Publications by authors named "Colm Farrell"

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Population pharmacokinetics and exposure-response relationships of maribavir in transplant recipients with cytomegalovirus infection.
Ivy H Song, Grace Chen, Siobhan Hayes, Colm Farrell, Claudia Jomphe

J Pharmacokinet Pharmacodyn· December 2024

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Belantamab mafodotin concentration-QTc relationships in patients with relapsed or refractory multiple myeloma from the DREAMM-1 and -2 studies.
Roxanne C Jewell, Richard J Mills, Colm Farrell, Sandra A G Visser

Br J Clin Pharmacol· October 2024

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Model-informed Evidence for Clinical Non-inferiority of Every-2-Weeks Versus Standard Weekly Dosing Schedule of Cetuximab in Metastatic Colorectal Cancer.
Ana-Marija Milenković-Grišić, Siobhán Hayes, Colm Farrell, Yoshihiro Kuroki, Mauro Bertolino

Clin Pharmacol Ther· October 2024

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Safety, pharmacokinetics, and pharmacodynamics of intravenous ferric carboxymaltose in children with iron deficiency anemia.
Bartosz Korczowski, Colm Farrell, Mark Falone, Nicole Blackman, Trudy Rodgers

Pediatr Res· October 2023

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Population pharmacokinetics of atacicept in systemic lupus erythematosus: An analysis of three clinical trials.
Maria Pitsiu, Özkan Yalkinoglu, Colm Farrell, Pascal Girard, Cristina Vazquez-Mateo

CPT Pharmacometrics Syst Pharmacol· August 2023

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Pediatric Population Pharmacokinetic Modeling and Exposure-Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data.
Malek Okour, Mita M Thapar, Colm Farrell, Mary Ann Lukas, Maurice Beghetti

J Clin Pharmacol· May 2023

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Population pharmacokinetic modeling and simulation of maribavir to support dose selection and regulatory approval in adolescents with posttransplant refractory cytomegalovirus.
Kefeng Sun, Siobhan Hayes, Colm Farrell, Ivy H Song

CPT Pharmacometrics Syst Pharmacol· May 2023

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Population pharmacokinetics of recombinant human C1 esterase inhibitor in children with hereditary angioedema.
Siobhán Hayes, Colm Farrell, Anurag Relan, John Anderson

Ann Allergy Asthma Immunol· June 2021

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A Physiologically Based Pharmacokinetic Model to Predict Potential Drug-Drug Interactions and Inform Dosing of Acumapimod, an Oral p38 MAPK Inhibitor.
Alex Agyemang, Colm Farrell, William Moore, Jacqueline Parkin

CPT Pharmacometrics Syst Pharmacol· January 2021

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Population Pharmacokinetic Analysis of Fluticasone Furoate/Umeclidinium Bromide/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease.
Rashmi Mehta, Colm Farrell, Siobhán Hayes, Ruby Birk, Malek Okour

Clin Pharmacokinet· January 2020

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Oliceridine, a Novel G Protein-Biased Ligand at the μ-Opioid Receptor, Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. II: Simulation of Potential Phase 3 Study Designs Using a Pharmacokinetic/Pharmacodynamic Model.
Michael J Fossler, Brian M Sadler, Colm Farrell, David A Burt, Maria Pitsiu

J Clin Pharmacol· June 2018

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Oliceridine (TRV130), a Novel G Protein-Biased Ligand at the μ-Opioid Receptor, Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. I: Development of a Pharmacokinetic/Pharmacodynamic Model.
Michael J Fossler, Brian M Sadler, Colm Farrell, David A Burt, Maria Pitsiu

J Clin Pharmacol· June 2018

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A population pharmacokinetic meta-analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects.
Alena Y Edwards, Anna Elgart, Colm Farrell, Ofra Barnett-Griness, Laura Rabinovich-Guilatt

Br J Clin Pharmacol· September 2017

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Population pharmacokinetic and pharmacodynamic analyses of safinamide in subjects with Parkinson's disease.
Luca Loprete, Chiara Leuratti, Carlo Cattaneo, Mita M Thapar, Colm Farrell

Pharmacol Res Perspect· October 2016

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Population Pharmacokinetic and Pharmacodynamic Modeling and Effects on Platelet Counts of Different Dosages of Eltrombopag in Chinese Patients With Chronic Primary Immune Thrombocytopenia.
Kai Wu, Mita Thapar, Colm Farrell, Siobhan Hayes, Haiyi Guo

Clin Ther· July 2015

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Proposed closure of Inverness disease surveillance centre.
Graeme Swanson, Hamish MacGregor-Robertson, Douglas Swaffield, Kenny Johnston, Colm Farrell

Vet Rec· July 2015

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Modeling and simulation support eltrombopag dosing in thrombocytopenic patients with chronic HCV infection.
Jianping Zhang, Mita Thapar, Colm Farrell, Mary B Wire

Pharm Res· June 2015

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Development of in vitro-in vivo correlation for extended-release niacin after administration of hypromellose-based matrix formulations to healthy volunteers.
Filippos Kesisoglou, Stefaan Rossenu, Colm Farrell, Michiel Van Den Heuvel, Marita Prohn

J Pharm Sci· November 2014

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Population pharmacokinetic/pharmacodynamic modelling of eltrombopag in healthy volunteers and subjects with chronic liver disease.
Colm Farrell, Siobhan C Hayes, Mary Wire, Jianping Zhang

Br J Clin Pharmacol· March 2014

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Population pharmacokinetics of recombinant human C1 inhibitor in patients with hereditary angioedema.
Colm Farrell, Siobhan Hayes, Anurag Relan, Edwin S van Amersfoort, Rienk Pijpstra

Br J Clin Pharmacol· December 2013

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Population pharmacokinetics of farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer.
Colm Farrell, Charles Schweizer, Jason Wustner, Susan Weil, Masayuki Namiki

Cancer Chemother Pharmacol· November 2012

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Challenges and opportunities in establishing scientific and regulatory standards for assuring therapeutic equivalence of modified release products: workshop summary report.
Mei-Ling Chen, Vinod P Shah, Derek Ganes, Kamal K Midha, James Caro, Colm Farrell

AAPS J· September 2010

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Challenges and opportunities in establishing scientific and regulatory standards for determining therapeutic equivalence of modified-release products: Workshop summary report.
Mei-Ling Chen, Vinod P Shah, Derek Ganes, Kamal K Midha, James Caro, Colm Farrell

Clin Ther· September 2010

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Challenges and opportunities in establishing scientific and regulatory standards for assuring therapeutic equivalence of modified-release products: workshop summary report.
Mei-Ling Chen, Vinod P Shah, Derek Ganes, Kamal K Midha, James Caro, Colm Farrell

Eur J Pharm Sci· May 2010

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Population pharmacokinetics of telbivudine and determination of dose adjustment for patients with renal impairment.
Xiao-Jian Zhou, June Ke, William M Sallas, Colm Farrell, Douglas L Mayers

J Clin Pharmacol· June 2009

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