Publications by authors named "Cyril Sanders"

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Identification of hPIF1 helicase inhibitors by virtual screening of a Fsp3-enriched library.
Mark J A Wever, Francesca R Scommegna, Jean-François Poisson, Vincent Rodeschini, Didier Roche, Cyril M Sanders

Bioorg Med Chem Lett· December 2025

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Structure-based discovery of first inhibitors targeting the helicase activity of human PIF1.
Mark J A Wever, Francesca R Scommegna, Sara Egea-Rodriguez, Saba Dehghani-Tafti, Jose Brandao-Neto, Cyril M Sanders

Nucleic Acids Res· November 2024

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Unwinding of a DNA replication fork by a hexameric viral helicase.
Abid Javed, Balazs Major, Jonathan A Stead, Cyril M Sanders, Elena V Orlova

Nat Commun· September 2021

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Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase.
Saba Dehghani-Tafti, Vladimir Levdikov, Alfred A Antson, Ben Bax, Cyril M Sanders

Nucleic Acids Res· April 2019

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DNA substrate recognition and processing by the full-length human UPF1 helicase.
Saba Dehghani-Tafti, Cyril M Sanders

Nucleic Acids Res· July 2017

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Bacteriophage T5 gene D10 encodes a branch-migration protein.
Io Nam Wong, Jon R Sayers, Cyril M Sanders

Sci Rep· December 2016

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Structural basis for DNA strand separation by a hexameric replicative helicase.
Yuriy Chaban, Jonathan A Stead, Ksenia Ryzhenkova, Fiona Whelan, Ekaterina P Lamber, Cyril M Sanders

Nucleic Acids Res· September 2015

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Characterization of an unusual bipolar helicase encoded by bacteriophage T5.
Io Nam Wong, Jon R Sayers, Cyril M Sanders

Nucleic Acids Res· April 2013

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A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding.
Fiona Whelan, Jonathan A Stead, Alexander V Shkumatov, Dmitri I Svergun, Cyril M Sanders

Nucleic Acids Res· March 2012

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Suppression of apoptosis by PIF1 helicase in human tumor cells.
Mary E Gagou, Anil Ganesh, Ruth Thompson, Geraldine Phear, Cyril Sanders

Cancer Res· July 2011

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Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity.
Cyril M Sanders

Biochem J· August 2010

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Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks.
Tresa George, Qin Wen, Richard Griffiths, Anil Ganesh, Mark Meuth, Cyril M Sanders

Nucleic Acids Res· October 2009

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A DNA-binding activity in BPV initiator protein E1 required for melting duplex ori DNA but not processive helicase activity initiated on partially single-stranded DNA.
Cyril M Sanders

Nucleic Acids Res· April 2008

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Papillomavirus E1 helicase assembly maintains an asymmetric state in the absence of DNA and nucleotide cofactors.
Cyril M Sanders, Oleg V Kovalevskiy, Dmytro Sizov, Andrey A Lebedev, Michail N Isupov

Nucleic Acids Res· December 2007

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Transcription activator structure reveals redox control of a replication initiation reaction.
Cyril M Sanders, Dmytro Sizov, Philippa R Seavers, Miguel Ortiz-Lombardía, Alfred A Antson

Nucleic Acids Res· June 2007

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High-specific-activity probes and a high-resolution in-gel photo cross-linking assay for protein-DNA complexes.
Sandrine Castella, Cyril M Sanders

Anal Biochem· December 2006

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Role of ATP hydrolysis in the DNA translocase activity of the bovine papillomavirus (BPV-1) E1 helicase.
Sandrine Castella, David Burgin, Cyril M Sanders

Nucleic Acids Res· August 2006

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Common determinants in DNA melting and helicase-catalysed DNA unwinding by papillomavirus replication protein E1.
Sandrine Castella, Gregg Bingham, Cyril M Sanders

Nucleic Acids Res· June 2006

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