Publications by authors named "Colin R O'Dowd"

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USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.
Anamarija Jurisic, Pei-Ju Sung, Mark Wappett, Julien Daubriac, Ian T Lobb, Colin R O'Dowd

Clin Transl Med· April 2024

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Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.
Natalie Page, Mark Wappett, Colin R O'Dowd, Martin O'Rourke, Gerald Gavory

Sci Rep· September 2022

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Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.
Colin R O'Dowd, Matthew D Helm, J S Shane Rountree, Jakub T Flasz, Elias Arkoudis

ACS Med Chem Lett· March 2018

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Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.
Gerald Gavory, Colin R O'Dowd, Matthew D Helm, Jakub Flasz, Elias Arkoudis

Nat Chem Biol· February 2018

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Chemoenzymatic synthesis of carbasugars (+)-pericosines A-C from diverse aromatic cis-dihydrodiol precursors.
Derek R Boyd, Narain D Sharma, Carmen A Acaru, John F Malone, Colin R O'Dowd

Org Lett· May 2010

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Chemoenzymatic synthesis of the carbasugars carba-beta-L-galactopyranose, carba-beta-L-talopyranose and carba-alpha-L-talopyranose from methyl benzoate.
Derek R Boyd, Narain D Sharma, Nigel I Bowers, Gerard B Coen, John F Malone, Colin R O'Dowd

Org Biomol Chem· March 2010

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syn-Benzene dioxides: chemoenzymatic synthesis from 2,3-cis-dihydrodiol derivatives of monosubstituted benzenes and their application in the synthesis of regioisomeric 1,2- and 3,4-cis-dihydrodiols and 1,4-dioxocins.
Derek R Boyd, Narain D Sharma, Nuria M Llamas, Colin R O'Dowd, Christopher C R Allen

Org Biomol Chem· July 2007

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Chemoenzymatic synthesis of the trans-dihydrodiol isomers of monosubstituted benzenes via anti-benzene dioxides.
Derek R Boyd, Narain D Sharma, Nuria M Llamas, Colin R O'Dowd, Christopher C R Allen

Org Biomol Chem· June 2006

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cis-Dihydrodiol, arene oxide and phenol metabolites of dictamnine: key intermediates in the biodegradation and biosynthesis of furoquinoline alkaloids.
Derek R Boyd, Narain D Sharma, Colin R O'Dowd, Jonathan G Carroll, Pui L Loke

Chem Commun (Camb)· August 2005

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Chemoenzymatic synthesis of carbasugars from iodobenzene.
Derek R Boyd, Narain D Sharma, Nuria M Llamas, John F Malone, Colin R O'Dowd

Org Biomol Chem· May 2005

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