Publications by authors named "Mark Meuth"

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Inhibitors of cell cycle checkpoints and DNA replication cause different responses in normal versus malignant urothelial cells.
Mark Meuth

Mol Cell Oncol· June 2016

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Apoptosis and failure of checkpoint kinase 1 activation in human induced pluripotent stem cells under replication stress.
Joelle A Desmarais, Christian Unger, Ivan Damjanov, Mark Meuth, Peter Andrews

Stem Cell Res Ther· January 2016

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Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells.
Pedro Zuazua-Villar, Anil Ganesh, Geraldine Phear, Mary E Gagou, Mark Meuth

Nucleic Acids Res· November 2015

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Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress.
Mary E Gagou, Anil Ganesh, Geraldine Phear, Darren Robinson, Eva Petermann, Mark Meuth

Oncotarget· November 2014

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Deficient DNA damage response and cell cycle checkpoints lead to accumulation of point mutations in human embryonic stem cells.
Nevila Hyka-Nouspikel, Joëlle Desmarais, Paul J Gokhale, Mark Jones, Mark Meuth

Stem Cells· September 2012

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Human embryonic stem cells fail to activate CHK1 and commit to apoptosis in response to DNA replication stress.
Joëlle A Desmarais, Michele J Hoffmann, Gregg Bingham, Mary E Gagou, Mark Meuth

Stem Cells· July 2012

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Treatment with the Chk1 inhibitor Gö6976 enhances cisplatin cytotoxicity in SCLC cells.
Ruth Thompson, Mark Meuth, Penella Woll, Yong Zhu, Sarah Danson

Int J Oncol· January 2012

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Suppression of apoptosis by PIF1 helicase in human tumor cells.
Mary E Gagou, Anil Ganesh, Ruth Thompson, Geraldine Phear, Cyril Sanders, Mark Meuth

Cancer Res· July 2011

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Chk1 suppressed cell death.
Mark Meuth

Cell Div· September 2010

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Enhanced H2AX phosphorylation, DNA replication fork arrest, and cell death in the absence of Chk1.
Mary E Gagou, Pedro Zuazua-Villar, Mark Meuth

Mol Biol Cell· March 2010

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Distinct microRNA alterations characterize high- and low-grade bladder cancer.
James W F Catto, Saiful Miah, Helen C Owen, Helen Bryant, Katie Myers, Mark Meuth

Cancer Res· November 2009

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Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks.
Tresa George, Qin Wen, Richard Griffiths, Anil Ganesh, Mark Meuth

Nucleic Acids Res· October 2009

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The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links.
Ali Z Al-Minawi, Yin-Fai Lee, Daniel Håkansson, Fredrik Johansson, Cecilia Lundin, Mark Meuth

Nucleic Acids Res· October 2009

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FGFR3 mutations indicate better survival in invasive upper urinary tract and bladder tumours.
Johanna M M van Oers, Ellen C Zwarthoff, Ishtiaq Rehman, Abdel-Rahmene Azzouzi, Olivier Cussenot, Mark Meuth

Eur Urol· March 2009

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ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.
Katie Myers, Mary E Gagou, Pedro Zuazua-Villar, Rene Rodriguez, Mark Meuth

PLoS Genet· January 2009

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Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.
Rene Rodriguez, Lasse Tengbjerg Hansen, Geraldine Phear, Jennifer Scorah, Mogens Spang-Thomsen, Mark Meuth

Clin Cancer Res· September 2008

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A comparison of the performance of microsatellite and methylation urine analysis for predicting the recurrence of urothelial cell carcinoma, and definition of a set of markers by Bayesian network analysis.
Morgan Rouprêt, Vincent Hupertan, David R Yates, Eva Comperat, James W F Catto, Mark Meuth

BJU Int· June 2008

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A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner.
Qin Wen, Jennifer Scorah, Geraldine Phear, Gary Rodgers, Sheila Rodgers, Mark Meuth

Mol Biol Cell· April 2008

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Promoter hypermethylation in circulating blood cells identifies prostate cancer progression.
Morgan Rouprêt, Vincent Hupertan, James W F Catto, David R Yates, Ishtiaq Rehman, Mark Meuth

Int J Cancer· February 2008

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Clinically localised prostate cancer is microsatellite stable.
Abdel-Rahmene Azzouzi, James W F Catto, Ishtiaq Rehman, Stephane Larre, Morgan Roupret, Mark Meuth

BJU Int· May 2007

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Promoter hypermethylation identifies progression risk in bladder cancer.
David R Yates, Ishtiaq Rehman, Maysam F Abbod, Mark Meuth, Simon S Cross

Clin Cancer Res· April 2007

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Molecular detection of localized prostate cancer using quantitative methylation-specific PCR on urinary cells obtained following prostate massage.
Morgan Rouprêt, Vincent Hupertan, David R Yates, James W F Catto, Ishtiaq Rehman, Mark Meuth

Clin Cancer Res· March 2007

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Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumor clearance.
James W F Catto, Arndt Hartmann, Robert Stoehr, Emma Bolderson, Ishtiaq Rehman, Mark Meuth

J Urol· June 2006

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Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress.
Rene Rodriguez, Mark Meuth

Mol Biol Cell· January 2006

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Mark Meuth

Nature· April 2005

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