Publications by authors named "Cyrille Tomassi"

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Progress in the development of small molecule therapeutics targeting Th17 cell function for the treatment of immune-inflammatory diseases.
Stephen Shuttleworth, Paul Townsend, Franck Silva, Alexander Cecil, Thomas Hill, Cyrille Tomassi

Prog Med Chem· October 2011

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Progress in the design and development of phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of chronic diseases.
Stephen Shuttleworth, Franck Silva, Cyrille Tomassi, Alexander Cecil, Thomas Hill

Prog Med Chem· July 2011

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Disubstituted Bis-THF Moieties as New P2 Ligands in Nonpeptidal HIV-1 Protease Inhibitors.
Konrad Hohlfeld, Cyrille Tomassi, Jörg Kurt Wegner, Bart Kesteleyn, Bruno Linclau

ACS Med Chem Lett· June 2011

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The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000.
Leo Leung, Cyrille Tomassi, Katrien Van Beneden, Tine Decruy, Matthias Trappeniers

ChemMedChem· March 2009

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Synthesis and in vivo evaluation of 4-deoxy-4,4-difluoro-KRN7000.
Leo Leung, Cyrille Tomassi, Katrien Van Beneden, Tine Decruy, Dirk Elewaut

Org Lett· October 2008

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Synthesis and anti-HIV1 biological activity of novel 5''-ATSAO compounds.
Cyrille Tomassi, Albert Nguyen Van Nhien, José Marco-Contelles, Jan Balzarini, Christophe Pannecouque

Bioorg Med Chem· April 2008

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Synthesis, anti-HIV-1 activity, and modeling studies of N-3 Boc TSAO compound.
Cyrille Tomassi, Van Nhien Albert Nguyen, José Marco-Contelles, Jan Balzarini, Christophe Pannecouque

Bioorg Med Chem Lett· April 2008

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Enantioselective synthesis and selective monofunctionalization of (4R,6R)-4,6- dihydroxy-2,8-dioxabicyclo[3.3.0]octane.
Bruno Linclau, Martin J Jeffery, Solen Josse, Cyrille Tomassi

Org Lett· December 2006

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Computational analysis of aza analogues of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranose]-3'-spiro-5"-(4"-amino-1",2"-oxathiole-2",2"-dioxide) (TSAO) as HIV-1 reverse transcriptase inhibitors: relevance of conformational properties on the inhibitory activity.
Elena Soriano, José Marco-Contelles, Cyrille Tomassi, Albert Nguyen Van Nhien, Denis Postel

J Chem Inf Model· September 2006

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First synthesis and evaluation of the inhibitory effects of aza analogues of TSAO on HIV-1 replication.
Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini

J Med Chem· June 2005

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Synthesis of 4-amino-5-H-2,3-dihydroisothiazole-1,1-dioxide ring systems on sugar templates via carbanion-mediated sulfonamide intramolecular cyclization reactions (CSIC protocols) of glyco-alpha-sulfonamidonitriles.
Laura Domínguez, Albert Nguyen van Nhien, Cyrille Tomassi, Christophe Len, Denis Postel

J Org Chem· February 2004

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Synthesis of AZA analogues of TSAO.
Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Denis Postel

Nucleosides Nucleotides Nucleic Acids· December 2003

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