Publications by authors named "Paz Duran"

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Endosomal MrGPRX1 signaling sensitizes TRPV1 to enhance itch.
Paz Duran, Jeffri S Retamal, Marcella de Amorim Ferreira, Kai Trevett, Dane D Jensen

bioRxiv· November 2025

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A Bacteroides fragilis protease activates host PAR to induce intestinal pain and inflammation.
Markus Lakemeyer, Rocco Latorre, Kristyna Blazkova, Hannah M Wood, Dane D Jensen, Paz Duran

Cell Host Microbe· October 2025

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Nanomedicines targeting protease-activated receptor 2 in endosomes provide sustained analgesia.
Shavonne L Teng, Rocco Latorre, Divya Bhansali, Parker K Lewis, Rachel E Pollard, Paz Duran

Proc Natl Acad Sci U S A· October 2025

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Mouse models of non-dystrophic and dystrophic myotonia exhibit nociplastic pain-like behaviors.
Tyler S Nelson, Aida Calderon-Rivera, Heather N Allen, Emanuel Loeza-Alcocer, Jorge B Pineda-Farias, Paz Duran

bioRxiv· June 2025

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The Leucine-Rich Repeat Kinase 2 Variant LRRK2 Up-Regulates L-Type (CaV1.3) Calcium Channel via the Caβ Subunit: Possible Role in the Pathogenesis of Parkinson's Disease.
Alejandro Sandoval, Alejandra Corzo-López, Paz Duran, Diana Tovar-Soto, Bryan Vargas-Caballero

Int J Mol Sci· March 2025

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Small molecule targeting Na V 1.7 via inhibition of CRMP2-Ubc9 interaction reduces pain-related outcomes in a rodent osteoarthritic model.
Sara Hestehave, Heather N Allen, Kimberly Gomez, Paz Duran, Aida Calderon-Rivera

Pain· January 2025

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Uncoupling the CRMP2-Ca2.2 Interaction Reduces Pain-Like Behavior in a Preclinical Joint-Pain Model.
Heather N Allen, Sara Hestehave, Paz Duran, Tyler S Nelson, Rajesh Khanna

J Pain· December 2024

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C2230, a preferential use- and state-dependent CaV2.2 channel blocker, mitigates pain behaviors across multiple pain models.
Cheng Tang, Kimberly Gomez, Yan Chen, Heather N Allen, Sara Hestehave, Paz Duran

J Clin Invest· December 2024

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Green light exposure in children with autism spectrum disorder: a pilot study.
Caroline M Sawicki, Paz Duran, Sara Hestehave, Rajesh Khanna, Spencer D Wade

J Clin Pediatr Dent· July 2024

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C-H Functionalization-Enabled 11-Step Semisynthesis of (-)-Veragranine A and Characterization of Synthetic Analogs in Osteoarthritis-related Pain Treatment.
Donghui Ma, Paz Duran, Reem Al-Ahmad, Sara Hestehave, Margarita Joa

J Am Chem Soc· June 2024

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Regulating neuronal excitability: The role of -palmitoylation in Na1.7 activity and voltage sensitivity.
Cheng Tang, Paz Duran, Aida Calderon-Rivera, Santiago Loya-Lopez, Kimberly Gomez

PNAS Nexus· June 2024

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Uncoupling the CRMP2-Ca2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model.
Heather N Allen, Sara Hestehave, Paz Duran, Tyler S Nelson, Rajesh Khanna

bioRxiv· June 2024

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The role of voltage-gated calcium channels in the pathogenesis of Parkinson's disease.
Alejandro Sandoval, Paz Duran, Alejandra Corzo-López, Miriam Fernández-Gallardo, David Muñoz-Herrera

Int J Neurosci· May 2024

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Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain.
Kimberly Gomez, Heather N Allen, Paz Duran, Santiago Loya-Lopez, Aida Calderon-Rivera

Pain· April 2024

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Intranasal CRMP2-Ubc9 inhibitor regulates Na V 1.7 to alleviate trigeminal neuropathic pain.
Santiago I Loya-Lopez, Heather N Allen, Paz Duran, Aida Calderon-Rivera, Kimberly Gomez

Pain· March 2024

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Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors.
Kimberly Gomez, Paz Duran, Raquel Tonello, Heather N Allen, Lisa Boinon

Pain· December 2023

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A peptidomimetic modulator of the Ca2.2 N-type calcium channel for chronic pain.
Kimberly Gomez, Ulises Santiago, Tyler S Nelson, Heather N Allen, Aida Calderon-Rivera, Paz Duran

Proc Natl Acad Sci U S A· November 2023

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Identification and targeting of a unique Na1.7 domain driving chronic pain.
Kimberly Gomez, Harrison J Stratton, Paz Duran, Santiago Loya, Cheng Tang

Proc Natl Acad Sci U S A· August 2023

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Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain.
Harrison J Stratton, Lisa Boinon, Kimberly Gomez, Laurent Martin, Paz Duran

Pain· July 2023

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Intranasal CRMP2-Ubc9 Inhibitor Regulates Na 1.7 to Alleviate Trigeminal Neuropathic Pain.
Santiago I Loya-Lopez, Heather N Allen, Paz Duran, Aida Calderon-Rivera, Kimberly Gomez

bioRxiv· July 2023

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The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.
Paz Duran, Santiago Loya-López, Dongzhi Ran, Cheng Tang, Aida Calderon-Rivera

Br J Pharmacol· May 2023

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Some Like It Hot: Dynamic Control of Cav2.2 Channels By Chili Peppers.
Paz Duran, Rajesh Khanna

Function (Oxf)· January 2023

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Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain.
Aida Calderon-Rivera, Kimberly Gomez, Santiago Loya-López, E M Kithsiri Wijeratne, Harrison Stratton, Paz Duran

Neurobiol Pain· January 2023

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The ubiquitin E3 ligase Parkin regulates neuronal Ca1.3 channel functional expression.
Lizbeth Grimaldo, Alejandro Sandoval, Paz Duran, Liliana Gómez Flores-Ramos, Ricardo Felix

J Neurophysiol· December 2022

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Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons.
Santiago I Loya-López, Paz Duran, Dongzhi Ran, Aida Calderon-Rivera, Kimberly Gomez

Neurobiol Pain· November 2022

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