Publications by authors named "Dane D Jensen"

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Nanoparticle-mediated antagonism of sustained endosomal signaling of the calcitonin receptor-like receptor provides enhanced and persistent relief of oral cancer pain.
Chloe J Peach, Nguyen Huu Tu, Parker K Lewis, Rachel E Pollard, Badr Sokrat, Dane D Jensen

Biomaterials· April 2026

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Endosomal MrGPRX1 signaling sensitizes TRPV1 to enhance itch.
Paz Duran, Jeffri S Retamal, Marcella de Amorim Ferreira, Kai Trevett, Dane D Jensen

bioRxiv· November 2025

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A Bacteroides fragilis protease activates host PAR to induce intestinal pain and inflammation.
Markus Lakemeyer, Rocco Latorre, Kristyna Blazkova, Hannah M Wood, Dane D Jensen

Cell Host Microbe· October 2025

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Nanomedicines targeting protease-activated receptor 2 in endosomes provide sustained analgesia.
Shavonne L Teng, Rocco Latorre, Divya Bhansali, Parker K Lewis, Rachel E Pollard, Dane D Jensen

Proc Natl Acad Sci U S A· October 2025

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Targeting prostaglandin E receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation.
Romina Nassini, Lorenzo Landini, Matilde Marini, Martina Chieca, Daniel Souza Monteiro de Araújo, Dane D Jensen

Nat Commun· September 2025

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Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Dane D Jensen

Br J Pharmacol· August 2025

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PAR on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ3451.
Divya Bhansali, Nguyen H Tu, Kenji Inoue, Shavonne Teng, Tianyu Li, Dane D Jensen

Biomaterials· March 2025

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Characterization and targeting of the endosomal signaling of the gastrin releasing peptide receptor in pruritus.
Jeffri Retamal Santibañez, Diana Bok, Shavonne Teng, Divya Bhansali, Marcella de Amorim Ferreira, Dane D Jensen

bioRxiv· March 2025

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Comparative Analysis of Nucleic Acid-Binding Polymers as Potential Anti-Inflammatory Nanocarriers.
Divya Bhansali, Tolulope Akinade, Tianyu Li, Yiling Zhong, Feng Liu, Dane D Jensen

Pharmaceutics· December 2023

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Repurposing EGFR Inhibitors for Oral Cancer Pain and Opioid Tolerance.
Maria Daniela Santi, Morgan Zhang, Naijiang Liu, Chi T Viet, Tongxin Xie, Dane D Jensen

Pharmaceuticals (Basel)· November 2023

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Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Alan Hegron, Chloe J Peach, Raquel Tonello, Philipp Seemann, Shavonne Teng, Dane D Jensen

Proc Natl Acad Sci U S A· May 2023

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Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2.
Ying Xie, Lindsey Fontenot, Andrea Chupina Estrada, Becca Nelson, Jiani Wang, Dane D Jensen

Cell Mol Gastroenterol Hepatol· September 2022

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Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain.
Rocco Latorre, Paulina D Ramírez-Garcia, Alan Hegron, James L Grace, Jeffri S Retamal, Dane D Jensen

Biomaterials· June 2022

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Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects.
Nestor Nivardo Jiménez-Vargas, Yang Yu, Dane D Jensen, Diana Daeun Bok, Matthew Wisdom

Gut· April 2022

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Mice expressing fluorescent PAR reveal that endocytosis mediates colonic inflammation and pain.
Rocco Latorre, Alan Hegron, Chloe J Peach, Shavonne Teng, Raquel Tonello, Dane D Jensen

Proc Natl Acad Sci U S A· February 2022

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Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice.
Francesco De Logu, Romina Nassini, Alan Hegron, Lorenzo Landini, Dane D Jensen

Nat Commun· February 2022

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Cathepsin S Evokes PAR-Dependent Pain in Oral Squamous Cell Carcinoma Patients and Preclinical Mouse Models.
Nguyen Huu Tu, Kenji Inoue, Elyssa Chen, Bethany M Anderson, Caroline M Sawicki, Dane D Jensen

Cancers (Basel)· September 2021

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Legumain Induces Oral Cancer Pain by Biased Agonism of Protease-Activated Receptor-2.
Nguyen Huu Tu, Dane D Jensen, Bethany M Anderson, Elyssa Chen, Nestor N Jimenez-Vargas

J Neurosci· January 2021

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Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain.
Nestor N Jimenez-Vargas, Jing Gong, Matthew J Wisdom, Dane D Jensen, Rocco Latorre

Proc Natl Acad Sci U S A· June 2020

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A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.
Paulina D Ramírez-García, Jeffri S Retamal, Priyank Shenoy, Wendy Imlach, Matthew Sykes, Dane D Jensen

Nat Nanotechnol· December 2019

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Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression.
Narek Israelyan, Andrew Del Colle, Zhishan Li, Yeji Park, Albert Xing, Dane D Jensen

Gastroenterology· August 2019

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Protein kinase D and Gβγ mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2.
Peishen Zhao, Luke A Pattison, Dane D Jensen, Nestor N Jimenez-Vargas, Rocco Latorre

J Biol Chem· July 2019

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Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors.
Alex R B Thomsen, Dane D Jensen, Gareth A Hicks, Nigel W Bunnett

Trends Pharmacol Sci· October 2018

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Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
Nestor N Jimenez-Vargas, Luke A Pattison, Peishen Zhao, TinaMarie Lieu, Rocco Latorre, Dane D Jensen

Proc Natl Acad Sci U S A· July 2018

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Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system.
Hua Peng, Dane D Jensen, Wencheng Li, Michelle N Sullivan, Sophie A Buller

Am J Physiol Heart Circ Physiol· March 2018

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