Publications by authors named "Conrad A Nieduszynski"

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Most human DNA replication initiation is dispersed throughout the genome with only a minority within previously identified initiation zones.
Jamie T Carrington, Rosemary H C Wilson, Eduardo de La Vega, Sathish Thiyagarajan, Tom Barker, Conrad A Nieduszynski

Genome Biol· May 2025

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Schizosaccharomyces versatilis represents a distinct evolutionary lineage of fission yeast.
Graham J Etherington, Elisa Gomez Gil, Wilfried Haerty, Snezhana Oliferenko, Conrad A Nieduszynski

Yeast· March 2024

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Telomere-to-telomere Schizosaccharomyces japonicus genome assembly reveals hitherto unknown genome features.
Graham J Etherington, Pei-Shang Wu, Snezhana Oliferenko, Frank Uhlmann, Conrad A Nieduszynski

Yeast· March 2024

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Design, construction, and functional characterization of a tRNA neochromosome in yeast.
Daniel Schindler, Roy S K Walker, Shuangying Jiang, Aaron N Brooks, Yun Wang, Conrad A Nieduszynski

Cell· November 2023

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Systematic Analysis of Copy Number Variations in the Pathogenic Yeast Candida parapsilosis Identifies a Gene Amplification in That is Associated with Drug Resistance.
Sean A Bergin, Fang Zhao, Adam P Ryan, Carolin A Müller, Conrad A Nieduszynski

mBio· October 2022

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Tos4 mediates gene expression homeostasis through interaction with HDAC complexes independently of H3K56 acetylation.
Sophie L Cooke, Barbara L Soares, Carolin A Müller, Conrad A Nieduszynski, Francisco M Bastos de Oliveira

J Biol Chem· August 2021

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Effectiveness of glass beads for plating cell cultures.
Alidivinas Prusokas, Michelle Hawkins, Conrad A Nieduszynski, Renata Retkute

Phys Rev E· May 2021

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Sir2 mitigates an intrinsic imbalance in origin licensing efficiency between early- and late-replicating euchromatin.
Timothy Hoggard, Carolin A Müller, Conrad A Nieduszynski, Michael Weinreich, Catherine A Fox

Proc Natl Acad Sci U S A· June 2020

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DNA copy-number measurement of genome replication dynamics by high-throughput sequencing: the sort-seq, sync-seq and MFA-seq family.
Dzmitry G Batrakou, Carolin A Müller, Rosemary H C Wilson, Conrad A Nieduszynski

Nat Protoc· March 2020

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The Beacon Calculus: A formal method for the flexible and concise modelling of biological systems.
Michael A Boemo, Luca Cardelli, Conrad A Nieduszynski

PLoS Comput Biol· March 2020

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Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads.
Carolin A Müller, Michael A Boemo, Paolo Spingardi, Benedikt M Kessler, Skirmantas Kriaucionis, Conrad A Nieduszynski

Nat Methods· May 2019

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Interspecies conservation of organisation and function between nonhomologous regional centromeres.
Pin Tong, Alison L Pidoux, Nicholas R T Toda, Ryan Ard, Harald Berger, Conrad A Nieduszynski

Nat Commun· May 2019

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Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals.
Anne D Donaldson, Conrad A Nieduszynski

Genome Biol· May 2019

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Cohesin-Mediated Genome Architecture Does Not Define DNA Replication Timing Domains.
Phoebe Oldach, Conrad A Nieduszynski

Genes (Basel)· March 2019

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Bayesian inference of origin firing time distributions, origin interference and licencing probabilities from Next Generation Sequencing data.
Alina Bazarova, Conrad A Nieduszynski, Ildem Akerman, Nigel J Burroughs

Nucleic Acids Res· March 2019

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Rapid high-resolution measurement of DNA replication timing by droplet digital PCR.
Dzmitry G Batrakou, Emma D Heron, Conrad A Nieduszynski

Nucleic Acids Res· November 2018

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Evolution of Genome Architecture in Archaea: Spontaneous Generation of a New Chromosome in Haloferax volcanii.
Darya Ausiannikava, Laura Mitchell, Hannah Marriott, Victoria Smith, Michelle Hawkins, Conrad A Nieduszynski

Mol Biol Evol· August 2018

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Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast.
Sylwia Kedziora, Vamsi K Gali, Rosemary H C Wilson, Kate R M Clark, Conrad A Nieduszynski

Nucleic Acids Res· May 2018

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Investigating the role of Rts1 in DNA replication initiation.
Ana B A Wallis, Conrad A Nieduszynski

Wellcome Open Res· March 2018

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DNA replication timing influences gene expression level.
Carolin A Müller, Conrad A Nieduszynski

J Cell Biol· July 2017

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Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.
Yue Shen, Yun Wang, Tai Chen, Feng Gao, Jianhui Gong, Conrad A Nieduszynski

Science· March 2017

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A global profile of replicative polymerase usage.
Yasukazu Daigaku, Andrea Keszthelyi, Carolin A Müller, Izumi Miyabe, Tony Brooks, Conrad A Nieduszynski

Nat Struct Mol Biol· March 2015

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The dynamics of genome replication using deep sequencing.
Carolin A Müller, Michelle Hawkins, Renata Retkute, Sunir Malla, Ray Wilson, Conrad A Nieduszynski

Nucleic Acids Res· January 2014

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Accelerated growth in the absence of DNA replication origins.
Michelle Hawkins, Sunir Malla, Martin J Blythe, Conrad A Nieduszynski, Thorsten Allers

Nature· November 2013

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High-resolution replication profiles define the stochastic nature of genome replication initiation and termination.
Michelle Hawkins, Renata Retkute, Carolin A Müller, Nazan Saner, Tomoyuki U Tanaka, Conrad A Nieduszynski

Cell Rep· November 2013

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