Publications by authors named "Gavin Ha"

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Multiomic assessments of LNCaP and derived cell strains reveal determinants of prostate cancer pathobiology.
Arnab Bose, Armand Bankhead, Ilsa Coleman, Thomas Persse, Wanting Han, Brian Hanratty, Sajida Hassan, Michael Haffner, Colin Pritchard, Gavin Ha

J Clin Invest· November 2025

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Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer.
Juan M Jiménez-Vacas, Daniel Westaby, Ines Figueiredo, Alexis De Haven Brandon, Ana Padilha, Shana Y Trostel, Cindy H Chau, Xiaohu Zhang, Nathan A Lack, Gavin Ha, Johann S de Bono, Adam Sharp

Nat Commun· October 2025

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CHIMERA-DDR: A Machine Learning Framework for Classifying Heterogeneous Mismatch-Repair and Homologous-Recombination Deficiency Patterns in Prostate Cancer.
Komal Sharma, Divin A Wilson, Yu Wang, Shabi Haider, Vineel Bhatlapenumarthi, Shantanu K Jadhav, Bhabishya Neupane, Michael T Schweitzer, Sridhar Rao, Colin C Pritchard, Anai Kthari, Gavin Ha

bioRxiv· October 2025

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Patterns of intra- and intertumor phenotypic heterogeneity in lethal prostate cancer.
Martine P Roudier, Roman Gulati, Erolcan Sayar, Radhika A Patel, Micah Tratt, Helen M Richards, Brian Hanratty, Jimmy L Zhao, Mohamed Adil, Yibai Zhao, Meagan Chambers, Stephanie Harmon, Jessica E Hawley, Michael T Schweizer, Gavin Ha, Charles L Sawyers, Michael C Haffner

J Clin Invest· August 2025

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Patterns of HER2 Expression in Metastatic Prostate and Urothelial Cancers: Implications for HER2-Targeted Therapies.
Hyun Jung Lee, Roman Gulati, Erolcan Sayar, Radhika A Patel, Pushpa Itagi, Helen M Richards, Mohamed Adil, Samantha L Schuster, Jonathan L Wright, Meagan Chambers, Jessica E Hawley, Michael T Schweizer, Gavin Ha, Michael C Haffner, Ruben Raychaudhuri

Cancer Res Commun· August 2025

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Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies.
Sander Frank, Thomas Persse, Ilsa Coleman, Armand Bankhead, Dapei Li, Michael Yang, Brian Hanratty, Michael C Haffner, Colin C Pritchard, Gavin Ha

bioRxiv· May 2025

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Preeclampsia risk prediction from prenatal cell-free DNA screening.
Mohamed Adil, Teodora R Kolarova, Anna-Lisa Doebley, Leah A Chen, Cara L Tobey, Michael Yang, Jonathan B Reichel, Colin C Pritchard, Gavin Ha

Nat Med· April 2025

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RCC1 depletion drives protein transport defects and rupture in micronuclei.
Molly G Zych, Maya Contreras, Manasvita Vashisth, Anna E Mammel, Gavin Ha, Emily M Hatch

bioRxiv· September 2024

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The genomic landscape of lung cancer in never-smokers from the Women's Health Initiative.
Sitapriya Moorthi, Amy Paguirigan, Pushpa Itagi, Minjeong Ko, Mary Pettinger, Anwesha Nag, Gavin Ha

JCI Insight· July 2024

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Assay Validation of Cell-Free DNA Shallow Whole-Genome Sequencing to Determine Tumor Fraction in Advanced Cancers.
Micah Rickles-Young, Gabriel Tinoco, Junko Tsuji, Sam Pollock, Marcy Haynam, Katharine A Collier, Gavin Ha

J Mol Diagn· May 2024

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Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates.
Azra Ajkunic, Erolcan Sayar, Martine P Roudier, Radhika A Patel, Ilsa M Coleman, Brian Hanratty, Mohamed Adil, Jimmy Zhao, Jessica E Hawley, Gavin Ha, Stephanie A Harmon, Charles L Sawyers, Michael T Schweizer, Michael C Haffner

