Publications by authors named "Colin W Fishwick"

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Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells.
Chloe G Myers, Hema Viswambharan, Natalie J Haywood, Katherine Bridge, Samuel Turvey, Colin Wg Fishwick

Mol Cell Endocrinol· December 2024

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Cyclic Boronates Inhibit All Classes of β-Lactamases.
Samuel T Cahill, Ricky Cain, David Y Wang, Christopher T Lohans, David W Wareham, Colin W G Fishwick

Antimicrob Agents Chemother· April 2017

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New Opportunities in the Structure-based Design of Anti-Protozoan Agents.
James A Gordon, Colin W G Fishwick, Martin J McPhillie

Curr Top Med Chem· February 2017

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Selective Phosphonylation of 5'-Adenosine Monophosphate (5'-AMP) via Pyrophosphite [PPi(III)].
Karl Kaye, David E Bryant, Katie E R Marriott, Shohei Ohara, Colin W G Fishwick

Orig Life Evol Biosph· November 2016

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Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists.
Emily A Caseley, Stephen P Muench, Colin W Fishwick, Lin-Hua Jiang

Biochem Pharmacol· September 2016

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Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates.
Jürgen Brem, Ricky Cain, Samuel Cahill, Michael A McDonough, Ian J Clifton, Colin W G Fishwick

Nat Commun· August 2016

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Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation.
Antony M Latham, Jayakanth Kankanala, Colin W G Fishwick, Sreenivasan Ponnambalam

Methods Mol Biol· May 2016

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In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis.
Antony M Latham, Jayakanth Kankanala, Gareth W Fearnley, Matthew C Gage, Mark T Kearney, Colin W G Fishwick

PLoS One· February 2016

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Natural and synthetic flavonoid modulation of TRPC5 channels.
Jacqueline Naylor, Aisling Minard, Hannah J Gaunt, Mohamed S Amer, Lesley A Wilson, Colin W G Fishwick

Br J Pharmacol· February 2016

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A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines.
Ronald Grigg, Elghareeb E Elboray, Sunisa Akkarasamiyo, Nutthawat Chuanopparat, H Ali Dondas, Colin W G Fishwick

Chem Commun (Camb)· January 2016

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Identification of a lead like inhibitor of the hepatitis C virus non-structural NS2 autoprotease.
Joseph Shaw, Mark Harris, Colin W G Fishwick

Antiviral Res· December 2015

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Refining the chemical toolbox to be fit for educational and practical purpose for drug discovery in the 21st Century.
Marco Lolli, Sarah Narramore, Colin W G Fishwick, Klaus Pors

Drug Discov Today· August 2015

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Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human.
Emily A Caseley, Stephen P Muench, Stephen A Baldwin, Katie Simmons, Colin W Fishwick

Bioorg Med Chem Lett· August 2015

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Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family.
Louise Kime, Helen A Vincent, Deena M A Gendoo, Stefanie S Jourdan, Colin W G Fishwick

Sci Rep· July 2015

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(±) cis-Bisamido epoxides: A novel series of potent FXIII-A inhibitors.
Craig A Avery, Richard J Pease, Kerrie Smith, May Boothby, Helen M Buckley, Colin W G Fishwick

Eur J Med Chem· June 2015

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Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease.
Joseph Shaw, Colin W G Fishwick, Mark Harris

Antiviral Res· May 2015

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Computational methods to identify new antibacterial targets.
Martin J McPhillie, Ricky M Cain, Sarah Narramore, Colin W G Fishwick, Katie J Simmons

Chem Biol Drug Des· January 2015

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The first small-molecule inhibitors of members of the ribonuclease E family.
Louise Kime, Helen A Vincent, Deena M A Gendoo, Stefanie S Jourdan, Colin W G Fishwick

Sci Rep· January 2015

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Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: structure based design, synthesis, SAR and antimicrobial activity.
Ian A Yule, Lloyd G Czaplewski, Stephanie Pommier, David T Davies, Sarah K Narramore, Colin W G Fishwick

Eur J Med Chem· October 2014

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Molecular mechanism of ligand recognition by membrane transport protein, Mhp1.
Katie J Simmons, Scott M Jackson, Florian Brueckner, Simon G Patching, Oliver Beckstein, Colin W G Fishwick

EMBO J· August 2014

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Applications of structure-based design to antibacterial drug discovery.
Ricky Cain, Sarah Narramore, Martin McPhillie, Katie Simmons, Colin W G Fishwick

Bioorg Chem· August 2014

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Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Marco Lolicato, Annalisa Bucchi, Cristina Arrigoni, Stefano Zucca, Marco Nardini, Colin W G Fishwick

Nat Chem Biol· June 2014

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Encapsulation of sodium alkyl sulfates by the cyclotriveratrylene-based, [Pd(6)L(8)](12+) stella octangula cage.
Nikki J Cookson, James J Henkelis, Richard J Ansell, Colin W G Fishwick, Michaele J Hardie

Dalton Trans· April 2014

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The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target.
Craig Wilkinson, Martin J McPhillie, Ying Zhou, Stuart Woods, Gustavo A Afanador, Colin W Fishwick

Bioorg Med Chem Lett· February 2014

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Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.
Gustavo A Afanador, Stephen P Muench, Martin McPhillie, Alina Fomovska, Arne Schön, Colin W Fishwick

Biochemistry· December 2013

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