Publications by authors named "Miguel A Lanaspa"

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Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?
Richard J Johnson, Dean R Tolan, Dale Bredesen, Maria Nagel, Laura G Sánchez-Lozada, Mehdi Fini, Scott Burtis, Miguel A Lanaspa, David Perlmutter

Am J Clin Nutr· March 2023

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Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation.
Ana Andres-Hernando, Christina Cicerchi, Masanari Kuwabara, David J Orlicky, Laura Gabriela Sanchez-Lozada, Takahiko Nakagawa, Richard J Johnson, Miguel A Lanaspa

Nat Metab· September 2021

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Fructose and Uric Acid as Drivers of a Hyperactive Foraging Response: A Clue to Behavioral Disorders Associated with Impulsivity or Mania?
Richard J Johnson, William L Wilson, Sondra T Bland, Miguel A Lanaspa

May 2021

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Multilayered Interplay Between Fructose and Salt in Development of Hypertension.
Ozgur C Eren, Alberto Ortiz, Baris Afsar, Adrian Covic, Masanari Kuwabara, Miguel A Lanaspa, Richard J Johnson, Mehmet Kanbay

Hypertension· February 2019

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Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.
Thomas Jensen, Manal F Abdelmalek, Shelby Sullivan, Kristen J Nadeau, Melanie Green, Carlos Roncal, Takahiko Nakagawa, Masanari Kuwabara, Yuka Sato, Duk-Hee Kang

J Hepatol· May 2018

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Catechins for use in cardiovascular disease: Molecular mechanisms and contemporary bioassays.
Amy C Keller, Miguel A Lanaspa

J Pharm Biomed Anal· January 2026

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Water scarcity and conservation and their role in obesity in nature and in humans.
Richard J Johnson, Johanna Painer-Gigler, Szilvia Kalgeropoulu, Sylvain Giroud, Paul G Shiels, Miguel A Lanaspa

J Intern Med· December 2025

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Identification of a common ketohexokinase-dependent link driving alcohol intake and alcohol-associated liver disease in mice.
Ana Andres-Hernando, David J Orlicky, Gabriela E Garcia, Esteban C Loetz, Richard Montoya, Miguel A Lanaspa

Nat Metab· November 2025

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Fructose and follistatin potentiate acute MASLD during complete hepatic insulin resistance.
Rongya Tao, Oliver Stöhr, Ozlem Tok, Ana Andres-Hernando, Wei Qiu, Miguel A Lanaspa

Nat Commun· November 2025

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Hyperuricemia, A new cardiovascular risk.
Masanari Kuwabara, Ichiro Hisatome, Ryusuke Ae, Koki Kosami, Yuhei Aoki, Miguel A Lanaspa

Nutr Metab Cardiovasc Dis· March 2025

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Aldose reductase, fructose and fat production in the liver.
Peter Delannoy, Dean R Tolan, Miguel A Lanaspa, Iñigo San Millán, So Young Bae

Biochem J· March 2025

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Do microglia metabolize fructose in Alzheimer's disease?
Annalise M Sturno, James E Hassell, Miguel A Lanaspa, Kimberley D Bruce

J Neuroinflammation· March 2025

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Sodium-Glucose Cotransporter-2 Inhibitors and Uric Acid.
Laura G Sanchez-Lozada, Miguel A Lanaspa, Bernardo Rodriguez-Iturbe, Jared M Brown, Magdalena Madero

Nephron· March 2025

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Current updates and future perspectives in uric acid research, 2024.
Masanari Kuwabara, Ryusuke Ae, Koki Kosami, Mehmet Kanbay, Ana Andres-Hernando, Miguel A Lanaspa

Hypertens Res· February 2025

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A study on the early metabolic effects of salt and fructose consumption: the protective role of water.
Nuri Baris Hasbal, Cicek Nur Bakir, Said Incir, Dimitrie Siriopol, Laura G Sanchez-Lozada, Miguel A Lanaspa

