Publications by authors named "Colin W Wright"

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Computational Insight into the Intercalating Properties of Cryptolepine.
George Ferguson, Louie Slocombe, John Lisgarten, David Lisgarten, Colin William Wright

ACS Omega· May 2025

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Evaluation of 43 species of Congolese medicinal plants used traditionally for the treatment of schistosomiasis leading to the isolation of an anti-schistosomal phaeophytin from Pseudolachnostylis maprouneifolia Pax.
Kalunga Muya, Mbuyi Kalonji, Numbi Wa Ilunga, Mwamba Maseho, Mbayo Kitambala, Colin W Wright

J Ethnopharmacol· October 2023

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Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer.
Kim Wong, Federico Abascal, Latasha Ludwig, Heike Aupperle-Lellbach, Julia Grassinger, Colin W Wright

Genome Biol· August 2023

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Machine learning enhances prediction of plants as potential sources of antimalarials.
Adam Richard-Bollans, Conal Aitken, Alexandre Antonelli, Cássia Bitencourt, David Goyder, Colin W Wright

Front Plant Sci· May 2023

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A methanolic extract of Zanthoxylum bungeanum modulates secondary metabolism regulator genes in Aspergillus flavus and shuts down aflatoxin production.
Asmaa Abbas, Colin W Wright, Nagwa El-Sawi, Tapani Yli-Mattila, Anssi M Malinen

Sci Rep· April 2022

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Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer.
Yabalu Z Abacha, Arnold Donkor Forkuo, Stephen Y Gbedema, Nimisha Mittal, Sabine Ottilie, Colin W Wright

Front Pharmacol· April 2022

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Review of the Phytochemistry and Biological Activity of Cissus incisa Leaves.
Deyani Nocedo-Mena, Adrián Alejandro Galván-Rodrigo, Colin W Wright, Pierluigi Caboni

Curr Top Med Chem· February 2022

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Anthelmintic activity and non-cytotoxicity of phaeophorbide-a isolated from the leaf of Spondias mombin L.
Abosede N Ogedengbe-Olowofoyeku, Isaiah O Ademola, Colin W Wright, Sunday O Idowu, Amos A Fatokun

J Ethnopharmacol· November 2021

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An Efficient Method for the Isolation of Toxins from Pteridium aquilinum and Evaluation of Ptaquiloside Against Cancer and Non-cancer Cells.
Courtney Williams, Simon J Allison, Roger M Phillips, Peter A Linley, Colin W Wright

Planta Med· August 2021

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Recent Advances in the Chemistry and Pharmacology of Cryptolepine.
Steven D Shnyder, Colin W Wright

Prog Chem Org Nat Prod· April 2021

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Bioactivity and cytotoxicity profiling of vincosamide and strictosamide, anthelmintic epimers from Sarcocephalus latifolius (Smith) Bruce leaf.
Segun A Aderibigbe, Sunday O Idowu, Ajibola A Olaniyi, Colin W Wright, Amos A Fatokun

J Ethnopharmacol· January 2021

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Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats.
Arnold Donkor Forkuo, Charles Ansah, David Pearson, Werner Gertsch, Amanda Cirello, Colin W Wright

BMC Pharmacol Toxicol· December 2017

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In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine.
Arnold Donkor Forkuo, Charles Ansah, Kwesi Boadu Mensah, Kofi Annan, Ben Gyan, Colin W Wright

Malar J· December 2017

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Identification of compounds with cytotoxic activity from the leaf of the Nigerian medicinal plant, Anacardium occidentale L. (Anacardiaceae).
Bamigboye J Taiwo, Amos A Fatokun, Olujide O Olubiyi, Olukemi T Bamigboye-Taiwo, Fanie R van Heerden, Colin W Wright

Bioorg Med Chem· April 2017

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Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
Irene Sola, Albert Artigas, Martin C Taylor, F Javier Pérez-Areales, Elisabet Viayna, Colin W Wright

Bioorg Med Chem· November 2016

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Prenylated flavanone derivatives isolated from Erythrina addisoniae are potent inducers of apoptotic cell death.
Claus M Passreiter, Anke-Katrin Suckow-Schnitker, Andreas Kulawik, Jonathan Addae-Kyereme, Colin W Wright

Phytochemistry· September 2015

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Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity.
Irene Sola, Sílvia Castellà, Elisabet Viayna, Carles Galdeano, Martin C Taylor, Colin W Wright

Bioorg Med Chem· August 2015

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Clerodane diterpenes from Polyalthia longifolia (Sonn) Thw. var. pendula: Potential antimalarial agents for drug resistant Plasmodium falciparum infection.
Stephen Y Gbedema, Marcel T Bayor, Kofi Annan, Colin W Wright

J Ethnopharmacol· July 2015

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Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Irene Sola, Albert Artigas, Martin C Taylor, Stephen Y Gbedema, Belén Pérez, Colin W Wright

Bioorg Med Chem Lett· December 2014

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Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine.
Olumayokun A Olajide, Harsharan S Bhatia, Antonio C P de Oliveira, Colin W Wright, Bernd L Fiebich

Evid Based Complement Alternat Med· July 2013

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Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: possible involvement of NF-κB and p38 MAPK inhibition.
Olumayokun A Olajide, Harsharan S Bhatia, Antonio C P de Oliveira, Colin W Wright, Bernd L Fiebich

Eur J Med Chem· May 2013

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Screening Indian plant species for antiplasmodial properties--ethnopharmacological compared with random selection.
Venkata Siva Satyanarayana Kantamreddi, Colin W Wright

Phytother Res· December 2012

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Antileishmanial activity of cryptolepine analogues and apoptotic effects of 2,7-dibromocryptolepine against Leishmania donovani promastigotes.
Sudipta Hazra, Subhalakshmi Ghosh, Sukalyani Debnath, Scott Seville, Vijay Kumar Prajapati, Colin W Wright

Parasitol Res· July 2012

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Metabolism of cryptolepine and 2-fluorocryptolepine by aldehyde oxidase.
J Godfrey P Stell, Richard T Wheelhouse, Colin W Wright

J Pharm Pharmacol· February 2012

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Complete NMR assignments of tubulosine.
Venkata Siva Satyanarayana Kantamreddia, Colin W Wright

Nat Prod Commun· January 2012

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