Publications by authors named "Craig Wegner"

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A public-private collaboration model for clinical innovation.
Craig D Wegner, Bobbie Ann Mount, Christine M Colvis

Clin Transl Sci· July 2022

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Inhibition of 11β-Hydroxysteroid dehydrogenase-1 with AZD4017 in patients with nonalcoholic steatohepatitis or nonalcoholic fatty liver disease: A randomized, double-blind, placebo-controlled, phase II study.
Yogesh Yadav, Kelly Dunagan, Rachita Khot, Sudhakar K Venkatesh, John Port, Craig Wegner

Diabetes Obes Metab· May 2022

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Effects of an Oral CRTh2 Antagonist (AZD1981) on Eosinophil Activity and Symptoms in Chronic Spontaneous Urticaria.
Eric Tyrell Oliver, Kris Chichester, Kelly Devine, Patricia Meghan Sterba, Craig Wegner

Int Arch Allergy Immunol· May 2019

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Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Craig D Wegner, Andrew Goodwin, Jon C Cook, Krishna Allamneni, Jane Sohn

Int J Toxicol· April 2018

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Pioneering government-sponsored drug repositioning collaborations: progress and learning.
Donald E Frail, Madeleine Brady, K Jane Escott, Alison Holt, Hitesh J Sanganee, Craig D Wegner

Nat Rev Drug Discov· December 2015

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Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses.
Jonathan B Mitchem, Donal J Brennan, Brett L Knolhoff, Brian A Belt, Yu Zhu, Craig Wegner

Cancer Res· February 2013

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Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival.
Paul Morgan, Piet H Van Der Graaf, John Arrowsmith, Doug E Feltner, Kira S Drummond, Craig D Wegner

Drug Discov Today· May 2012

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Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS).
Chris P Carron, John I Trujillo, Kirk L Olson, Wei Huang, Bruce C Hamper, Craig D Wegner

ACS Med Chem Lett· May 2010

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A method for determining whether hypotension caused by novel compounds in preclinical development results from histamine release.
Jason D Blom, Po-Chang Yang, Nancy S Nicholson, Brenda L Case, John J Parlow, Craig D Wegner

J Pharmacol Toxicol Methods· December 2004

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Nonpeptide luteinizing hormone-releasing hormone antagonists derived from erythromycin A: design, synthesis, and biological activity of cladinose replacement analogues.
John T Randolph, Philip Waid, Charles Nichols, Daryl Sauer, Fortuna Haviv, Craig D Wegner

J Med Chem· February 2004

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Preischemic and postischemic administration of AEOL10113 reduces infarct size in a rat model of myocardial ischemia and reperfusion.
Nathan L Lubbers, James S Polakowski, James D Crapo, Craig D Wegner, Bryan F Cox

J Cardiovasc Pharmacol· May 2003

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Hypertension induced by blockade of ET(B) receptors in conscious nonhuman primates: role of ET(A) receptors.
Glenn A Reinhart, Lee C Preusser, Sandra E Burke, Jerry L Wessale, Craig D Wegner

Am J Physiol Heart Circ Physiol· October 2002

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Evaluation of tissue perfusion in a rat model of hind-limb muscle ischemia using dynamic contrast-enhanced magnetic resonance imaging.
Yanping Luo, Kurt M Mohning, Vincent P Hradil, Jerry L Wessale, Jason A Segreti, Craig D Wegner

J Magn Reson Imaging· September 2002

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Transforming growth factor beta mimetics: discovery of 7-[4-(4-cyanophenyl)phenoxy]-heptanohydroxamic acid, a biaryl hydroxamate inhibitor of histone deacetylase.
Keith B Glaser, Junling Li, Mary E Aakre, Douglas W Morgan, George Sheppard, Craig W Wegner

Mol Cancer Ther· August 2002

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Bimoclomol elevates heat shock protein 70 and cytoprotects rat neonatal cardiomyocytes.
James S Polakowski, Craig D Wegner, Bryan F Cox

Eur J Pharmacol· January 2002

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Oral bimoclomol elevates heat shock protein 70 and reduces myocardial infarct size in rats.
Nathan L Lubbers, James S Polakowski, Craig D Wegner, Sandra E Burke, Gilbert J Diaz

Eur J Pharmacol· January 2002

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