Hypertens Res· July 2024

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Activation of AMPD2 drives metabolic dysregulation and liver disease in mice with hereditary fructose intolerance.
Ana Andres-Hernando, David J Orlicky, Masanari Kuwabara, Mehdi A Fini, Dean R Tolan, Miguel A Lanaspa

Commun Biol· July 2024

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The fructose survival hypothesis as a mechanism for unifying the various obesity hypotheses.
Richard J Johnson, Laura G Sánchez-Lozada, Miguel A Lanaspa

Obesity (Silver Spring)· January 2024

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Endogenous Fructose Production and Metabolism Drive Metabolic Dysregulation and Liver Disease in Mice with Hereditary Fructose Intolerance.
Ana Andres-Hernando, David J Orlicky, Masanari Kuwabara, Christina Cicerchi, Michelle Pedler, Miguel A Lanaspa

Nutrients· October 2023

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The fructose survival hypothesis for obesity.
Richard J Johnson, Miguel A Lanaspa, L Gabriela Sanchez-Lozada, Dean Tolan, Takahiko Nakagawa

Philos Trans R Soc Lond B Biol Sci· September 2023

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Sugar, salt, immunity and the cause of primary hypertension.
Laura G Sánchez-Lozada, Magdalena Madero, Marilda Mazzali, Daniel I Feig, Takahiko Nakagawa, Miguel A Lanaspa

Clin Kidney J· August 2023

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Fructose: A New Variable to Consider in SIADH and the Hyponatremia Associated With Long-Distance Running?
Richard J Johnson, S M Kurt Lee, Laura G Sánchez-Lozada, Mehmet Kanbay, Anip Bansal, Miguel A Lanaspa

Am J Kidney Dis· July 2023

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Update in uric acid, hypertension, and cardiovascular diseases.
Masanari Kuwabara, Takahide Kodama, Ryusuke Ae, Mehmet Kanbay, Ana Andres-Hernando, Miguel A Lanaspa

Hypertens Res· July 2023

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Fructose Metabolism and Metabolic Dysfunction in Adolescents and Young Adults.
Samir Softic, Miguel A Lanaspa, Brian DeBosch

Nutrients· July 2023

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Phosphate depletion in insulin-insensitive skeletal muscle drives AMPD activation and sarcopenia in chronic kidney disease.
Ana Andres-Hernando, Christina Cicerchi, Gabriela E Garcia, David J Orlicky, Peter Stenvinkel, Miguel A Lanaspa

iScience· April 2023

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Osthole Prevents Heart Damage Induced by Diet-Induced Metabolic Syndrome: Role of Fructokinase (KHK).
Fernando E García-Arroyo, Guillermo Gonzaga-Sánchez, Alejandro Silva-Palacios, Francisco Javier Roldán, María L Loredo-Mendoza, Miguel A Lanaspa

Antioxidants (Basel)· April 2023

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High Fructose Corn Syrup Accelerates Kidney Disease and Mortality in Obese Mice with Metabolic Syndrome.
Ana Andres-Hernando, David J Orlicky, Christina Cicerchi, Masanari Kuwabara, Gabriela E Garcia, Miguel A Lanaspa

Biomolecules· April 2023

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Fructose might be a clue to the origin of preeclampsia insights from nature and evolution.
Takahiko Nakagawa, Ana Andres-Hernando, Tomoki Kosugi, Laura G Sanchez-Lozada, Peter Stenvinkel, Miguel A Lanaspa

Hypertens Res· March 2023

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Responses to Hypoxia: How Fructose Metabolism and Hypoxia-Inducible Factor-1a Pathways Converge in Health and Disease.
Mehmet Kanbay, Alara Altıntas, Furkan Yavuz, Sidar Copur, Laura G Sanchez-Lozada, Miguel A Lanaspa

Curr Nutr Rep· March 2023

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Uric Acid and Chronic Kidney Disease: Still More to Do.
Richard J Johnson, Laura G Sanchez Lozada, Miguel A Lanaspa, Federica Piani, Claudio Borghi

Kidney Int Rep· February 2023

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