Publications by authors named "Daniel Buzard"

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C-H activation reactions as useful tools for medicinal chemists.
Eduardo J E Caro-Diaz, Mariangela Urbano, Daniel J Buzard, Robert M Jones

Bioorg Med Chem Lett· November 2016

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Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series.
Sangdon Han, Sanju Narayanan, Sun Hee Kim, Imelda Calderon, Xiuwen Zhu, Daniel J Buzard

Bioorg Med Chem Lett· August 2015

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Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor.
Daniel J Buzard, Thomas O Schrader, Xiuwen Zhu, Juerg Lehmann, Ben Johnson

Bioorg Med Chem Lett· February 2015

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Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor.
Daniel J Buzard, Sun Hee Kim, Luis Lopez, Andrew Kawasaki, Xiuwen Zhu

ACS Med Chem Lett· December 2014

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(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists.
Daniel J Buzard, Luis Lopez, Jeanne Moody, Andrew Kawasaki, Thomas O Schrader

ACS Med Chem Lett· December 2014

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Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists.
Daniel J Buzard, Sun Hee Kim, Juerg Lehmann, Sangdon Han, Imelda Calderon

Bioorg Med Chem Lett· September 2014

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Kinetics of 5-HT2B receptor signaling: profound agonist-dependent effects on signaling onset and duration.
David J Unett, Joel Gatlin, Todd L Anthony, Daniel J Buzard, Steve Chang

J Pharmacol Exp Ther· December 2013

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Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists.
Sangdon Han, Jayant Thatte, Daniel J Buzard, Robert M Jones

J Med Chem· November 2013

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Complementary asymmetric routes to (R)-2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate.
Thomas O Schrader, Benjamin R Johnson, Luis Lopez, Michelle Kasem, Tawfik Gharbaoui, Daniel Buzard

Org Lett· December 2012

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Fused tricyclic indoles as S1P₁ agonists with robust efficacy in animal models of autoimmune disease.
Daniel J Buzard, Sangdon Han, Luis Lopez, Andrew Kawasaki, Jeanne Moody

Bioorg Med Chem Lett· July 2012

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GPR119 agonists 2009-2011.
Daniel J Buzard, Juerg Lehmann, Sangdon Han, Robert M Jones

Pharm Pat Anal· July 2012

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Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P₁ agonists.
Daniel Buzard, Sangdon Han, Lars Thoresen, Jeanne Moody, Luis Lopez

Bioorg Med Chem Lett· October 2011

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Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands.
Brad M Savall, James P Edwards, Jennifer D Venable, Daniel J Buzard, Robin Thurmond

Bioorg Med Chem Lett· June 2010

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GPR119 agonists for the treatment of type 2 diabetes.
Robert M Jones, James N Leonard, Daniel J Buzard, Juerg Lehmann

Expert Opin Ther Pat· October 2009

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Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands.
Alice Lee-Dutra, Kristen L Arienti, Daniel J Buzard, Michael D Hack, Haripada Khatuya

Bioorg Med Chem Lett· December 2006

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