Publications by authors named "Constance Brinckerhoff"

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Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.
Jennifer A Lo, Masayoshi Kawakubo, Vikram R Juneja, Mack Y Su, Tal H Erlich, Constance E Brinckerhoff

Sci Transl Med· February 2021

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A TLR7 agonist strengthens T and NK cell function during BRAF-targeted therapy in a preclinical melanoma model.
Lydia Bellmann, Giuseppe Cappellano, Johanna F Schachtl-Riess, Anastasia Prokopi, Athanasios Seretis, Constance E Brinckerhoff

Int J Cancer· March 2020

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Cancer Stem Cells (CSCs) in melanoma: There's smoke, but is there fire?
Constance E Brinckerhoff

J Cell Physiol· October 2017

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The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells.
Chery A Whipple, Andrea Boni, Jan L Fisher, Thomas H Hampton, Gregory J Tsongalis, Constance E Brinckerhoff

Melanoma Res· June 2016

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What are the therapeutic implications of increased collagen expression in melanoma cells treated with vemurafenib?
Constance E Brinckerhoff

Melanoma Manag· March 2016

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CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity.
Molly H Jenkins, Constance E Brinckerhoff, David W Mullins

PLoS One· February 2016

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The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells.
Molly H Jenkins, Walburga Croteau, David W Mullins, Constance E Brinckerhoff

Matrix Biol· October 2015

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BRAF inhibition alleviates immune suppression in murine autochthonous melanoma.
Shannon M Steinberg, Peisheng Zhang, Brian T Malik, Andrea Boni, Tamer B Shabaneh, Constance E Brinckerhoff

Cancer Immunol Res· November 2014

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Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032.
Molly H Jenkins, Shannon M Steinberg, Matthew P Alexander, Jan L Fisher, Marc S Ernstoff, Constance E Brinckerhoff

Pigment Cell Melanoma Res· May 2014

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Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma.
Walburga Croteau, Molly H Jenkins, Siying Ye, David W Mullins, Constance E Brinckerhoff

J Cell Physiol· April 2013

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Distal interleukin-1β (IL-1β) response element of human matrix metalloproteinase-13 (MMP-13) binds activator protein 1 (AP-1) transcription factors and regulates gene expression.
Adam C Schmucker, Jason B Wright, Michael D Cole, Constance E Brinckerhoff

J Biol Chem· January 2012

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Analysis of matrix metalloproteinase-1 gene polymorphisms and expression in benign and malignant breast tumors.
Jing Zhou, Constance Brinckerhoff, Susan Lubert, Kui Yang, Jasmine Saini

Cancer Invest· November 2011

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The 'RASor's' edge: Ras proteins and matrix destruction in arthritis.
Adam C Schmucker, Constance E Brinckerhoff

Arthritis Res Ther· May 2010

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Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer.
Sarah M Eck, Jessica S Blackburn, Adam C Schmucker, Peter S Burrage, Constance E Brinckerhoff

J Autoimmun· January 2010

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Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP.
Charles I Coon, Steven Fiering, Justin Gaudet, Colby A Wyatt, Constance E Brinckerhoff

Matrix Biol· September 2009

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Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression.
Peter S Burrage, Adam C Schmucker, Yanqing Ren, Michael B Sporn, Constance E Brinckerhoff

Arthritis Res Ther· August 2009

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PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma.
Brenda L Petrella, Constance E Brinckerhoff

Cancer Biol Ther· July 2009

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CXCR4 and matrix metalloproteinase-1 are elevated in breast carcinoma-associated fibroblasts and in normal mammary fibroblasts exposed to factors secreted by breast cancer cells.
Sarah M Eck, Anik L Côté, William D Winkelman, Constance E Brinckerhoff

Mol Cancer Res· July 2009

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Wild-type versus mutant MMP-8 in melanoma: 'when you come to a fork in the road, take it'.
Jessica S Blackburn, Constance E Brinckerhoff

Pigment Cell Melanoma Res· June 2009

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Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS.
Jinju Li, Andrew J Ghio, Seung-Hyun Cho, Constance E Brinckerhoff, Sidney A Simon

Environ Health Perspect· March 2009

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Identification of a cigarette smoke-responsive region in the distal MMP-1 promoter.
Becky A Mercer, Alison M Wallace, Constance E Brinckerhoff, Jeanine M D'Armiento

Am J Respir Cell Mol Biol· January 2009

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Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis.
Jessica S Blackburn, Constance E Brinckerhoff

Am J Pathol· December 2008

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Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you?
Matthew P Vincenti, Constance E Brinckerhoff

J Cell Physiol· November 2007

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RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis.
Jessica S Blackburn, C Harker Rhodes, Charles I Coon, Constance E Brinckerhoff

Cancer Res· November 2007

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Regulation of matrix metalloproteinase gene expression by a retinoid X receptor-specific ligand.
Peter S Burrage, Jonathan T Huntington, Michael B Sporn, Constance E Brinckerhoff

Arthritis Rheum· March 2007

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