Publications by authors named "Franck Silva"

Claim this Profile
U
Unexpected Clinical Drug-Drug Interaction of Fexinidazole on Midazolam Pharmacokinetics: Insights into Underlying Mechanisms from Clinical Phase I Study Results and Supporting In Vivo/Vitro Evidence.
Matthieu Gassiot, Priscilla Brun, Valerie Wauthier, Franck Da Silva, Olivier Nicolas

Clin Drug Investig· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical and phase I studies of KA2237, a selective and potent inhibitor of PI3K β/δ in relapsed refractory B cell lymphoma.
Loretta J Nastoupil, Sattva S Neelapu, Richard Eric Davis, Felipe Samaniego, Nathan H Fowler, Franck A Silva

Leuk Lymphoma· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors.
Apostolia M Tsimberidou, Philip A Beer, Carrie A Cartwright, Cara Haymaker, Henry H Vo, Franck A Silva

Clin Cancer Res· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exhaustive Repertoire of Druggable Cavities at Protein-Protein Interfaces of Known Three-Dimensional Structure.
Franck Da Silva, Guillaume Bret, Leandro Teixeira, Claudio F Gonzalez, Didier Rognan

J Med Chem· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Unsupervised Classification of G-Protein Coupled Receptors and Their Conformational States Using IChem Intramolecular Interaction Patterns.
Florian Koensgen, Franck Da Silva, Didier Rognan, Esther Kellenberger

J Chem Inf Model· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Based Detection of Orthosteric and Allosteric Pockets at Protein-Protein Interfaces.
Franck Da Silva, Didier Rognan

Methods Mol Biol· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
All in One: Cavity Detection, Druggability Estimate, Cavity-Based Pharmacophore Perception, and Virtual Screening.
Viet-Khoa Tran-Nguyen, Franck Da Silva, Guillaume Bret, Didier Rognan

J Chem Inf Model· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin Binding.
Franck Da-Silva, Xavier Boulenc, Hélène Vermet, Pauline Compigne, Sabine Gerbal-Chaloin

J Pharm Sci· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IChem: A Versatile Toolkit for Detecting, Comparing, and Predicting Protein-Ligand Interactions.
Franck Da Silva, Jeremy Desaphy, Didier Rognan

ChemMedChem· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Ranking docking poses by graph matching of protein-ligand interactions: lessons learned from the D3R Grand Challenge 2.
Priscila da Silva Figueiredo Celestino Gomes, Franck Da Silva, Guillaume Bret, Didier Rognan

J Comput Aided Mol Des· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Docking pose selection by interaction pattern graph similarity: application to the D3R grand challenge 2015.
Inna Slynko, Franck Da Silva, Guillaume Bret, Didier Rognan

J Comput Aided Mol Des· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.
Philippe Briolotti, Laurent Chaloin, Patrick Balaguer, Franck Da Silva, Veronika Tománková

Toxicol Sci· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IChemPIC: A Random Forest Classifier of Biological and Crystallographic Protein-Protein Interfaces.
Franck Da Silva, Jérémy Desaphy, Guillaume Bret, Didier Rognan

J Chem Inf Model· September 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Game on, science - how video game technology may help biologists tackle visualization challenges.
Zhihan Lv, Alex Tek, Franck Da Silva, Charly Empereur-mot, Matthieu Chavent

PLoS One· September 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Progress in the development of small molecule therapeutics targeting Th17 cell function for the treatment of immune-inflammatory diseases.
Stephen Shuttleworth, Paul Townsend, Franck Silva, Alexander Cecil, Thomas Hill

Prog Med Chem· October 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Progress in the design and development of phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of chronic diseases.
Stephen Shuttleworth, Franck Silva, Cyrille Tomassi, Alexander Cecil, Thomas Hill

Prog Med Chem· July 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Gold(I)-catalyzed alkoxyhalogenation of beta-hydroxy-alpha,alpha-difluoroynones.
Marie Schuler, Franck Silva, Carla Bobbio, Arnaud Tessier, Véronique Gouverneur

Angew Chem Int Ed Engl· November 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enantioselective organocatalytic aldol reaction of ynones and its synthetic applications.
Franck Silva, Marcin Sawicki, Véronique Gouverneur

Org Lett· November 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pd(II)-catalyzed cascade Wacker-Heck reaction: chemoselective coupling of two electron-deficient reactants.
Franck Silva, Maud Reiter, Rebecca Mills-Webb, Marcin Sawicki, Daniel Klär

J Org Chem· October 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis