Publications by authors named "Connor A Howe"

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Cerebral oxygen extraction across different exercise intensities: Role of arterial .
L Madden Brewster, Travis Dylan Gibbons, Hannah Grace Caldwell, Connor A Howe, Jennifer S Duffy

Exp Physiol· December 2025

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Lactate accumulates in the cerebrospinal fluid after prolonged exercise.
Jennifer S Duffy, Justin A Monteleone, Jay Mjr Carr, Connor A Howe, Jodie Koep

J Cereb Blood Flow Metab· December 2025

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Brain glucose extraction is fixed at 10% despite twofold variability in resting cerebral blood flow in healthy humans.
Jennifer S Duffy, Hannah G Caldwell, Ryan L Hoiland, Connor A Howe, Kurt J Smith

J Cereb Blood Flow Metab· December 2025

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Preferential lactate metabolism in the human brain during exogenous and endogenous hyperlactataemia.
Jodie L Koep, Jennifer S Duffy, Jay M J R Carr, Madden L Brewster, Jordan D Bird, Connor A Howe

J Physiol· November 2025

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Cerebral blood flow in Andean children and adolescents living above 5,000 m.
Connor A Howe, Samuel Verges, Daniela Nowak-Flück, Jack S Talbot, Benoit Champigneulle

J Neurophysiol· April 2025

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Acute selective serotonin-reuptake inhibition elevates basal ventilation and attenuates the rebreathing ventilatory response, independent of cerebral perfusion.
Jay M J R Carr, Jodie Koep, L Madden Brewster, Ayechew Getu, Jonah C Dizon, Connor A Howe

J Appl Physiol (1985)· February 2025

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Haemoconcentration and cerebral blood flow: absence of evidence is not evidence of absence.
Connor A Howe

J Physiol· November 2024

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Micro- and macrovascular function in the highest city in the world: a cross sectional study.
Yann Savina, Aurélien P Pichon, Lucas Lemaire, Connor A Howe, Mathilde Ulliel-Roche

Lancet Reg Health Am· October 2024

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Evidence for direct CO -mediated alterations in cerebral oxidative metabolism in humans.
Hannah G Caldwell, Ryan L Hoiland, Anthony R Bain, Connor A Howe, Jay M J R Carr

Acta Physiol (Oxf)· September 2024

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Hemorheological, cardiorespiratory, and cerebrovascular effects of pentoxifylline following acclimatization to 3,800 m.
Andrew R Steele, Connor A Howe, Travis D Gibbons, Katharine Foster, Alexandra M Williams

Am J Physiol Heart Circ Physiol· March 2024

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Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and -nitrosothiol mediated signal transduction.
Ryan L Hoiland, David B MacLeod, Benjamin S Stacey, Hannah G Caldwell, Connor A Howe

J Cereb Blood Flow Metab· September 2023

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Lifelong exposure to high-altitude hypoxia in humans is associated with improved redox homeostasis and structural-functional adaptations of the neurovascular unit.
Benjamin S Stacey, Ryan L Hoiland, Hannah G Caldwell, Connor A Howe, Tyler Vermeulen

J Physiol· March 2023

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Impact of Oxygen Supplementation on Brachial Artery Hemodynamics and Vascular Function During Ascent to 5,050 m.
Gustavo A Vizcardo-Galindo, Connor A Howe, Ryan L Hoiland, Howard H Carter, Christopher K Willie

High Alt Med Biol· March 2023

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Cerebral O and CO transport in isovolumic haemodilution: Compensation of cerebral delivery of O and maintenance of cerebrovascular reactivity to CO.
Jay Mjr Carr, Philip N Ainslie, David B MacLeod, Joshua C Tremblay, Daniela Nowak-Flück, Connor A Howe

J Cereb Blood Flow Metab· January 2023

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Brachial artery responses to acute hypercapnia: The roles of shear stress and adrenergic tone.
Jay M J R Carr, Philip N Ainslie, Connor A Howe, Travis D Gibbons, Michael M Tymko

Exp Physiol· December 2022

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Cerebral endothelium-dependent function and reactivity to hypercapnia: the role of α-adrenoreceptors.
Jay M J R Carr, Connor A Howe, Travis D Gibbons, Michael M Tymko, Andrew R Steele

J Appl Physiol (1985)· December 2022

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The human blood transcriptome exhibits time-of-day-dependent response to hypoxia: Lessons from the highest city in the world.
Gal Manella, Saar Ezagouri, Benoit Champigneulle, Jonathan Gaucher, Monique Mendelson, Connor A Howe

Cell Rep· August 2022

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Global REACH 2018: Characterizing Acid-Base Balance Over 21 Days at 4,300 m in Lowlanders.
Andrew R Steele, Philip N Ainslie, Rachel Stone, Kaitlyn Tymko, Courtney Tymko, Connor A Howe

High Alt Med Biol· June 2022

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Global Research Expedition on Altitude-related Chronic Health 2018 Iron Infusion at High Altitude Reduces Hypoxic Pulmonary Vasoconstriction Equally in Both Lowlanders and Healthy Andean Highlanders.
Alexander Patrician, Tony Dawkins, Geoff B Coombs, Benjamin Stacey, Christopher Gasho, Connor A Howe

Chest· April 2022

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Trans-cerebral HCO and PCO exchange during acute respiratory acidosis and exercise-induced metabolic acidosis in humans.
Hannah G Caldwell, Ryan L Hoiland, Kurt J Smith, Patrice Brassard, Anthony R Bain, Connor A Howe

J Cereb Blood Flow Metab· April 2022

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Nitric oxide contributes to cerebrovascular shear-mediated dilatation but not steady-state cerebrovascular reactivity to carbon dioxide.
Ryan L Hoiland, Hannah G Caldwell, Jay M J R Carr, Connor A Howe, Benjamin S Stacey

J Physiol· March 2022

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Acid-base balance at high altitude in lowlanders and indigenous highlanders.
Michael M Tymko, Christopher K Willie, Connor A Howe, Ryan L Hoiland, Rachel M Stone

J Appl Physiol (1985)· February 2022

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The influence of hemoconcentration on hypoxic pulmonary vasoconstriction in acute, prolonged, and lifelong hypoxemia.
Mike Stembridge, Ryan L Hoiland, Alexandra M Williams, Connor A Howe, Joseph Donnelly

Am J Physiol Heart Circ Physiol· October 2021

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Alterations in arterial CO rather than pH affect the kinetics of neurovascular coupling in humans.
Hannah G Caldwell, Connor A Howe, Ryan L Hoiland, Jay M J R Carr, Carter J Chalifoux

J Physiol· August 2021

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Temporal changes in pulmonary gas exchange efficiency when breath-hold diving below residual volume.
Alexander Patrician, Boris Spajić, Christopher Gasho, Hannah G Caldwell, Tony Dawkins, Connor A Howe

Exp Physiol· April 2021

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