Publications by authors named "Colin T Mant"

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Design of Novel Amphipathic α-Helical Antimicrobial Peptides with No Toxicity as Therapeutics against the Antibiotic-Resistant Gram-Negative Bacterial Pathogen, .
Colin T Mant, Ziqing Jiang, Lajos Gera, Tim Davis, Robert S Hodges

J Med Chem Drug Des· May 2019

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De Novo Designed Amphipathic α-Helical Antimicrobial Peptides Incorporating Dab and Dap Residues on the Polar Face To Treat the Gram-Negative Pathogen, Acinetobacter baumannii.
Colin T Mant, Ziqing Jiang, Lajos Gera, Tim Davis, Kirsten L Nelson

J Med Chem· April 2019

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Separation of highly charged (+5 to +10) amphipathic α-helical peptide standards by cation-exchange and reversed-phase high-performance liquid chromatography.
Colin T Mant, Andrew Byars, Sean Ankarlo, Ziqing Jiang, Robert S Hodges

J Chromatogr A· November 2018

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Role of positively charged residues on the polar and non-polar faces of amphipathic α-helical antimicrobial peptides on specificity and selectivity for Gram-negative pathogens.
Ziqing Jiang, Colin T Mant, Michael Vasil, Robert S Hodges

Chem Biol Drug Des· January 2018

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Optimized purification of a fusion protein by reversed-phase high performance liquid chromatography informed by the linear solvent strength model.
Isaac B Falconer, Colin T Mant, C James McKnight, Liliya Vugmeyster, Robert Hodges

J Chromatogr A· October 2017

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Separation of Peptides on HALO 2-Micron Particles.
Colin T Mant, Robert S Hodges

Curr Protoc Protein Sci· August 2016

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Platform technology to generate broadly cross-reactive antibodies to α-helical epitopes in hemagglutinin proteins from influenza A viruses.
Ziqing Jiang, Lajos Gera, Colin T Mant, Brooke Hirsch, Zhe Yan

Biopolymers· March 2016

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Opposing activity changes in AMP deaminase and AMP-activated protein kinase in the hibernating ground squirrel.
Miguel A Lanaspa, L Elaine Epperson, Nanxing Li, Christina Cicerchi, Gabriela E Garcia, Colin T Mant

PLoS One· December 2015

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Structure-activity relationships of the antimicrobial peptide gramicidin S and its analogs: aqueous solubility, self-association, conformation, antimicrobial activity and interaction with model lipid membranes.
Thomas Abraham, Elmar J Prenner, Ruthven N A H Lewis, Colin T Mant, Sandro Keller

Biochim Biophys Acta· May 2014

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Structure-guided RP-HPLC chromatography of diastereomeric α-helical peptide analogs substituted with single amino acid stereoisomers.
Yibing Huang, Ling Pan, Lianjing Zhao, Colin T Mant, Robert S Hodges

Biomed Chromatogr· April 2014

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Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver.
Miguel A Lanaspa, Christina Cicerchi, Gabriela Garcia, Nanxing Li, Carlos A Roncal-Jimenez, Colin T Mant

PLoS One· May 2013

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An improved approach to hydrophilic interaction chromatography of peptides: salt gradients in the presence of high isocratic acetonitrile concentrations.
Colin T Mant, Ziqing Jiang, Barry E Boyes, Robert S Hodges

J Chromatogr A· February 2013

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Purification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriae.
Sheryl Zajdowicz, Jon C Haller, Amy E Krafft, Steve W Hunsucker, Colin T Mant

PLoS One· August 2012

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Design of peptide standards with the same composition and minimal sequence variation to monitor performance/selectivity of reversed-phase matrices.
Colin T Mant, Robert S Hodges

J Chromatogr A· March 2012

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Reversed-phase HPLC of peptides: Assessing column and solvent selectivity on standard, polar-embedded and polar endcapped columns.
Colin T Mant, Dziuleta Cepeniene, Robert S Hodges

J Sep Sci· October 2010

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Intrinsic amino acid side-chain hydrophilicity/hydrophobicity coefficients determined by reversed-phase high-performance liquid chromatography of model peptides: comparison with other hydrophilicity/hydrophobicity scales.
Colin T Mant, James M Kovacs, Hyun-Min Kim, David D Pollock, Robert S Hodges

Biopolymers· February 2010

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Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides.
Ziqing Jiang, Bart Jan Kullberg, Hein van der Lee, Adriana I Vasil, John D Hale, Colin T Mant

Chem Biol Drug Des· December 2008

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HPLC analysis and purification of peptides.
Colin T Mant, Yuxin Chen, Zhe Yan, Traian V Popa, James M Kovacs

Methods Mol Biol· August 2008

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Mixed-mode hydrophilic interaction/cation-exchange chromatography (HILIC/CEX) of peptides and proteins.
Colin T Mant, Robert S Hodges

J Sep Sci· August 2008

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Mixed-mode hydrophilic interaction/cation-exchange chromatography: separation of complex mixtures of peptides of varying charge and hydrophobicity.
Colin T Mant, Robert S Hodges

J Sep Sci· May 2008

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Ion-interaction CZE: the presence of high concentrations of ion-pairing reagents demonstrates the complex mechanisms involved in peptide separations.
Traian V Popa, Colin T Mant, Robert S Hodges

Electrophoresis· July 2007

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Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides.
Yuxin Chen, Michael T Guarnieri, Adriana I Vasil, Michael L Vasil, Colin T Mant

Antimicrob Agents Chemother· April 2007

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Requirements for prediction of peptide retention time in reversed-phase high-performance liquid chromatography: hydrophilicity/hydrophobicity of side-chains at the N- and C-termini of peptides are dramatically affected by the end-groups and location.
Brian Tripet, Dziuleta Cepeniene, James M Kovacs, Colin T Mant, Oleg V Krokhin

J Chromatogr A· February 2007

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Preparative reversed-phase high-performance liquid chromatography collection efficiency for an antimicrobial peptide on columns of varying diameters (1mm to 9.4mm I.D.).
Yuxin Chen, Colin T Mant, Robert S Hodges

J Chromatogr A· January 2007

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One-step purification of a recombinant protein from a whole cell extract by reversed-phase high-performance liquid chromatography.
Janine B Mills, Colin T Mant, Robert S Hodges

J Chromatogr A· November 2006

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