NPJ Precis Oncol· May 2024

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Molecular phenotyping of small cell lung cancer using targeted cfDNA profiling of transcriptional regulatory regions.
Joseph B Hiatt, Anna-Lisa Doebley, Henry U Arnold, Mohamed Adil, Holly Sandborg, Charles M Rudin, Gavin Ha

Sci Adv· April 2024

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FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA.
Yaping Liu, Sarah C Reed, Christopher Lo, Atish D Choudhury, Heather A Parsons, Gavin Ha, Haizi Zheng, Hailu Fu

Nat Commun· March 2024

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FinaleMe: Predicting DNA methylation by the fragmentation patterns of plasma cell-free DNA.
Yaping Liu, Sarah C Reed, Christopher Lo, Atish D Choudhury, Heather A Parsons, Gavin Ha, Haizi Zheng, Hailu Fu

bioRxiv· January 2024

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ASSESSMENT OF CELL SURFACE TARGETS IN METASTATIC PROSTATE CANCER: EXPRESSION LANDSCAPE AND MOLECULAR CORRELATES.
Azra Ajkunic, Erolcan Sayar, Martine P Roudier, Radhika A Patel, Ilsa M Coleman, Brian Hanratty, Mohamed Adil, Jimmy Zhao, Jessica E Hawley, Gavin Ha, Stephanie A Harmon, Charles L Sawyers, Michael T Schweizer, Michael C Haffner

Res Sq· December 2023

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Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3' untranslated region mutations.
Samantha L Schuster, Sonali Arora, Cynthia L Wladyka, Pushpa Itagi, Lukas Corey, Bethany L Stackhouse, Gavin Ha

Cell Rep· August 2023

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Cancer aneuploidies are shaped primarily by effects on tumour fitness.
Juliann Shih, Shahab Sarmashghi, Nadja Zhakula-Kostadinova, Shu Zhang, Yohanna Georgis, Stephanie H Hoyt, Michael S Cuoco, Gavin Ha

Nature· July 2023

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Are Patients with HHV-8 Associated Castleman Disease Successfully Treated with Rituximab at Risk of Subsequently Developing HHV-8 Negative (Idiopathic) Castleman Disease?
Gavin Ha, Kelsey Kwong, Bryce Tanaka, Yoshito Nishimura, Christina Chong

Eur J Case Rep Intern Med· June 2023

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Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes.
Navonil De Sarkar, Robert D Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Michael P Meers, Colin C Pritchard, Michael T Schweizer, Michael C Haffner, Gavin Ha

Cancer Discov· March 2023

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Bipolar androgen therapy plus olaparib in men with metastatic castration-resistant prostate cancer.
Michael T Schweizer, Roman Gulati, Todd Yezefski, Heather H Cheng, Elahe Mostaghel, Michael C Haffner, Gavin Ha, Michael Lai, Jeannette Hammond

Prostate Cancer Prostatic Dis· March 2023

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Genomic Characterization of Prostatic Basal Cell Carcinoma.
Jin-Yih Low, Minjeong Ko, Brian Hanratty, Radhika A Patel, Akshay Bhamidipati, Shan Li, Gavin Ha, Jonathan I Epstein, Michael C Haffner

Am J Pathol· January 2023

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Author Correction: A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA.
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A Eden Cruikshank, Katheryn Santos, Katharine A Collier, Katharine Chen, Zachary T Weber, Mohamed Adil, Jonathan B Reichel, Gavin Ha

Nat Commun· January 2023

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Somatic mutation but not aneuploidy differentiates lung cancer in never-smokers and smokers.
Sitapriya Moorthi, Amy Paguirigan, Minjeong Ko, Mary Pettinger, Anna C H Hoge, Anwesha Nag, Gavin Ha

bioRxiv· January 2023

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A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA.
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A Eden Cruikshank, Katheryn Santos, Katharine A Collier, Katharine Chen, Zachary T Weber, Mohamed Adil, Jonathan B Reichel, Gavin Ha

Nat Commun· December 2022

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Comprehensive assessment of anaplastic lymphoma kinase in localized and metastatic prostate cancer reveals targetable alterations.
Radhika A Patel, Ilsa Coleman, Martine P Roudier, Eric Q Konnick, Brian Hanratty, Gavin Ha, Colin C Pritchard, Michael C Haffner

Cancer Res Commun· May 2022

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