Publications by authors named "Perrine Courlet"

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Precemtabart tocentecan, an anti-CEACAM5 antibody-drug conjugate, in metastatic colorectal cancer: a phase 1 trial.
Scott Kopetz, Valentina Boni, Ken Kato, Kanwal P S Raghav, Maria Vieito, Perrine Courlet

Nat Med· October 2025

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Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data.
Mohamed Maiga, Laurent Dembele, Perrine Courlet, Akash Khandelwal, Antoine Dara

Nat Commun· September 2024

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Semi-mechanistic population pharmacokinetic/pharmacodynamic modeling of a elongation factor 2 inhibitor cabamiquine for prevention and cure of malaria.
Perrine Courlet, Justin J Wilkins, Claude Oeuvray, Wei Gao, Akash Khandelwal

Antimicrob Agents Chemother· December 2023

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Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy.
Perrine Courlet, Daniel Abler, Monia Guidi, Pascal Girard, Federico Amato

CPT Pharmacometrics Syst Pharmacol· August 2023

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Population pharmacokinetic modelling to characterize the effect of chronic kidney disease on tenofovir exposure after tenofovir alafenamide administration.
Paul Thoueille, Susana Alves Saldanha, Vincent Desfontaine, Katharina Kusejko, Perrine Courlet

J Antimicrob Chemother· June 2023

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Semiautomated Pipeline to Quantify Tumor Evolution From Real-World Positron Emission Tomography/Computed Tomography Imaging.
Daniel Abler, Perrine Courlet, Matthieu Dietz, Roberto Gatta, Pascal Girard

JCO Clin Cancer Inform· May 2023

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Adherence to the CDK 4/6 Inhibitor Palbociclib and Omission of Dose Management Supported by Pharmacometric Modelling as Part of the OpTAT Study.
Carole Bandiera, Isabella Locatelli, Perrine Courlet, Evelina Cardoso, Khalil Zaman

Cancers (Basel)· January 2023

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Population Pharmacokinetics of Palbociclib and Its Correlation with Clinical Efficacy and Safety in Patients with Advanced Breast Cancer.
Perrine Courlet, Evelina Cardoso, Carole Bandiera, Athina Stravodimou, Jean-Philippe Zurcher

Pharmaceutics· June 2022

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Model-based meta-analysis of salbutamol pharmacokinetics and practical implications for doping control.
Perrine Courlet, Thierry Buclin, Jérôme Biollaz, Irene Mazzoni, Olivier Rabin

CPT Pharmacometrics Syst Pharmacol· April 2022

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Pharmacokinetic parameters and weight change in HIV patients newly switched to dolutegravir-based regimens in SIMPL'HIV clinical trial.
Perrine Courlet, Charlotte Barbieux, Delphine Sculier, Gilles Wandeler, Marcel Stoeckle

Br J Clin Pharmacol· November 2021

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Population pharmacokinetic modelling to quantify the magnitude of drug-drug interactions between amlodipine and antiretroviral drugs.
Perrine Courlet, Monia Guidi, Susana Alves Saldanha, Matthias Cavassini, Marcel Stoeckle

Eur J Clin Pharmacol· July 2021

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Physiologically-Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV.
Felix Stader, Perrine Courlet, Laurent A Decosterd, Manuel Battegay, Catia Marzolini

Clin Pharmacol Ther· April 2021

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Pharmacokinetic/Pharmacodynamic Modelling to Describe the Cholesterol Lowering Effect of Rosuvastatin in People Living with HIV.
Perrine Courlet, Monia Guidi, Susana Alves Saldanha, Felix Stader, Anna Traytel

Clin Pharmacokinet· March 2021

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Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation.
Felix Stader, Perrine Courlet, Hannah Kinvig, Manuel Battegay, Laurent A Decosterd

Br J Clin Pharmacol· February 2021

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Clinical Data Combined With Modeling and Simulation Indicate Unchanged Drug-Drug Interaction Magnitudes in the Elderly.
Felix Stader, Perrine Courlet, Hannah Kinvig, Melissa A Penny, Laurent A Decosterd

Clin Pharmacol Ther· February 2021

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Influence of Drug-Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV.
Perrine Courlet, Laurent A Decosterd, Susana Alves Saldanha, Matthias Cavassini, Felix Stader

Clin Pharmacokinet· August 2020

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Real-life management of drug-drug interactions between antiretrovirals and statins.
Perrine Courlet, Françoise Livio, Susana Alves Saldanha, Alexandra Scherrer, Manuel Battegay

J Antimicrob Chemother· July 2020

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Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.
Perrine Courlet, Susana Alves Saldanha, Matthias Cavassini, Catia Marzolini, Eva Choong

J Mass Spectrom· June 2020

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Aging does not impact drug--drug interaction magnitudes with antiretrovirals.
Felix Stader, Laurent Decosterd, Marcel Stoeckle, Matthias Cavassini, Manuel Battegay, Perrine Courlet

AIDS· May 2020

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Population Pharmacokinetics/Pharmacodynamics of Dabrafenib Plus Trametinib in Patients with BRAF-Mutated Metastatic Melanoma.
David Balakirouchenane, Sarah Guégan, Chantal Csajka, Anne Jouinot, Valentine Heidelberger, Perrine Courlet

Cancers (Basel)· April 2020

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Pharmacokinetic profiles of boosted darunavir, dolutegravir and lamivudine in aging people living with HIV.
Perrine Courlet, Felix Stader, Monia Guidi, Susana Alves Saldanha, Marcel Stoeckle

AIDS· January 2020

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Polypharmacy, Drug-Drug Interactions, and Inappropriate Drugs: New Challenges in the Aging Population With HIV.
Perrine Courlet, Françoise Livio, Monia Guidi, Matthias Cavassini, Manuel Battegay

Open Forum Infect Dis· December 2019

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Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting.
Catalina Barcelo, Manel Aouri, Perrine Courlet, Monia Guidi, Dominique L Braun

J Antimicrob Chemother· September 2019

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Escitalopram population pharmacokinetics in people living with human immunodeficiency virus and in the psychiatric population: Drug-drug interactions and probability of target attainment.
Perrine Courlet, Monia Guidi, Anaïs Glatard, Susana Alves Saldanha, Matthias Cavassini

Br J Clin Pharmacol· September 2019

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UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
Perrine Courlet, Dany Spaggiari, Vincent Desfontaine, Matthias Cavassini, Susana Alves Saldanha

J Chromatogr B Analyt Technol Biomed Life Sci· September 2019

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