Publications by authors named "Pascal Girard"

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Frequency Coding of Multisensory Integration in the Local Field Potentials of the Medial Pulvinar.
Anne-Laure Vittek, Cécile Juan, Corentin Gaillard, Manuel Mercier, Pascal Girard

Eur J Neurosci· September 2025

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Historical Use of Markov Model and Posterior Predictive Checks in Pharmacometrics.
Pascal Girard, Helen Kastrissios

CPT Pharmacometrics Syst Pharmacol· May 2025

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Generative models for synthetic data generation: application to pharmacokinetic/pharmacodynamic data.
Yulun Jiang, Alberto García-Durán, Idris Bachali Losada, Pascal Girard, Nadia Terranova

J Pharmacokinet Pharmacodyn· December 2024

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Model-informed Evidence for Clinical Non-inferiority of Every-2-Weeks Versus Standard Weekly Dosing Schedule of Cetuximab in Metastatic Colorectal Cancer.
Ana-Marija Milenković-Grišić, Siobhán Hayes, Colm Farrell, Yoshihiro Kuroki, Mauro Bertolino, Pascal Girard

Clin Pharmacol Ther· October 2024

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Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non-small cell lung cancer based on bintrafusp alfa trials.
Ana-Marija Milenković-Grišić, Nadia Terranova, Diane R Mould, Yulia Vugmeyster, Thomas Mrowiec, Pascal Girard

CPT Pharmacometrics Syst Pharmacol· January 2024

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A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non-small cell lung cancer.
Han Liu, Ana-Marija Milenković-Grišić, Sreenath M Krishnan, Siv Jönsson, Lena E Friberg, Pascal Girard

CPT Pharmacometrics Syst Pharmacol· November 2023

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Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy.
Perrine Courlet, Daniel Abler, Monia Guidi, Pascal Girard, Federico Amato

CPT Pharmacometrics Syst Pharmacol· August 2023

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Population pharmacokinetics of atacicept in systemic lupus erythematosus: An analysis of three clinical trials.
Maria Pitsiu, Özkan Yalkinoglu, Colm Farrell, Pascal Girard, Cristina Vazquez-Mateo

CPT Pharmacometrics Syst Pharmacol· August 2023

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Semiautomated Pipeline to Quantify Tumor Evolution From Real-World Positron Emission Tomography/Computed Tomography Imaging.
Daniel Abler, Perrine Courlet, Matthieu Dietz, Roberto Gatta, Pascal Girard

JCO Clin Cancer Inform· May 2023

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Multisensory integration in neurons of the medial pulvinar of macaque monkey.
Anne-Laure Vittek, Cécile Juan, Lionel G Nowak, Pascal Girard, Céline Cappe

Cereb Cortex· April 2023

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Disease trajectory of SLE clinical endpoints and covariates affecting disease severity and probability of response: Analysis of pooled patient-level placebo (Standard-of-Care) data to enable model-informed drug development.
Kosalaram Goteti, Jonathan French, Ramon Garcia, Ying Li, Florence Casset-Semanaz, Pascal Girard

CPT Pharmacometrics Syst Pharmacol· February 2023

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Determination of a clinically effective evobrutinib dose: Exposure-response analyses of a phase II relapsing multiple sclerosis study.
Orestis Papasouliotis, David Mitchell, Pascal Girard, Fernando Dangond, Martin Dyroff

Clin Transl Sci· December 2022

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Population pharmacokinetic and pharmacodynamic modeling of evobrutinib in healthy adult participants.
Orestis Papasouliotis, David Mitchell, Pascal Girard, Martin Dyroff

Clin Transl Sci· December 2022

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Designing phase I oncology dose escalation using dose-exposure-toxicity models as a complementary approach to model-based dose-toxicity models.
Kristyn Pantoja, Shankar Lanke, Alain Munafo, Anja Victor, Christina Habermehl, Pascal Girard

CPT Pharmacometrics Syst Pharmacol· October 2022

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Predicting disease activity in patients with multiple sclerosis: An explainable machine-learning approach in the Mavenclad trials.
Sreetama Basu, Alain Munafo, Ali-Frederic Ben-Amor, Sanjeev Roy, Pascal Girard

CPT Pharmacometrics Syst Pharmacol· July 2022

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Exposure-response analyses for the MET inhibitor tepotinib including patients in the pivotal VISION trial: support for dosage recommendations.
Wenyuan Xiong, Sofia Friberg Hietala, Joakim Nyberg, Orestis Papasouliotis, Andreas Johne, Pascal Girard

Cancer Chemother Pharmacol· July 2022

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Population pharmacokinetic analysis of tepotinib, an oral MET kinase inhibitor, including data from the VISION study.
Wenyuan Xiong, Orestis Papasouliotis, E Niclas Jonsson, Rainer Strotmann, Pascal Girard

Cancer Chemother Pharmacol· May 2022

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Population pharmacokinetic model selection assisted by machine learning.
Emeric Sibieude, Akash Khandelwal, Pascal Girard, Jan S Hesthaven, Nadia Terranova

J Pharmacokinet Pharmacodyn· April 2022

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Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab.
Ana-Marija Grisic, Wenyuan Xiong, Lénaïg Tanneau, Siv Jönsson, Lena E Friberg, Pascal Girard

Clin Cancer Res· April 2022

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Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab.
Nadia Terranova, Jonathan French, Haiqing Dai, Matthew Wiens, Akash Khandelwal, Pascal Girard

CPT Pharmacometrics Syst Pharmacol· March 2022

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Optimization of dose selection using multiple surrogates of toxicity as a continuous variable in phase I cancer trial.
Se Yoon Lee, Alain Munafo, Pascal Girard, Kosalaram Goteti

Contemp Clin Trials· February 2022

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Relevance of primary lesion location, tumour heterogeneity and genetic mutation demonstrated through tumour growth inhibition and overall survival modelling in metastatic colorectal cancer.
Diego Vera-Yunca, Zinnia P Parra-Guillen, Pascal Girard, Iñaki F Trocóniz, Nadia Terranova

Br J Clin Pharmacol· January 2022

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Fast screening of covariates in population models empowered by machine learning.
Emeric Sibieude, Akash Khandelwal, Jan S Hesthaven, Pascal Girard, Nadia Terranova

J Pharmacokinet Pharmacodyn· August 2021

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Translational pharmacokinetic-pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose.
Wenyuan Xiong, Manja Friese-Hamim, Andreas Johne, Christopher Stroh, Manfred Klevesath, Pascal Girard

CPT Pharmacometrics Syst Pharmacol· May 2021

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Location and temporal memory of objects declines in aged marmosets (Callithrix jacchus).
Vanessa De Castro, Pascal Girard

Sci Rep· April 2021

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