Publications by authors named "Craig A Strathdee"

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Retargeted oncolytic viruses engineered to remodel the tumor microenvironment for glioblastoma immunotherapy.
Federico Giovannoni, Craig A Strathdee, Camilo Faust Akl, Brian M Andersen, Zhaorong Li

Nat Cancer· December 2025

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Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity.
Camilo Faust Akl, Brian M Andersen, Zhaorong Li, Federico Giovannoni, Martin Diebold, Craig A Strathdee

Nature· July 2025

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Telomerase inhibition is an effective therapeutic strategy in TERT promoter-mutant glioblastoma models with low tumor volume.
Elisa Aquilanti, Lauren Kageler, Jacqueline Watson, Duncan M Baird, Rhiannon E Jones, Craig A Strathdee

Neuro Oncol· July 2023

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Correction to "Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069".
Douglas L Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Craig A Strathdee

J Med Chem· January 2023

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Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists.
Douglas L Orsi, Steven J Ferrara, Stephan Siegel, Anders Friberg, Léa Bouché, Craig A Strathdee

Bioorg Med Chem· January 2023

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Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists and .
Douglas L Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Craig A Strathdee

J Med Chem· November 2022

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A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer.
Stephen Tang, Vidyalakshmi Sethunath, Nebiyou Y Metaferia, Marina F Nogueira, Daniel S Gallant, Craig A Strathdee

Cell Rep· February 2022

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Correction to "Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma".
David E Uehling, Babu Joseph, Kim Chan Chung, Andrew X Zhang, Spencer Ler, Craig A Strathdee

J Med Chem· January 2022

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Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma.
David E Uehling, Babu Joseph, Kim Chan Chung, Andrew X Zhang, Spencer Ler, Craig A Strathdee

J Med Chem· August 2021

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Genetic and transcriptional evolution alters cancer cell line drug response.
Uri Ben-David, Benjamin Siranosian, Gavin Ha, Helen Tang, Yaara Oren, Craig A Strathdee

Nature· August 2018

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Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.
Srinivas R Viswanathan, Marina F Nogueira, Colin G Buss, John M Krill-Burger, Mathias J Wawer, Craig A Strathdee

Nat Genet· July 2018

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Genomic Activation of Reveals a Candidate Therapeutic Axis in Bladder Cancer.
Jonathan T Goldstein, Ashton C Berger, Juliann Shih, Fujiko F Duke, Laura Furst, Craig A Strathdee

Cancer Res· December 2017

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Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Zihao Hua, Howard Bregman, John L Buchanan, Nagasree Chakka, Angel Guzman-Perez, Craig A Strathdee

J Med Chem· December 2013

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Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
Howard Bregman, Nagasree Chakka, Angel Guzman-Perez, Hakan Gunaydin, Yan Gu, Craig A Strathdee

J Med Chem· June 2013

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Robust, reversible gene knockdown using a single lentiviral short hairpin RNA vector.
Cheryl Y Brown, Timothy Sadlon, Tessa Gargett, Elizabeth Melville, Rui Zhang, Craig A Strathdee

Hum Gene Ther· August 2010

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Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells.
Mara S Lippa, Laura D Strockbine, Tiep T Le, Daniel G Branstetter, Craig A Strathdee

Apoptosis· August 2007

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CCL4 protects from type 1 diabetes by altering islet beta-cell-targeted inflammatory responses.
Craig Meagher, Guillermo Arreaza, Andrew Peters, Craig A Strathdee, Philippe A Gilbert

Diabetes· March 2007

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A conditionally replicating adenovirus for nasopharyngeal carcinoma gene therapy.
Marie C Chia, Wei Shi, Jian-Hua Li, Otto Sanchez, Craig A Strathdee

Mol Ther· June 2004

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Regulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formation.
Jacqueline Arp, Mark G Kirchhof, Miren L Baroja, Steven H Nazarian, Thu A Chau, Craig A Strathdee

Mol Cell Biol· November 2003

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A novel costimulatory signaling in human T lymphocytes by a splice variant of CD28.
Haruo Hanawa, Yong Ma, Sebastian A Mikolajczak, Matthew L Charles, Tetsuya Yoshida, Craig A Strathdee

Blood· March 2002

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Tumor-targeted gene therapy for nasopharyngeal carcinoma.
Jian-Hua Li, Marie Chia, Wei Shi, D Ngo, Craig A Strathdee

Cancer Res· January 2002

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