Publications by authors named "Daniel Bottomley"

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Tumour-Infiltrating Lymphocytes, Tumour Cell Density, and Response to Neoadjuvant Short-Course Radiotherapy in Rectal Cancer: A Translational Sub-Study from the MRC CR07 Clinical Trial.
Jonathan P Callaghan, Ross Jarrett, Alice C Westwood, Jon Laye, Philip Quirke, Daniel Bottomley

Cancers (Basel)· September 2025

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Perioperative changes in the microbiome during rectal cancer surgery: exploratory analysis of the National Institute for Health and Care Research (NIHR) IntAct trial.
Jack A Helliwell, Caroline H Chilton, Caroline Young, Emma V Clark, Lyndsay Wilkinson, Daniel Bottomley

Br J Surg· September 2025

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Standard versus reduced-dose chemoradiotherapy in anal cancer (PLATO-ACT4): short-term results of a phase 2 randomised controlled trial.
Alexandra Gilbert, Richard Adams, Joanne Webster, Duncan C Gilbert, Natalie L Abbott, Daniel Bottomley

Lancet Oncol· June 2025

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The ATOM-Seq sequence capture panel can accurately predict microsatellite instability status in formalin-fixed tumour samples, alongside routine gene mutation testing.
Kanishta Srihar, Arief Gusnanto, Susan D Richman, Nicholas P West, Leanne Galvin, Daniel Bottomley

Sci Rep· September 2024

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Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer.
Christopher J M Williams, Faye Elliott, Nancy Sapanara, Faranak Aghaei, Liping Zhang, Daniel Bottomley

Clin Cancer Res· October 2023

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Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy.
Caroline Young, Henry M Wood, Alba Fuentes Balaguer, Daniel Bottomley, Niall Gallop

Clin Cancer Res· April 2021

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Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer.
Anna Wilkins, Elisa Fontana, Gift Nyamundanda, Chanthirika Ragulan, Yatish Patil, Daniel Bottomley

J Immunother Cancer· March 2021

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Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA.
Thomas L Dunwell, Simon C Dailey, Anine L Ottestad, Jihang Yu, Philipp W Becker, Daniel Bottomley

Sci Rep· February 2021

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Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations.
Simon Gollins, Nick West, David Sebag-Montefiore, Arthur Sun Myint, Mark Saunders, Daniel Bottomley

Br J Cancer· October 2017

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