng, Douglas A Fisher, David O Nettleton

Bioorg Med Chem Lett· February 2006

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Simple strategies for reducing sample loads in in vitro metabolic stability high-throughput screening experiments: a comparison between traditional, two-time-point and pooled sample analyses.
Sabrina X Zhao, Darcy Forman, Nora Wallace, Bill J Smith, Daniel Meyer, David Nettleton

J Pharm Sci· January 2005

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